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Page 1
Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides.
Adams R, Joyce C, Kuravskiy M, Harrison K, Ahdash Z, Balmforth M, Chia K, Marceddu C, Coates M, Snowden J, Goursaud E, Ménochet K, van den Elsen J, Payne RJ, Lawson ADG, Scott-Tucker A, Macpherson A. Adams R, et al. Among authors: balmforth m. Front Immunol. 2023 May 12;14:1170357. doi: 10.3389/fimmu.2023.1170357. eCollection 2023. Front Immunol. 2023. PMID: 37251411 Free PMC article.
Discovery and chemical optimisation of a potent, Bi-cyclic antimicrobial inhibitor of Escherichia coli PBP3.
Rowland CE, Newman H, Martin TT, Dods R, Bournakas N, Wagstaff JM, Lewis N, Stanway SJ, Balmforth M, Kessler C, van Rietschoten K, Bellini D, Roper DI, Lloyd AJ, Dowson CG, Skynner MJ, Beswick P, Dawson MJ. Rowland CE, et al. Among authors: balmforth m. Commun Biol. 2025 May 28;8(1):819. doi: 10.1038/s42003-025-08246-x. Commun Biol. 2025. PMID: 40437113 Free PMC article.
Synthesis and screening of a library of Lewisx deoxyfluoro-analogues reveals differential recognition by glycan-binding partners.
Hollingsworth K, Di Maio A, Richards SJ, Vendeville JB, Wheatley DE, Council CE, Keenan T, Ledru H, Chidwick H, Huang K, Parmeggiani F, Marchesi A, Chai W, McBerney R, Kamiński TP, Balmforth MR, Tamasanu A, Finnigan JD, Young C, Warriner SL, Webb ME, Fascione MA, Flitsch S, Galan MC, Feizi T, Gibson MI, Liu Y, Turnbull WB, Linclau B. Hollingsworth K, et al. Among authors: balmforth mr. Nat Commun. 2024 Sep 13;15(1):7925. doi: 10.1038/s41467-024-51081-7. Nat Commun. 2024. PMID: 39271664 Free PMC article.
An Assay for Periplasm Entry Advances the Development of Chimeric Peptide Antibiotics.
Wagstaff JM, Balmforth M, Lewis N, Dods R, Rowland C, van Rietschoten K, Chen L, Harrison H, Skynner MJ, Dawson M, Ivanova-Berndt G, Beswick P. Wagstaff JM, et al. Among authors: balmforth m. ACS Infect Dis. 2020 Sep 11;6(9):2355-2361. doi: 10.1021/acsinfecdis.0c00389. Epub 2020 Aug 15. ACS Infect Dis. 2020. PMID: 32697574