A Common PD-Risk GBA1 Variant Disrupts LIMP2 Interaction, Impairs Glucocerebrosidase Function, and Drives Lysosomal and Mitochondrial Dysfunction.
Davis OB, Kung JE, Davis SS, Ghosh R, Andrews SV, Gould NS, Kluss JH, Thomsen E, Agam M, Coan JP, Maloney MT, Nguyen AH, Nguyen HN, Propson NE, Lozano EI, Yuan T, Xa K, Sperberg RAP, Jain S, Lawrence R, Ullman JC, Balasundar S, Benton HP, Petkovic M, Qerqez AN, Wang X, Zhu S, Di Paolo G, Kariolis MS, Mahon CS, Arguello A, Vocadlo DJ, Cookson MR, Suh JH, Rougé L, Henry AG.
Davis OB, et al. Among authors: davis ss.
bioRxiv [Preprint]. 2025 Sep 2:2025.08.28.672891. doi: 10.1101/2025.08.28.672891.
bioRxiv. 2025.
PMID: 41030976
Free PMC article.
Preprint.