Ginder GD - Search Results

1

Analysis of the complex between MBD2 and the histone deacetylase core of NuRD reveals key interactions critical for gene silencing.

Leighton GO, Shang S, Hageman S, Ginder GD, Williams DC Jr. Leighton GO, et al. Among authors: ginder gd. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2307287120. doi: 10.1073/pnas.2307287120. Epub 2023 Aug 8. Proc Natl Acad Sci U S A. 2023. PMID: 37552759 Free PMC article.

2

MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression.

Shang S, Li X, Azzo A, Truong T, Dozmorov M, Lyons C, Manna AK, Williams DC Jr, Ginder GD. Shang S, et al. Among authors: ginder gd. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2302254120. doi: 10.1073/pnas.2302254120. Epub 2023 Jun 12. Proc Natl Acad Sci U S A. 2023. PMID: 37307480 Free PMC article.

3

Src inhibition potentiates MCL-1 antagonist activity in acute myeloid leukemia.

Hu X, Li L, Nkwocha J, Kmieciak M, Shang S, Cowart LA, Yue Y, Horimoto K, Hawkridge A, Rijal A, Mauro AG, Salloum FN, Hazlehurst L, Sdrimas K, Moore Z, Zhou L, Ginder GD, Grant S. Hu X, et al. Among authors: ginder gd. Signal Transduct Target Ther. 2025 Feb 10;10(1):50. doi: 10.1038/s41392-025-02125-x. Signal Transduct Target Ther. 2025. PMID: 39924517 Free PMC article.

4

The role of multivalency in the association of the eight twenty-one protein 2 (ETO2) with the nucleosome remodeling and deacetylase (NuRD) complex.

Dan-Dukor G, Shang S, Leighton GO, Travis CR, Schwochert TD, Agrawal P, Ajasa O, Li T, Waters ML, Ginder GD, Williams DC Jr. Dan-Dukor G, et al. Among authors: ginder gd. Nucleic Acids Res. 2025 May 22;53(10):gkaf439. doi: 10.1093/nar/gkaf439. Nucleic Acids Res. 2025. PMID: 40421803 Free PMC article.

5

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence.

Appiah CO, Singh M, May L, Bakshi I, Vaidyanathan A, Dent P, Ginder G, Grant S, Bear H, Landry J. Appiah CO, et al. Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6. Adv Cancer Res. 2023. PMID: 36990536 Review.

6

Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human adult erythroid cells.

Yu X, Azzo A, Bilinovich SM, Li X, Dozmorov M, Kurita R, Nakamura Y, Williams DC Jr, Ginder GD. Yu X, et al. Among authors: ginder gd. Haematologica. 2019 Dec;104(12):2361-2371. doi: 10.3324/haematol.2018.210963. Epub 2019 Apr 19. Haematologica. 2019. PMID: 31004025 Free PMC article.

7

Corrigendum to "Readers of DNA methylation, the MBD family as potential therapeutic targets" [Pharmacology & Therapeutics 184 (1) (2018) 98-111].

Ginder GD, Williams DC Jr. Ginder GD, et al. Pharmacol Ther. 2018 Oct;190:237-238. doi: 10.1016/j.pharmthera.2018.09.006. Pharmacol Ther. 2018. PMID: 30268235 No abstract available.

8

Readers of DNA methylation, the MBD family as potential therapeutic targets.

Ginder GD, Williams DC Jr. Ginder GD, et al. Pharmacol Ther. 2018 Apr;184:98-111. doi: 10.1016/j.pharmthera.2017.11.002. Epub 2017 Nov 8. Pharmacol Ther. 2018. PMID: 29128342 Free PMC article. Review.

9

In Vitro Erythroid Differentiation and Lentiviral Knockdown in Human CD34+ Cells from Umbilical Cord Blood.

Kovilakath A, Mohamad S, Hermes F, Wang SZ, Ginder GD, Lloyd JA. Kovilakath A, et al. Among authors: ginder gd. Methods Mol Biol. 2018;1698:259-274. doi: 10.1007/978-1-4939-7428-3_16. Methods Mol Biol. 2018. PMID: 29076096

10

Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.

Sperlazza J, Rahmani M, Beckta J, Aust M, Hawkins E, Wang SZ, Zu Zhu S, Podder S, Dumur C, Archer K, Grant S, Ginder GD. Sperlazza J, et al. Among authors: ginder gd. Blood. 2015 Sep 17;126(12):1462-72. doi: 10.1182/blood-2015-03-631606. Epub 2015 Aug 11. Blood. 2015. PMID: 26265695 Free PMC article.

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