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Page 1
Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain.
Chuapoco MR, Flytzanis NC, Goeden N, Christopher Octeau J, Roxas KM, Chan KY, Scherrer J, Winchester J, Blackburn RJ, Campos LJ, Man KNM, Sun J, Chen X, Lefevre A, Singh VP, Arokiaraj CM, Shay TF, Vendemiatti J, Jang MJ, Mich JK, Bishaw Y, Gore BB, Omstead V, Taskin N, Weed N, Levi BP, Ting JT, Miller CT, Deverman BE, Pickel J, Tian L, Fox AS, Gradinaru V. Chuapoco MR, et al. Among authors: taskin n. Nat Nanotechnol. 2023 Oct;18(10):1241-1251. doi: 10.1038/s41565-023-01419-x. Epub 2023 Jul 10. Nat Nanotechnol. 2023. PMID: 37430038 Free PMC article.
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore BB, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V. Chen X, et al. Among authors: taskin n. Nat Commun. 2023 Jun 8;14(1):3345. doi: 10.1038/s41467-023-38582-7. Nat Commun. 2023. PMID: 37291094 Free PMC article.
Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex.
Lee BR, Dalley R, Miller JA, Chartrand T, Close J, Mann R, Mukora A, Ng L, Alfiler L, Baker K, Bertagnolli D, Brouner K, Casper T, Csajbok E, Donadio N, Driessens SLW, Egdorf T, Enstrom R, Galakhova AA, Gary A, Gelfand E, Goldy J, Hadley K, Heistek TS, Hill D, Hou WH, Johansen N, Jorstad N, Kim L, Kocsis AK, Kruse L, Kunst M, León G, Long B, Mallory M, Maxwell M, McGraw M, McMillen D, Melief EJ, Molnar G, Mortrud MT, Newman D, Nyhus J, Opitz-Araya X, Ozsvár A, Pham T, Pom A, Potekhina L, Rajanbabu R, Ruiz A, Sunkin SM, Szöts I, Taskin N, Thyagarajan B, Tieu M, Trinh J, Vargas S, Vumbaco D, Waleboer F, Walling-Bell S, Weed N, Williams G, Wilson J, Yao S, Zhou T, Barzó P, Bakken T, Cobbs C, Dee N, Ellenbogen RG, Esposito L, Ferreira M, Gouwens NW, Grannan B, Gwinn RP, Hauptman JS, Hodge R, Jarsky T, Keene CD, Ko AL, Korshoej AR, Levi BP, Meier K, Ojemann JG, Patel A, Ruzevick J, Silbergeld DL, Smith K, Sørensen JC, Waters J, Zeng H, Berg J, Capogna M, Goriounova NA, Kalmbach B, de Kock CPJ, Mansvelder HD, Sorensen SA, Tamas G, Lein ES, Ting JT. Lee BR, et al. Among authors: taskin n. Science. 2023 Oct 13;382(6667):eadf6484. doi: 10.1126/science.adf6484. Epub 2023 Oct 13. Science. 2023. PMID: 37824669 Free PMC article.
Classification of electrophysiological and morphological neuron types in the mouse visual cortex.
Gouwens NW, Sorensen SA, Berg J, Lee C, Jarsky T, Ting J, Sunkin SM, Feng D, Anastassiou CA, Barkan E, Bickley K, Blesie N, Braun T, Brouner K, Budzillo A, Caldejon S, Casper T, Castelli D, Chong P, Crichton K, Cuhaciyan C, Daigle TL, Dalley R, Dee N, Desta T, Ding SL, Dingman S, Doperalski A, Dotson N, Egdorf T, Fisher M, de Frates RA, Garren E, Garwood M, Gary A, Gaudreault N, Godfrey K, Gorham M, Gu H, Habel C, Hadley K, Harrington J, Harris JA, Henry A, Hill D, Josephsen S, Kebede S, Kim L, Kroll M, Lee B, Lemon T, Link KE, Liu X, Long B, Mann R, McGraw M, Mihalas S, Mukora A, Murphy GJ, Ng L, Ngo K, Nguyen TN, Nicovich PR, Oldre A, Park D, Parry S, Perkins J, Potekhina L, Reid D, Robertson M, Sandman D, Schroedter M, Slaughterbeck C, Soler-Llavina G, Sulc J, Szafer A, Tasic B, Taskin N, Teeter C, Thatra N, Tung H, Wakeman W, Williams G, Young R, Zhou Z, Farrell C, Peng H, Hawrylycz MJ, Lein E, Ng L, Arkhipov A, Bernard A, Phillips JW, Zeng H, Koch C. Gouwens NW, et al. Among authors: taskin n. Nat Neurosci. 2019 Jul;22(7):1182-1195. doi: 10.1038/s41593-019-0417-0. Epub 2019 Jun 17. Nat Neurosci. 2019. PMID: 31209381 Free PMC article.
HCN channels reveal conserved and divergent physiology in supragranular pyramidal neurons in primate species.
Radaelli C, Schmitz M, Liu XP, Sawchuk S, Opitz-Araya X, Hudson M, Taskin N, Bertagnolli D, Goldy J, Ko AL, Grannan BL, Hauptman JS, Patel AP, Cobbs C, Smith KA, Spain WJ, Lein ES, Bakken T, Dembrow NC, Ting JT, Kalmbach BE. Radaelli C, et al. Among authors: taskin n. bioRxiv [Preprint]. 2025 Aug 23:2025.08.22.671856. doi: 10.1101/2025.08.22.671856. bioRxiv. 2025. PMID: 40894563 Free PMC article. Preprint.
Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque.
Kussick E, Johansen N, Taskin N, Chowdhury A, Quinlan MA, Fraser A, Clark AG, Wynalda B, Martinez R, Groce EL, Reding M, Liang E, Shulga L, Huang C, Casper T, Clark M, Ho W, Gao Y, van Velthoven CTJ, Sobieski C, Ferrer R, Berg MR, Curtis BC, English C, Day JC, Fortuna MG, Donadio N, Newman D, Yao S, Chakka AB, Goldy J, Torkelson A, Guzman JB, Chakrabarty R, Nguy B, Guilford N, Pham TH, Wright V, Ronellenfitch K, Naidoo R, Kenney J, Williford A, Ramakrishnan C, Drinnenberg A, Gudsnuk K, Thyagarajan B, Smith KA, Dee N, Deisseroth K, Zeng H, Yao Z, Tasic B, Levi BP, Hodge R, Bakken TE, Lein ES, Ting JT, Daigle TL. Kussick E, et al. Among authors: taskin n. Cell Rep. 2025 Jun 24;44(6):115730. doi: 10.1016/j.celrep.2025.115730. Epub 2025 May 21. Cell Rep. 2025. PMID: 40403722 Free article.
Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits.
Hunker AC, Wirthlin ME, Gill G, Johansen NJ, Hooper M, Omstead V, Vargas S, Lerma MN, Taskin N, Weed N, Laird WD, Bishaw YM, Bendrick JL, Gore BB, Ben-Simon Y, Opitz-Araya X, Martinez RA, Way SW, Thyagarajan B, Otto S, Sanchez REA, Alexander JR, Amaya A, Amster A, Arbuckle J, Ayala A, Baker PM, Barcelli T, Barta S, Bertagnolli D, Bielstein C, Bishwakarma P, Bowlus J, Boyer G, Brouner K, Casian B, Casper T, Chakka AB, Chakrabarty R, Chong P, Clark M, Colbert K, Daniel S, Dawe T, Departee M, DiValentin P, Donadio NP, Dotson NI, Dwivedi D, Egdorf T, Fliss T, Gary A, Goldy J, Grasso C, Groce EL, Gudsnuk K, Han W, Haradon Z, Hastings S, Helback O, Ho WV, Huang C, Johnson T, Jones DL, Juneau Z, Kenney J, Leibly M, Li S, Liang E, Loeffler H, Lusk NA, Madigan Z, Malloy J, Malone J, McCue R, Melchor J, Mich JK, Moosman S, Morin E, Naidoo R, Newman D, Ngo K, Nguyen K, Oster AL, Ouellette B, Oyama AA, Pena N, Pham T, Phillips E, Pom C, Potekhina L, Ransford S, Ray PL, Reding M, Rette DF, Reynoldson C, Rimorin C, Sigler AR, Rocha DB, Ronellenfitch K, Ruiz A, Sawyer L, Sevigny JP, Shapovalova NV, Shepard N, Shulga L, Soliman S, Staats B, Taormina MJ, Tieu M, Wang Y, Wilkes J, Wood T, Zh… See abstract for full author list ➔ Hunker AC, et al. Among authors: taskin n. Neuron. 2025 May 21;113(10):1507-1524.e17. doi: 10.1016/j.neuron.2025.04.035. Neuron. 2025. PMID: 40403704 Free PMC article.
Technical and biological sources of noise confound multiplexed enhancer AAV screening.
Hunker AC, Mich JK, Taskin N, Torkelson A, Pham T, Bertagnolli D, Chakka AB, Chakrabarty R, Donadio NP, Ferrer R, Gasperini M, Goldy J, Guzman JB, Jin K, Khem S, Kutsal R, Lalanne JB, Martinez RA, Newman D, Pena N, Shapovalova NV, Weed N, Zhou T, Yao S, Shendure J, Smith KA, Lein ES, Tasic B, Levi BP, Ting JT. Hunker AC, et al. Among authors: taskin n. bioRxiv [Preprint]. 2025 Jan 16:2025.01.14.633018. doi: 10.1101/2025.01.14.633018. bioRxiv. 2025. PMID: 39868122 Free PMC article. Preprint.
Distinctive physiology of molecularly identified medium spiny neurons in the macaque putamen.
Ting JT, Johansen NJ, Kalmbach BE, Taskin N, Lee B, Clark JK, Kendrick R, Ng L, Radaelli C, Weed N, Enstrom R, Ransford S, Redford I, Walling-Bell S, Dalley R, Tieu M, Goldy J, Jorstad N, Smith K, Bakken T, Lein ES, Owen SF. Ting JT, et al. Among authors: taskin n. Cell Rep. 2024 Nov 26;43(11):114963. doi: 10.1016/j.celrep.2024.114963. Epub 2024 Nov 7. Cell Rep. 2024. PMID: 39514389 Free PMC article.
33 results