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PROTACs in platelets: emerging antithrombotic strategies and future perspectives.
Curr Opin Hematol. 2025 Jan 1;32(1):34-42. doi: 10.1097/MOH.0000000000000846. Epub 2024 Oct 18.
Curr Opin Hematol. 2025.
PMID: 39446364
Review.
Difluorinated thromboxane A2 reveals crosstalk between platelet activatory and inhibitory pathways by targeting both the TP and IP receptors.
Allen MF, Hutchinson JL, Keith M, Mallah S, Corey RA, Trory JS, Jing C, Fang H, Wei L, Bennett SH, Aggarwal VK, Mundell SJ, Hers I.
Allen MF, et al. Among authors: trory js.
Br J Pharmacol. 2024 Oct;181(19):3685-3699. doi: 10.1111/bph.16435. Epub 2024 Jun 5.
Br J Pharmacol. 2024.
PMID: 38840293
Free article.
Item in Clipboard
A 'click' chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras.
Cross JM, Coulson ME, Smalley JP, Pytel WA, Ismail O, Trory JS, Cowley SM, Hodgkinson JT.
Cross JM, et al. Among authors: trory js.
RSC Med Chem. 2022 Nov 1;13(12):1634-1639. doi: 10.1039/d2md00199c. eCollection 2022 Dec 14.
RSC Med Chem. 2022.
PMID: 36545434
Free PMC article.
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Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function.
Trory JS, Munkacsi A, Śledź KM, Vautrinot J, Goudswaard LJ, Jackson ML, Heesom KJ, Moore SF, Poole AW, Nabet B, Aggarwal VK, Hers I.
Trory JS, et al.
Blood Adv. 2023 May 9;7(9):1692-1696. doi: 10.1182/bloodadvances.2022008466.
Blood Adv. 2023.
PMID: 36342848
Free PMC article.
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