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Page 1
Serotonin reduction in post-acute sequelae of viral infection.
Wong AC, Devason AS, Umana IC, Cox TO, Dohnalová L, Litichevskiy L, Perla J, Lundgren P, Etwebi Z, Izzo LT, Kim J, Tetlak M, Descamps HC, Park SL, Wisser S, McKnight AD, Pardy RD, Kim J, Blank N, Patel S, Thum K, Mason S, Beltra JC, Michieletto MF, Ngiow SF, Miller BM, Liou MJ, Madhu B, Dmitrieva-Posocco O, Huber AS, Hewins P, Petucci C, Chu CP, Baraniecki-Zwil G, Giron LB, Baxter AE, Greenplate AR, Kearns C, Montone K, Litzky LA, Feldman M, Henao-Mejia J, Striepen B, Ramage H, Jurado KA, Wellen KE, O'Doherty U, Abdel-Mohsen M, Landay AL, Keshavarzian A, Henrich TJ, Deeks SG, Peluso MJ, Meyer NJ, Wherry EJ, Abramoff BA, Cherry S, Thaiss CA, Levy M. Wong AC, et al. Among authors: wellen ke. Cell. 2023 Oct 26;186(22):4851-4867.e20. doi: 10.1016/j.cell.2023.09.013. Epub 2023 Oct 16. Cell. 2023. PMID: 37848036 Free PMC article.
Therapeutic targeting of ACLY in T-ALL in vivo.
da Silva-Diz V, Singh A, Aleksandrova M, Kim O, Thai C, Lancho O, Nunes PR, Affronti H, Su X, Wellen KE, Herranz D. da Silva-Diz V, et al. Among authors: wellen ke. bioRxiv [Preprint]. 2024 Jun 20:2023.03.27.534395. doi: 10.1101/2023.03.27.534395. bioRxiv. 2024. PMID: 37034581 Free PMC article. Preprint.
Dysregulated metabolism contributes to oncogenesis.
Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team. Hirschey MD, et al. Among authors: wellen ke. Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Semin Cancer Biol. 2015. PMID: 26454069 Free PMC article. Review.
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.
McDonald OG, Li X, Saunders T, Tryggvadottir R, Mentch SJ, Warmoes MO, Word AE, Carrer A, Salz TH, Natsume S, Stauffer KM, Makohon-Moore A, Zhong Y, Wu H, Wellen KE, Locasale JW, Iacobuzio-Donahue CA, Feinberg AP. McDonald OG, et al. Among authors: wellen ke. Nat Genet. 2017 Mar;49(3):367-376. doi: 10.1038/ng.3753. Epub 2017 Jan 16. Nat Genet. 2017. PMID: 28092686 Free PMC article.
IDH mutation impairs histone demethylation and results in a block to cell differentiation.
Lu C, Ward PS, Kapoor GS, Rohle D, Turcan S, Abdel-Wahab O, Edwards CR, Khanin R, Figueroa ME, Melnick A, Wellen KE, O'Rourke DM, Berger SL, Chan TA, Levine RL, Mellinghoff IK, Thompson CB. Lu C, et al. Among authors: wellen ke. Nature. 2012 Feb 15;483(7390):474-8. doi: 10.1038/nature10860. Nature. 2012. PMID: 22343901 Free PMC article.
Interplay between epigenetics & cancer metabolism.
Gupta V, Gopinath P, Iqbal MA, Mazurek S, Wellen KE, Bamezai RN. Gupta V, et al. Among authors: wellen ke. Curr Pharm Des. 2014;20(11):1706-14. doi: 10.2174/13816128113199990536. Curr Pharm Des. 2014. PMID: 23888952
101 results