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Page 1
Pharmacometabolomics applied to low-dose interleukin-2 treatment in amyotrophic lateral sclerosis.
Alarcan H, Bruno C, Emond P, Raoul C, Vourc'h P, Corcia P, Camu W, Veyrune JL, Garlanda C, Locati M, Juntas-Morales R, Saker S, Suehs C, Masseguin C, Kirby J, Shaw P, Malaspina A, De Vos J, Al-Chalabi A, Leigh PN, Tree T, Bensimon G, Blasco H. Alarcan H, et al. Among authors: tree t. Ann N Y Acad Sci. 2024 Jun;1536(1):82-91. doi: 10.1111/nyas.15147. Epub 2024 May 21. Ann N Y Acad Sci. 2024. PMID: 38771698 Clinical Trial.
Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial.
Bensimon G, Leigh PN, Tree T, Malaspina A, Payan CA, Pham HP, Klaassen P, Shaw PJ, Al Khleifat A, Amador MDM, Attarian S, Bell SM, Beltran S, Bernard E, Camu W, Corcia P, Corvol JC, Couratier P, Danel V, Debs R, Desnuelle C, Dimitriou A, Ealing J, Esselin F, Fleury MC, Gorrie GH, Grapperon AM, Hesters A, Juntas-Morales R, Kolev I, Lautrette G, Le Forestier N, McDermott CJ, Pageot N, Salachas F, Sharma N, Soriani MH, Sreedharan J, Svahn J, Verber N, Verschueren A, Yildiz O, Suehs CM, Saker-Delye S, Muller C, Masseguin C, Hajduchova H, Kirby J, Garlanda C, Locati M, Zetterberg H, Asselain B, Al-Chalabi A; MIROCALS Study Group. Bensimon G, et al. Among authors: tree t. Lancet. 2025 May 24;405(10492):1837-1850. doi: 10.1016/S0140-6736(25)00262-4. Epub 2025 May 9. Lancet. 2025. PMID: 40354799 Free article. Clinical Trial.
Minimum effective low dose of antithymocyte globulin in people aged 5-25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.
Mathieu C, Wych J, Hendriks AEJ, Van Ryckeghem L, Tree T, Chmura P, Möller C, Casteels K, Danne T, Reschke F, Šmigoc Schweiger D, Battelino T, Johannesen J, Rami-Merhar B, Pieber T, De Block C, Evans M, Hilbrands R, Bosi E, Willemsen RH, Basu S, Pulkkinen MA, Knip M, Cnop M, Nitsche A, Schulte AM, Niemöller E, Peakman M, Wilhelm-Benartzi C, Gillespie D, Overbergh L, Mander AP, Marcovecchio ML; INNODIA. Mathieu C, et al. Among authors: tree t. Lancet. 2025 Sep 27;406(10510):1375-1388. doi: 10.1016/S0140-6736(25)01674-5. Epub 2025 Sep 18. Lancet. 2025. PMID: 40976248 Clinical Trial.
Blood samples collected under anesthesia can be used as a source of non-diseased controls for immune-based assays.
Domingo-Vila C, Williams ED, Smithmyer ME, Benson B, Ferrat LA, Arif S, Hudson M, Dobbs B, Johnson MB, Yardley I, Speake C, Oram RA, Tree TIM, Blaise BJ; EXE-T1D consortium. Domingo-Vila C, et al. Among authors: tree tim. Front Immunol. 2025 Jul 24;16:1618080. doi: 10.3389/fimmu.2025.1618080. eCollection 2025. Front Immunol. 2025. PMID: 40777034 Free PMC article.
Clonal driver neoantigen loss under EGFR TKI and immune selection pressures.
Al Bakir M, Reading JL, Gamble S, Rosenthal R, Uddin I, Rowan A, Przewrocka J, Rogers A, Wong YNS, Bentzen AK, Veeriah S, Ward S, Garnett AT, Kalavakur P, Martínez-Ruiz C, Puttick C, Huebner A, Cook DE, Moore DA, Abbosh C, Hiley CT, Naceur-Lombardelli C, Watkins TBK, Petkovic M, Schwarz RF, Gálvez-Cancino F, Litchfield K, Meldgaard P, Sorensen BS, Madsen LB, Jäger D, Forster MD, Arkenau T, Domingo-Vila C, Tree TIM, Kadivar M, Hadrup SR, Chain B, Quezada SA, McGranahan N, Swanton C. Al Bakir M, et al. Among authors: tree tim. Nature. 2025 Mar;639(8056):1052-1059. doi: 10.1038/s41586-025-08586-y. Epub 2025 Feb 19. Nature. 2025. PMID: 39972134 Free PMC article.
Anti-viral action against type 1 diabetes autoimmunity: The GPPAD-AVAnT1A study protocol.
Hummel S, Käßl A, Arnolds S, Achenbach P, Berner R, Casteels K, Hyöty H, Kordonouri O, Larsson HE, Lundgren M, Marcovecchio ML, Owen C, Pfirrmann M, Robson S, Szadkowska A, Szypowska A, Tree T, Weiss A, Ziegler AG, Bonifacio E; GPPAD Study Group. Hummel S, et al. Among authors: tree t. Contemp Clin Trials Commun. 2025 Jan 20;44:101434. doi: 10.1016/j.conctc.2025.101434. eCollection 2025 Apr. Contemp Clin Trials Commun. 2025. PMID: 39916680 Free PMC article.
The efficacy and safety of ustekinumab in adolescents newly diagnosed with type 1 diabetes: the USTEK1D RCT.
Carter K, Cheung WY, Hutchings HA, Fegan G, Holland G, Luzio S, Dunseath G, Hiles S, Marques-Jones S, Gregory JW, Tatovic D, Taylor P, Bowen-Morris J, Stenson R, Hanna S, Mahmood Z, Yang J, Williams E, Tree T, Marwaha A, Dayan CM. Carter K, et al. Among authors: tree t. Southampton (UK): National Institute for Health and Care Research; 2025 Feb. Southampton (UK): National Institute for Health and Care Research; 2025 Feb. PMID: 39999241 Free Books & Documents. Review.
Meeting Report: The Sixth International Sam Strober Workshop on Clinical Immune Tolerance.
Stark H, Ho QY, Cross A, Alessandrini A, Bertaina A, Brennan D, Busque S, Demetris A, Devey L, Fruhwirth G, Fuchs E, Friend P, Geissler E, Guillonneau C, Hester J, Isaacs J, Jaeckel E, Kawai T, Lakkis F, Leventhal J, Levings M, Levitsky J, Lombardi G, Martinez-Llordella M, Mathew J, Moreau A, Reinke P, Riella LV, Sachs D, Fueyo AS, Schreeb K, Sykes M, Tang Q, Thomson A, Tree T, Trzonkowski P, Uchida K, Veale J, Weiner J, Wekerle T, Issa F. Stark H, et al. Among authors: tree t. Transplantation. 2025 Apr 1;109(4):569-579. doi: 10.1097/TP.0000000000005311. Epub 2025 Jan 13. Transplantation. 2025. PMID: 39800883 No abstract available.
111 results