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Page 1
IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma.
Karakousi T, Cristaldi V, Lopes de Oliveira ML, Delclaux I, Besson NR, Geraldo LH, González-Robles TJ, McDonnough DR, Martinez-Krams D, da Silva G, Breazeale AP, Encarnacion-Rosado J, Pozniak J, Qiu S, Illa Bochaca I, Kaiza ME, Kim HM, Bruno TC, Reizis B, Moshiri AS, Kimmelman AC, Ruggles KV, Osman I, Marine JC, Chandel NS, Lund AW. Karakousi T, et al. Among authors: besson nr. Cancer Cell. 2026 Jan 22:S1535-6108(25)00553-7. doi: 10.1016/j.ccell.2025.12.019. Online ahead of print. Cancer Cell. 2026. PMID: 41576931
A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma.
Zhao W, Nguyen TT, Bhagwat A, Kumar A, Giotti B, Kepecs B, Weirather JL, Mahadevan NR, Segerstolpe A, Dolasia K, Abdul-Ghafar J, Besson NR, Jones SM, Soong BY, Li C, Vigneau S, Slyper M, Wakiro I, Su MJ, Helvie K, Frangieh A, Jane-Valbuena J, Ashenberg O, Awad M, Rotem A, Bueno R, Rozenblatt-Rosen O, Pfaff K, Rodig S, Hata AN, Regev A, Johnson BE, Tsankov AM. Zhao W, et al. Among authors: besson nr. Nat Cancer. 2025 Nov;6(11):1857-1879. doi: 10.1038/s43018-025-01053-7. Epub 2025 Oct 7. Nat Cancer. 2025. PMID: 41057692
Dual Immune Checkpoint Inhibition in Patients With Aggressive Thyroid Carcinoma: A Phase 2 Nonrandomized Clinical Trial.
Sehgal K, Pappa T, Shin KY, Schiantarelli J, Liu M, Ricker C, Besson NR, Jones SM, Welsh EL, Pfaff KL, Barletta JA, Park J, Reardon B, Doherty GM, Alexander EK, Rodig SJ, Barbie DA, O'Neill A, Van Allen E, Haddad RI, Lorch JH. Sehgal K, et al. Among authors: besson nr. JAMA Oncol. 2024 Dec 1;10(12):1663-1671. doi: 10.1001/jamaoncol.2024.4019. JAMA Oncol. 2024. PMID: 39446365 Free PMC article. Clinical Trial.
Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors.
Hoffman SE, Dowrey TW, Villacorta Martin C, Bi K, Titchen B, Johri S, DelloStritto L, Patel M, Mackichan C, Inga S, Chen J, Grimaldi G, Napolitano S, Wakiro I, Wu J, Yeung J, Rotem A, Sicinska E, Shannon E, Clancy T, Wang J, Denning S, Brais L, Besson NR, Pfaff KL, Huang Y, Kao KZ, Rodig S, Hornick JL, Vigneau S, Park J, Kulke MH, Chan J, Van Allen EM, Murphy GJ. Hoffman SE, et al. Among authors: besson nr. Sci Adv. 2023 Sep 29;9(39):eadd9668. doi: 10.1126/sciadv.add9668. Epub 2023 Sep 27. Sci Adv. 2023. PMID: 37756410 Free PMC article.
A cellular and spatial atlas of TP53 -associated tissue remodeling in lung adenocarcinoma.
Zhao W, Kepecs B, Mahadevan NR, Segerstolpe A, Weirather JL, Besson NR, Giotti B, Soong BY, Li C, Vigneau S, Slyper M, Wakiro I, Jane-Valbuena J, Ashenberg O, Rotem A, Bueno R, Rozenblatt-Rosen O, Pfaff K, Rodig S, Hata AN, Regev A, Johnson BE, Tsankov AM. Zhao W, et al. Among authors: besson nr. bioRxiv [Preprint]. 2024 Feb 14:2023.06.28.546977. doi: 10.1101/2023.06.28.546977. bioRxiv. 2024. Update in: Nat Cancer. 2025 Nov;6(11):1857-1879. doi: 10.1038/s43018-025-01053-7. PMID: 37425718 Free PMC article. Updated. Preprint.