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A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice.
Ramasamy V, Arora U, Shukla R, Poddar A, Shanmugam RK, White LJ, Mattocks MM, Raut R, Perween A, Tyagi P, de Silva AM, Bhaumik SK, Kaja MK, Villinger F, Ahmed R, Johnston RE, Swaminathan S, Khanna N. Ramasamy V, et al. Among authors: shukla r. PLoS Negl Trop Dis. 2018 Jan 8;12(1):e0006191. doi: 10.1371/journal.pntd.0006191. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29309412 Free PMC article.
Next generation designer virus-like particle vaccines for dengue.
Shukla R, Ramasamy V, Rajpoot RK, Arora U, Poddar A, Ahuja R, Beesetti H, Swaminathan S, Khanna N. Shukla R, et al. Expert Rev Vaccines. 2019 Feb;18(2):105-117. doi: 10.1080/14760584.2019.1562909. Epub 2019 Jan 17. Expert Rev Vaccines. 2019. PMID: 30587054 Review.
2,072 results