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Characterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets.
Bremmer F, Pongratanakul P, Skowron M, Che Y, Richter A, Küffer S, Reuter-Jessen K, Bohnenberger H, Pauls S, Kresbach C, Schüller U, Stühler K, Ströbel P, Albers P, Nettersheim D. Bremmer F, et al. Among authors: che y. Br J Cancer. 2023 Nov;129(10):1580-1589. doi: 10.1038/s41416-023-02425-5. Epub 2023 Sep 19. Br J Cancer. 2023. PMID: 37726478 Free PMC article.
Late relapsing germ cell tumors with elevated tumor markers.
Che Y, Lusch A, Winter C, Große Siemer R, Buddensieck C, Albers P, Hiester A. Che Y, et al. World J Urol. 2022 Feb;40(2):363-371. doi: 10.1007/s00345-021-03833-z. Epub 2021 Sep 13. World J Urol. 2022. PMID: 34518930 Free PMC article.
Misuse of tumor marker levels leads to an insufficient International Germ Cell Consensus Classification (IGCCCG) risk group assignment and impaired treatment.
Majewski M, Paffenholz P, Ruf C, Che Y, Seidel C, Heinzelbecker J, Schmelz HU, Matthies C, Albers P, Bokemeyer C, Heidenreich A, Pichler M, Nestler T; GTCSG (German Testicular Cancer Study Group). Majewski M, et al. Among authors: che y. Cancer Med. 2023 Aug;12(16):16829-16836. doi: 10.1002/cam4.6304. Epub 2023 Jul 1. Cancer Med. 2023. PMID: 37392170 Free PMC article.
Assessing the risk to develop a growing teratoma syndrome based on molecular and epigenetic subtyping as well as novel secreted biomarkers.
Pongratanakul P, Bremmer F, Pauls S, Poschmann G, Kresbach C, Parmaksiz F, Skowron MA, Fuß J, Stephan A, Paffenholz P, Stühler K, Schüller U, Ströbel P, Heidenreich A, Che Y, Albers P, Nettersheim D. Pongratanakul P, et al. Among authors: che y. Cancer Lett. 2024 Mar 31;585:216673. doi: 10.1016/j.canlet.2024.216673. Epub 2024 Jan 29. Cancer Lett. 2024. PMID: 38296184 Free article.
Molecular and epigenetic ex vivo profiling of testis cancer-associated fibroblasts and their interaction with germ cell tumor cells and macrophages.
Stephan A, Suhrmann JH, Skowron MA, Che Y, Poschmann G, Petzsch P, Kresbach C, Wruck W, Pongratanakul P, Adjaye J, Stühler K, Köhrer K, Schüller U, Nettersheim D. Stephan A, et al. Among authors: che y. Matrix Biol. 2024 Sep;132:10-23. doi: 10.1016/j.matbio.2024.06.001. Epub 2024 Jun 6. Matrix Biol. 2024. PMID: 38851302 Free article.
2,099 results