Couce A - Search Results

1

Changing fitness effects of mutations through long-term bacterial evolution.

Couce A, Limdi A, Magnan M, Owen SV, Herren CM, Lenski RE, Tenaillon O, Baym M. Couce A, et al. Science. 2024 Jan 26;383(6681):eadd1417. doi: 10.1126/science.add1417. Epub 2024 Jan 26. Science. 2024. PMID: 38271521

2

Effect of recA inactivation on mutagenesis of Escherichia coli exposed to sublethal concentrations of antimicrobials.

Thi TD, López E, Rodríguez-Rojas A, Rodríguez-Beltrán J, Couce A, Guelfo JR, Castañeda-García A, Blázquez J. Thi TD, et al. Among authors: couce a. J Antimicrob Chemother. 2011 Mar;66(3):531-8. doi: 10.1093/jac/dkq496. Epub 2011 Jan 5. J Antimicrob Chemother. 2011. PMID: 21212055

3

Assessing the emergence of resistance: the absence of biological cost in vivo may compromise fosfomycin treatments for P. aeruginosa infections.

Rodríguez-Rojas A, Maciá MD, Couce A, Gómez C, Castañeda-García A, Oliver A, Blázquez J. Rodríguez-Rojas A, et al. Among authors: couce a. PLoS One. 2010 Apr 15;5(4):e10193. doi: 10.1371/journal.pone.0010193. PLoS One. 2010. PMID: 20419114 Free PMC article.

4

Frequency of spontaneous resistance to fosfomycin combined with different antibiotics in Pseudomonas aeruginosa.

Rodríguez-Rojas A, Couce A, Blázquez J. Rodríguez-Rojas A, et al. Among authors: couce a. Antimicrob Agents Chemother. 2010 Nov;54(11):4948-9. doi: 10.1128/AAC.00415-10. Epub 2010 Aug 16. Antimicrob Agents Chemother. 2010. PMID: 20713658 Free PMC article. No abstract available.

5

Estimating mutation rates in low-replication experiments.

Couce A, Blázquez J. Couce A, et al. Mutat Res. 2011 Sep 1;714(1-2):26-32. doi: 10.1016/j.mrfmmm.2011.06.005. Epub 2011 Jun 28. Mutat Res. 2011. PMID: 21736881

6

The rule of declining adaptability in microbial evolution experiments.

Couce A, Tenaillon OA. Couce A, et al. Front Genet. 2015 Mar 11;6:99. doi: 10.3389/fgene.2015.00099. eCollection 2015. Front Genet. 2015. PMID: 25815007 Free PMC article.

7

Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria.

Couce A, Caudwell LV, Feinauer C, Hindré T, Feugeas JP, Weigt M, Lenski RE, Schneider D, Tenaillon O. Couce A, et al. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9026-E9035. doi: 10.1073/pnas.1705887114. Epub 2017 Oct 10. Proc Natl Acad Sci U S A. 2017. PMID: 29073099 Free PMC article.

8

Mutation bias and GC content shape antimutator invasions.

Couce A, Tenaillon O. Couce A, et al. Nat Commun. 2019 Jul 15;10(1):3114. doi: 10.1038/s41467-019-11217-6. Nat Commun. 2019. PMID: 31308380 Free PMC article.

9

Flux, toxicity, and expression costs generate complex genetic interactions in a metabolic pathway.

Kemble H, Eisenhauer C, Couce A, Chapron A, Magnan M, Gautier G, Le Nagard H, Nghe P, Tenaillon O. Kemble H, et al. Among authors: couce a. Sci Adv. 2020 Jun 3;6(23):eabb2236. doi: 10.1126/sciadv.abb2236. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32537514 Free PMC article.

10

The evolution of robustness and fragility during long-term bacterial adaptation.

Chihoub D, Pintard C, Lenski RE, Tenaillon O, Couce A. Chihoub D, et al. Among authors: couce a. Proc Natl Acad Sci U S A. 2025 Apr 22;122(16):e2501901122. doi: 10.1073/pnas.2501901122. Epub 2025 Apr 15. Proc Natl Acad Sci U S A. 2025. PMID: 40232797 Free PMC article.

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