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Investigating the promising SARS-CoV-2 main protease inhibitory activity of secoiridoids isolated from Jasminum humile; in silico and in Vitro assessments with structure-activity relationship.
Al-Karmalawy AA, Alnajjar R, Elmaaty AA, Binjubair FA, Al-Rashood ST, Mansour BS, Elkamhawy A, Eldehna WM, Mansour KA. Al-Karmalawy AA, et al. Among authors: al rashood st. J Biomol Struct Dyn. 2024 Aug;42(13):6941-6953. doi: 10.1080/07391102.2023.2240419. Epub 2023 Jul 28. J Biomol Struct Dyn. 2024. PMID: 37505066
Physiological and biochemical responses of Kinnow mandarin grafted on diploid and tetraploid Volkamer lemon rootstocks under different water-deficit regimes.
Khalid MF, Hussain S, Anjum MA, Morillon R, Ahmad S, Ejaz S, Hussain M, Jaafar HZE, Alrashood ST, Ormenisan AN. Khalid MF, et al. PLoS One. 2021 Apr 8;16(4):e0247558. doi: 10.1371/journal.pone.0247558. eCollection 2021. PLoS One. 2021. Retraction in: PLoS One. 2022 Nov 16;17(11):e0277636. doi: 10.1371/journal.pone.0277636. PMID: 33831006 Free PMC article. Retracted.
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents.
Eldehna WM, Abo-Ashour MF, Nocentini A, El-Haggar RS, Bua S, Bonardi A, Al-Rashood ST, Hassan GS, Gratteri P, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Eur J Med Chem. 2019 Jan 15;162:147-160. doi: 10.1016/j.ejmech.2018.10.068. Epub 2018 Nov 2. Eur J Med Chem. 2019. PMID: 30445264
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX.
Eldehna WM, Abo-Ashour MF, Berrino E, Vullo D, Ghabbour HA, Al-Rashood ST, Hassan GS, Alkahtani HM, Almehizia AA, Alharbi A, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Bioorg Chem. 2019 Mar;83:549-558. doi: 10.1016/j.bioorg.2018.11.014. Epub 2018 Nov 14. Bioorg Chem. 2019. PMID: 30471577
Type IIA - Type IIB protein tyrosine kinase inhibitors hybridization as an efficient approach for potent multikinase inhibitor development: Design, synthesis, anti-proliferative activity, multikinase inhibitory activity and molecular modeling of novel indolinone-based ureides and amides.
Eldehna WM, El Kerdawy AM, Al-Ansary GH, Al-Rashood ST, Ali MM, Mahmoud AE. Eldehna WM, et al. Eur J Med Chem. 2019 Feb 1;163:37-53. doi: 10.1016/j.ejmech.2018.11.061. Epub 2018 Nov 24. Eur J Med Chem. 2019. PMID: 30503942
77 results