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LOXL2-mediated chromatin compaction is required to maintain the oncogenic properties of triple-negative breast cancer cells.
Serra-Bardenys G, Blanco E, Escudero-Iriarte C, Serra-Camprubí Q, Querol J, Pascual-Reguant L, Morancho B, Escorihuela M, Tissera NS, Sabé A, Martín L, Segura-Bayona S, Verde G, Aiese Cigliano R, Millanes-Romero A, Jerónimo C, Cebrià-Costa JP, Nuciforo P, Simonetti S, Viaplana C, Dienstmann R, Oliveira M, Peg V, Stracker TH, Arribas J, Canals F, Villanueva J, Di Croce L, García de Herreros A, Tian TV, Peiró S. Serra-Bardenys G, et al. Among authors: stracker th. FEBS J. 2024 Jun;291(11):2423-2448. doi: 10.1111/febs.17112. Epub 2024 Mar 7. FEBS J. 2024. PMID: 38451841 Free article.
De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency.
Villamor-Payà M, Sanchiz-Calvo M, Smak J, Pais L, Sud M, Shankavaram U, Lovgren AK, Austin-Tse C, Ganesh VS, Gay M, Vilaseca M, Arauz-Garofalo G, Palenzuela L, VanNoy G, O'Donnell-Luria A, Stracker TH. Villamor-Payà M, et al. Among authors: stracker th. iScience. 2024 May 18;27(6):109984. doi: 10.1016/j.isci.2024.109984. eCollection 2024 Jun 21. iScience. 2024. PMID: 38868186 Free PMC article.
Peroxiredoxin 1 safeguards the nucleolar genome from oxidative damage.
Furusawa T, Gujar V, Sharma S, Boateng F, Li H, Achour C, Taniyama D, Pommier Y, Oberdoerffer S, Stracker TH, Weyemi U. Furusawa T, et al. Among authors: stracker th. bioRxiv [Preprint]. 2025 Nov 13:2025.11.12.685177. doi: 10.1101/2025.11.12.685177. bioRxiv. 2025. PMID: 41293000 Free PMC article. Preprint.
Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition.
Li H, Furusawa T, Cavero R, Xiao Y, Chari R, Wu X, Sun D, Hartmann O, Dhall A, Holewinski R, Andresson T, Karim B, Villamor-Payà M, Gallardo D, Day CP, Pal LR, Nair NU, Ruppin E, Aladjem MI, Pommier Y, Diefenbacher ME, Lim JM, Levine RL, Stracker TH, Weyemi U. Li H, et al. Among authors: stracker th. Redox Biol. 2025 Mar;80:103503. doi: 10.1016/j.redox.2025.103503. Epub 2025 Jan 19. Redox Biol. 2025. PMID: 39854937 Free PMC article.
Identification of Novel Modulators of the ALT Pathway Through a Native FISH-Based Optical Screen.
Azeroglu B, Khurana S, Wang SC, Tricola GM, Sharma S, Jubelin C, Cortolezzis Y, Pegoraro G, Miller KM, Stracker TH, Denchi EL. Azeroglu B, et al. Among authors: stracker th. bioRxiv [Preprint]. 2024 Nov 15:2024.11.15.623791. doi: 10.1101/2024.11.15.623791. bioRxiv. 2024. Update in: Cell Rep. 2025 Jan 28;44(1):115114. doi: 10.1016/j.celrep.2024.115114. PMID: 39605432 Free PMC article. Updated. Preprint.
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