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Somatic RIT1 delins in arteriovenous malformations hyperactivate RAS-MAPK signaling amenable to MEK inhibition.
Kapp FG, Bazgir F, Mahammadzade N, Mehrabipour M, Vassella E, Bernhard SM, Döring Y, Holm A, Karow A, Seebauer C, Platz Batista da Silva N, Wohlgemuth WA, Oppenheimer A, Kröning P, Niemeyer CM, Schanze D, Zenker M, Eng W, Ahmadian MR, Baumgartner I, Rössler J. Kapp FG, et al. Among authors: seebauer c. Angiogenesis. 2024 Nov;27(4):739-752. doi: 10.1007/s10456-024-09934-8. Epub 2024 Jul 5. Angiogenesis. 2024. PMID: 38969873 Free PMC article.
Clinical Outcome and Quality of Life of Multimodal Treatment of Extracranial Arteriovenous Malformations: The APOLLON Study Protocol.
Schmidt VF, Masthoff M, Vielsmeier V, Seebauer CT, Cangir Ö, Meyer L, Mükke A, Lang W, Schmid A, Sporns PB, Brill R, Wohlgemuth WA, da Silva NPB, Seidensticker M, Schinner R, Küppers J, Häberle B, Haubner F, Ricke J, Zenker M, Kimm MA, Wildgruber M; APOLLON investigators. Schmidt VF, et al. Cardiovasc Intervent Radiol. 2023 Jan;46(1):142-151. doi: 10.1007/s00270-022-03296-8. Epub 2022 Oct 19. Cardiovasc Intervent Radiol. 2023. PMID: 36261507 Free PMC article.
Targeting the microenvironment in the treatment of arteriovenous malformations.
Seebauer CT, Wiens B, Hintschich CA, Platz Batista da Silva N, Evert K, Haubner F, Kapp FG, Wendl C, Renner K, Bohr C, Kühnel T, Vielsmeier V. Seebauer CT, et al. Angiogenesis. 2024 Feb;27(1):91-103. doi: 10.1007/s10456-023-09896-3. Epub 2023 Sep 21. Angiogenesis. 2024. PMID: 37733132 Free PMC article.
Extracranial Vascular Anomalies Driven by RAS/MAPK Variants: Spectrum and Genotype-Phenotype Correlations.
Schmidt VF, Kapp FG, Goldann C, Huthmann L, Cucuruz B, Brill R, Vielsmeier V, Seebauer CT, Michel AJ, Seidensticker M, Uller W, Weiß JBW, Sint A, Häberle B, Haehl J, Wagner A, Cordes J, Holm A, Schanze D, Ricke J, Kimm MA, Wohlgemuth WA, Zenker M, Wildgruber M; APOLLON Investigators. Schmidt VF, et al. Among authors: seebauer ct. J Am Heart Assoc. 2024 Apr 16;13(8):e033287. doi: 10.1161/JAHA.123.033287. Epub 2024 Apr 2. J Am Heart Assoc. 2024. PMID: 38563363 Free PMC article.
Peritoneal carcinomatosis of colorectal cancer is characterized by structural and functional reorganization of the tumor microenvironment inducing senescence and proliferation arrest in cancer cells.
Seebauer CT, Brunner S, Glockzin G, Piso P, Ruemmele P, Schlitt HJ, Geissler EK, Fichtner-Feigl S, Kesselring R. Seebauer CT, et al. Oncoimmunology. 2016 Oct 14;5(12):e1242543. doi: 10.1080/2162402X.2016.1242543. eCollection 2016. Oncoimmunology. 2016. PMID: 28439450 Free PMC article.
57 results