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Multifaceted mitochondria in innate immunity.
Marques E, Kramer R, Ryan DG. Marques E, et al. NPJ Metab Health Dis. 2024;2(1):6. doi: 10.1038/s44324-024-00008-3. Epub 2024 May 27. NPJ Metab Health Dis. 2024. PMID: 38812744 Free PMC article. Review.
Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation.
Casey AM, Ryan DG, Prag HA, Chowdhury SR, Marques E, Turner K, Gruszczyk AV, Yang M, Wolf DM, Miljkovic JL, Valadares J, Chinnery PF, Hartley RC, Frezza C, Prudent J, Murphy MP. Casey AM, et al. Among authors: marques e. Nat Metab. 2025 Mar;7(3):493-507. doi: 10.1038/s42255-025-01224-x. Epub 2025 Feb 19. Nat Metab. 2025. PMID: 39972217 Free PMC article.
An inherited mitochondrial DNA mutation remodels inflammatory cytokine responses in macrophages and in vivo in mice.
Marques E, Burr SP, Casey AM, Stopforth RJ, Yu CS, Turner K, Wolf DM, Dilucca M, Paupe V, Chowdhury SR, Tyrrell VJ, Kramer R, Kanse YM, Pednekar C, Powell CA, Stewart JB, Prudent J, Murphy MP, Minczuk M, O'Donnell VB, Bryant CE, Chinnery PF, Kaser A, von Kriegsheim A, Ryan DG. Marques E, et al. Nat Commun. 2025 Nov 20;16(1):10222. doi: 10.1038/s41467-025-65023-4. Nat Commun. 2025. PMID: 41266309 Free PMC article.
Host genetic ancestry and immunity to pathogens.
Castanha PMS, Martí MM, Marques ETA, Martinson JJ, Barratt-Boyes SM. Castanha PMS, et al. Among authors: marques eta. Trends Microbiol. 2026 Mar 23:S0966-842X(26)00033-8. doi: 10.1016/j.tim.2026.02.007. Online ahead of print. Trends Microbiol. 2026. PMID: 41876293 Review.
1,058 results