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Page 1
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.
Nguyen BV, Özden C, Dong K, Koc OC, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankara S, Abromson NL, Tomchick DR, Fissore RA, Chen J, Garman SC, Stratton MM. Nguyen BV, et al. Among authors: stratton mm. Nat Commun. 2025 Sep 26;16(1):8461. doi: 10.1038/s41467-025-63249-w. Nat Commun. 2025. PMID: 41006217 Free PMC article.
Role of CAMK2D in neurodevelopment and associated conditions.
Rigter PMF, de Konink C, Dunn MJ, Proietti Onori M, Humberson JB, Thomas M, Barnes C, Prada CE, Weaver KN, Ryan TD, Caluseriu O, Conway J, Calamaro E, Fong CT, Wuyts W, Meuwissen M, Hordijk E, Jonkers CN, Anderson L, Yuseinova B, Polonia S, Beysen D, Stark Z, Savva E, Poulton C, McKenzie F, Bhoj E, Bupp CP, Bézieau S, Mercier S, Blevins A, Wentzensen IM, Xia F, Rosenfeld JA, Hsieh TC, Krawitz PM, Elbracht M, Veenma DCM, Schulman H, Stratton MM, Küry S, van Woerden GM. Rigter PMF, et al. Among authors: stratton mm. Am J Hum Genet. 2025 Sep 4;112(9):2247. doi: 10.1016/j.ajhg.2025.08.001. Epub 2025 Aug 11. Am J Hum Genet. 2025. PMID: 40795868 Free PMC article. No abstract available.
Bacterial ubiquitin ligase engineered for small molecule and protein target identification.
Ye JS, Majumdar A, Park BC, Black MH, Hsieh TS, Osinski A, Servage KA, Kulkarni K, Naidoo J, Alto NM, Stratton MM, Alfandari D, Ready JM, Pawłowski K, Tomchick DR, Tagliabracci VS. Ye JS, et al. Among authors: stratton mm. bioRxiv [Preprint]. 2025 Mar 22:2025.03.20.644192. doi: 10.1101/2025.03.20.644192. bioRxiv. 2025. PMID: 40166235 Free PMC article. Preprint.
Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer.
Yang X, Ma X, Zhao T, Croucher DR, Nguyen EV, Clark KC, Hu C, Latham SL, Bayly-Jones C, Nguyen BV, Budnar S, Shin SY, Nguyen LK, Cotton TR, Chüeh AC, Lim Kam Sian TCC, Stratton MM, Ellisdon AM, Daly RJ. Yang X, et al. Among authors: stratton mm. Nat Commun. 2025 Feb 22;16(1):1871. doi: 10.1038/s41467-025-57046-8. Nat Commun. 2025. PMID: 39984440 Free PMC article.
A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.
Nguyen BV, Özden C, Dong K, Koc OC, Torres-Ocampo AP, Dziedzic N, Flaherty D, Huang J, Sankara S, Abromson NL, Tomchick DR, Fissore RA, Chen J, Garman SC, Stratton MM. Nguyen BV, et al. Among authors: stratton mm. bioRxiv [Preprint]. 2025 May 20:2024.03.24.586494. doi: 10.1101/2024.03.24.586494. bioRxiv. 2025. Update in: Nat Commun. 2025 Sep 26;16(1):8461. doi: 10.1038/s41467-025-63249-w. PMID: 38585726 Free PMC article. Updated. Preprint.
Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer.
Yang X, Ma X, Zhao T, Croucher DR, Nguyen EV, Clark KC, Hu C, Latham SL, Bayly-Jones C, Nguyen VCB, Budnar S, Shin S, Nguyen LK, Cotton TR, Chueh AC, Sian TCLK, Stratton MM, Ellisdon AM, Daly RJ. Yang X, et al. Among authors: stratton mm. bioRxiv [Preprint]. 2024 Nov 22:2024.02.14.580406. doi: 10.1101/2024.02.14.580406. bioRxiv. 2024. Update in: Nat Commun. 2025 Feb 22;16(1):1871. doi: 10.1038/s41467-025-57046-8. PMID: 38405732 Free PMC article. Updated. Preprint.
Role of CAMK2D in neurodevelopment and associated conditions.
Rigter PMF, de Konink C, Dunn MJ, Proietti Onori M, Humberson JB, Thomas M, Barnes C, Prada CE, Weaver KN, Ryan TD, Caluseriu O, Conway J, Calamaro E, Fong CT, Wuyts W, Meuwissen M, Hordijk E, Jonkers CN, Anderson L, Yuseinova B, Polonia S, Beysen D, Stark Z, Savva E, Poulton C, McKenzie F, Bhoj E, Bupp CP, Bézieau S, Mercier S, Blevins A, Wentzensen IM, Xia F, Rosenfeld JA, Hsieh TC, Krawitz PM, Elbracht M, Veenma DCM, Schulman H, Stratton MM, Küry S, van Woerden GM. Rigter PMF, et al. Among authors: stratton mm. Am J Hum Genet. 2024 Feb 1;111(2):364-382. doi: 10.1016/j.ajhg.2023.12.016. Epub 2024 Jan 24. Am J Hum Genet. 2024. PMID: 38272033 Free PMC article.
28 results