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Zoliflodacin versus ceftriaxone plus azithromycin for treatment of uncomplicated urogenital gonorrhoea: an international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial.
Luckey A, Balasegaram M, Barbee LA, Batteiger TA, Broadhurst H, Cohen SE, Delany-Moretlwe S, de Vries HJC, Dionne JA, Gill K, Kenyon C, Kittiyaowamarn R, Lewis D, Mueller JP, Naicker V, O'Brien S, O'Donnell JP, Phanuphak N, Spooner E, Srinivasan S, Taylor SN, Unemo M, Zwane Z, Hook EW 3rd; Zoliflodacin Phase 3 Study Group. Luckey A, et al. Among authors: hook ew 3rd. Lancet. 2025 Dec 11:S0140-6736(25)01953-1. doi: 10.1016/S0140-6736(25)01953-1. Online ahead of print. Lancet. 2025. PMID: 41391465 Free article.
One Dose versus Three Doses of Benzathine Penicillin G in Early Syphilis.
Hook EW 3rd, Dionne JA, Workowski K, McNeil CJ, Taylor SN, Batteiger TA, Dombrowski JC, Mayer KH, Seña AC, Hamill MM, Wiesenfeld HC, Zhu C, Perlowski C, Mejia-Galvis JE, Newman LM. Hook EW 3rd, et al. N Engl J Med. 2025 Sep 4;393(9):869-878. doi: 10.1056/NEJMoa2401802. N Engl J Med. 2025. PMID: 40902161 Clinical Trial.
Jarisch-Herxheimer Reaction After Benzathine Penicillin G Treatment in Adults With Early Syphilis: Secondary Analysis of a Randomized Clinical Trial.
Dionne JA, Zhu C, Mejia-Galvis J, Workowski K, Batteiger TA, Dombrowski JC, Mayer KH, McNeil CJ, Seña AC, Taylor S, Wiesenfeld HC, Hamill MM, Perlowski C, Hook EW 3rd. Dionne JA, et al. Among authors: hook ew 3rd. JAMA Netw Open. 2025 Feb 3;8(2):e2459490. doi: 10.1001/jamanetworkopen.2024.59490. JAMA Netw Open. 2025. PMID: 39946129 Free PMC article. Clinical Trial.
Near-Universal Resistance to Macrolides of Treponema pallidum in North America.
Lieberman NAP, Reid TB, Cannon CA, Nunley BE, Berzkalns A, Cohen SE, Newman LM, Aldrete S, Xu LH, Thornlund CP, Pettus K, Lundy S, Kron M, Soge OO, Workowski K, Perlowski C, Hook EW 3rd, Dionne JA, Golden MR, Lieberman JA, Lee MK, Morshed M, Naidu P, Cao W, Pillay A, Giacani L, Greninger AL. Lieberman NAP, et al. Among authors: hook ew 3rd. N Engl J Med. 2024 Jun 13;390(22):2127-2128. doi: 10.1056/NEJMc2314441. N Engl J Med. 2024. PMID: 38865666 Free PMC article. No abstract available.
335 results