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AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.
Dashti A, Sukkestad S, Horner AM, Neja M, Siddiqi Z, Waller C, Goldy J, Monroe D, Lin A, Schoof N, Singh V, Mavigner M, Lifson JD, Deleage C, Tuyishime M, Falcinelli SD, King HAD, Ke R, Mason RD, Archin NM, Dunham RM, Safrit JT, Jean S, Perelson AS, Margolis DM, Ferrari G, Roederer M, Silvestri G, Chahroudi A. Dashti A, et al. Among authors: archin nm. Nat Med. 2023 Oct;29(10):2535-2546. doi: 10.1038/s41591-023-02570-7. Epub 2023 Oct 2. Nat Med. 2023. PMID: 37783968 Free PMC article.
Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal.
Gray CN, Ashokkumar M, Janssens DH, Kirchherr J, Allard B, Hsieh E, Hafer TL, Archin NM, Browne EP, Emerman M. Gray CN, et al. Among authors: archin nm. bioRxiv [Preprint]. 2025 Feb 19:2024.08.30.610517. doi: 10.1101/2024.08.30.610517. bioRxiv. 2025. Update in: Elife. 2025 Apr 10;13:RP103064. doi: 10.7554/eLife.103064. PMID: 39257755 Free PMC article. Updated. Preprint.
Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells.
Anderson JA, Archin NM, Ince W, Parker D, Wiegand A, Coffin JM, Kuruc J, Eron J, Swanstrom R, Margolis DM. Anderson JA, et al. Among authors: archin nm. J Virol. 2011 May;85(10):5220-3. doi: 10.1128/JVI.00284-11. Epub 2011 Mar 2. J Virol. 2011. PMID: 21367910 Free PMC article.
114 results