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MOADE: a multimodal autoencoder for dissociating bulk multi-omics data.
Sun J, Malik AA, Lin T, Bratton A, Pan Y, Smith K, Onar-Thomas A, Robinson GW, Zhang W, Northcott PA, Li Q. Sun J, et al. Among authors: lin t. Genome Biol. 2025 Sep 30;26(1):325. doi: 10.1186/s13059-025-03805-1. Genome Biol. 2025. PMID: 41029754 Free PMC article.
An integrated analysis of three medulloblastoma clinical trials refines risk-stratification approaches for reducing toxicity and improving survival.
Smith AKS, Dhanda SK, Billups CA, Sioson E, Lu C, Peraza AZ, Gangwani K, Li Y, Li Q, Lin T, Michalski JM, Packer RJ, Olson JM, Leary SES, Fouladi M, Gajjar A, Zhou X, Onar-Thomas A, Northcott PA, Robinson GW. Smith AKS, et al. Among authors: lin t. Neuro Oncol. 2025 Oct 24:noaf250. doi: 10.1093/neuonc/noaf250. Online ahead of print. Neuro Oncol. 2025. PMID: 41159377
Comparison of DNA methylation based classification models for precision diagnostics of central nervous system tumors.
Tran QT, Breuer A, Lin T, Tatevossian R, Allen SJ, Clay M, Furtado LV, Chen M, Hedges D, Michael T, Robinson G, Northcott P, Gajjar A, Azzato E, Shurtleff S, Ellison DW, Pounds S, Orr BA. Tran QT, et al. Among authors: lin t. NPJ Precis Oncol. 2024 Oct 2;8(1):218. doi: 10.1038/s41698-024-00718-3. NPJ Precis Oncol. 2024. PMID: 39358389 Free PMC article.
Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis.
Lehman NL, Usubalieva A, Lin T, Allen SJ, Tran QT, Mobley BC, McLendon RE, Schniederjan MJ, Georgescu MM, Couce M, Dulai MS, Raisanen JM, Al Abbadi M, Palmer CA, Hattab EM, Orr BA. Lehman NL, et al. Among authors: lin t. Acta Neuropathol Commun. 2019 Mar 15;7(1):42. doi: 10.1186/s40478-019-0689-3. Acta Neuropathol Commun. 2019. PMID: 30876455 Free PMC article.
DNA Methylation Profiling Reveals Prognostically Significant Groups in Pediatric Adrenocortical Tumors: A Report From the International Pediatric Adrenocortical Tumor Registry.
Clay MR, Pinto EM, Cline C, Tran QT, Lin T, Dyer MA, Shi L, Wu H, Pounds SB, Zambetti GP, Orr BA, Ribeiro RC. Clay MR, et al. Among authors: lin t. JCO Precis Oncol. 2019 Nov 18;3:PO.19.00163. doi: 10.1200/PO.19.00163. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32923859 Free PMC article.
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