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Page 1
Integrated omics reveals disease-associated radial glia-like cells with epigenetically dysregulated interferon response in multiple sclerosis.
Park B, Nicaise AM, Tsitsipatis D, Pirvan L, Zucha D, Munteanu A, Prasad P, De Novales MLL, Bulgaru C, Kollyfas R, Whitten J, Willis CM, Culig L, Llewellyn J, Ionescu RB, Mekdad M, Simões-Abade MBC, Krzak G, Fan J, De S, Ellis MO, Cubero MS, Spathopoulou A, Peruzzotti-Jametti L, Leonardi T, Balmus G, Edenhofer F, Gorospe M, Valihrach L, Mohorianu I, Pluchino S, Beerman I. Park B, et al. Among authors: tsitsipatis d. Neuron. 2025 Oct 10:S0896-6273(25)00710-X. doi: 10.1016/j.neuron.2025.09.022. Online ahead of print. Neuron. 2025. PMID: 41075785 Free article.
Senolytic treatment with fisetin reverses age-related endothelial dysfunction partially mediated by SASP factor CXCL12.
Mahoney SA, Mazan-Mamczarz K, Tsitsipatis D, VanDongen NS, Henry-Smith C, Okereke AN, Munk R, Darvish S, Murray KO, De S, Gorospe M, Seals DR, Rossman MJ, Herman AB, Clayton ZS. Mahoney SA, et al. Among authors: tsitsipatis d. bioRxiv [Preprint]. 2025 Aug 18:2025.08.13.670216. doi: 10.1101/2025.08.13.670216. bioRxiv. 2025. PMID: 40894771 Free PMC article. Preprint.
Pig Taste Cell-derived Organoids Synthesize Insulin.
Premathilake HU, Mazucanti CH, Yao Q, O'Connell JF, Vegesna N, Tsitsipatis D, Weller C, Lam KG, Candia J, Fan J, De S, Sen P, Egan JM, Doyle ME. Premathilake HU, et al. Among authors: tsitsipatis d. Endocrinology. 2025 Jul 8;166(9):bqaf126. doi: 10.1210/endocr/bqaf126. Endocrinology. 2025. PMID: 40755411
Plasma GDF15 affects long-term dementia risk and alters neuro-immune signaling.
Blew CO, Duggan MR, Tsitsipatis D, Gomez GT, Hernandez ZR, Pilling LC, Chen J, Jacobsen E, Dark HE, Lu Y, Drouin SM, Joynes CM, Yao M, Bilgel M, Moghekar A, Tian Q, Candia J, Kaileh M, Gupta A, Mazan-Mamczarz K, Gorospe M, Lyashkov A, Lukyanenko Y, Kivimaki M, Frank P, Jennings LL, Gudmundsdottir V, Gudnason V, Launer LJ, Kaneko N, Kato S, Furuichi M, Shibayama M, Katsuno M, Hiraga K, Nishita Y, Otsuka R, Pike JR, Rooney MR, Schlosser P, Cui Y, Erus G, Davatzikos C, Gottesman RF, Waga I, Palta P, Ballantyne C, Griswold M, Liu Z, Ferrucci L, Herman AB, Walker KA. Blew CO, et al. Among authors: tsitsipatis d. medRxiv [Preprint]. 2025 Jul 21:2025.07.18.25331297. doi: 10.1101/2025.07.18.25331297. medRxiv. 2025. PMID: 40735247 Free PMC article. Preprint.
Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice.
Mazan-Mamczarz K, Tsitsipatis D, Childs BG, Carr AE, Dos Santos CR, Anerillas C, Romero B, Gregg JM, Henry-Smith C, Okereke AN, Michel M, Munk R, Martindale JL, Piao Y, Fan J, Hernandez MO, Kedei N, Viacheslavov ML, Wong MMF, Fedorova OV, Batish M, De S, Baker DJ, Gorospe M, Herman AB. Mazan-Mamczarz K, et al. Among authors: tsitsipatis d. Nat Aging. 2025 Aug;5(8):1528-1547. doi: 10.1038/s43587-025-00889-z. Epub 2025 Jul 14. Nat Aging. 2025. PMID: 40660002 Free PMC article.
The secretome of senescent monocytes predicts age-related clinical outcomes in humans.
Olinger B, Banarjee R, Dey A, Tsitsipatis D, Tanaka T, Ram A, Nyunt T, Daya GN, Peng Z, Shrivastava M, Cui L, Candia J, Simonsick EM, Gorospe M, Walker KA, Ferrucci L, Basisty N. Olinger B, et al. Among authors: tsitsipatis d. Nat Aging. 2025 Jul;5(7):1266-1279. doi: 10.1038/s43587-025-00877-3. Epub 2025 Jun 3. Nat Aging. 2025. PMID: 40461807 Free PMC article.
49 results