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An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders.
Dorion MF, Casas D, Shlaifer I, Yaqubi M, Fleming P, Karpilovsky N, Chen CX, Nicouleau M, Piscopo VEC, MacDougall EJ, Alluli A, Goldsmith TM, Schneider A, Dorion S, Aprahamian N, MacDonald A, Thomas RA, Dudley RWR, Hall JA, Fon EA, Antel JP, Stratton JA, Durcan TM, La Piana R, Healy LM. Dorion MF, et al. Among authors: durcan tm. Mol Neurodegener. 2024 Apr 5;19(1):31. doi: 10.1186/s13024-024-00723-x. Mol Neurodegener. 2024. PMID: 38576039 Free PMC article.
Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins.
Xu T, Heon-Roberts R, Moore T, Dubot P, Pan X, Guo T, Cairo CW, Holley R, Bigger B, Durcan TM, Levade T, Ausseil J, Amilhon B, Gorelik A, Nagar B, Sturiale L, Palmigiano A, Röckle I, Thiesler H, Hildebrandt H, Garozzo D, Pshezhetsky AV. Xu T, et al. Among authors: durcan tm. bioRxiv [Preprint]. 2024 Apr 27:2024.04.26.587986. doi: 10.1101/2024.04.26.587986. bioRxiv. 2024. Update in: J Clin Invest. 2025 Jun 17;135(16):e177430. doi: 10.1172/JCI177430. PMID: 38712143 Free PMC article. Updated. Preprint.
14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation.
Rial SA, You Z, Vivoli A, Sean D, Al-Khoury A, Lavoie G, Civelek M, Martinez-Sanchez A, Roux Pp, Durcan TM, Lim GE. Rial SA, et al. Among authors: durcan tm. bioRxiv [Preprint]. 2024 Mar 19:2024.03.18.585495. doi: 10.1101/2024.03.18.585495. bioRxiv. 2024. Update in: Mol Metab. 2025 Jul;97:102159. doi: 10.1016/j.molmet.2025.102159. PMID: 38562727 Free PMC article. Updated. Preprint.
Digital image files in light microscopy.
Durcan TM, Hinchcliffe EH. Durcan TM, et al. Methods Cell Biol. 2007;81:315-33. doi: 10.1016/S0091-679X(06)81015-0. Methods Cell Biol. 2007. PMID: 17519173 Review. No abstract available.
119 results