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Glucagon-Producing Pancreatic Neuroendocrine Tumors (Glucagonomas) are Enriched in Aggressive Neoplasms with ARX and PDX1 Co-expression, DAXX/ATRX Mutations, and ALT (Alternative Lengthening of Telomeres).
Mattiolo P, Bevere M, Mafficini A, Verschuur AVD, Calicchia M, Hackeng WM, Simbolo M, Paiella S, Dreijerink KMA, Landoni L, Pedron S, Cingarlini S, Salvia R, Milella M, Lawlor RT, Valk GD, Vriens MR, Scarpa A, Brosens LA, Luchini C. Mattiolo P, et al. Among authors: hackeng wm. Endocr Pathol. 2024 Dec;35(4):354-361. doi: 10.1007/s12022-024-09826-z. Epub 2024 Sep 27. Endocr Pathol. 2024. PMID: 39331358 Free PMC article.
Clear cell chondrosarcoma in Von Hippel-Lindau disease.
Dreijerink KMA, van Leeuwaarde RS, Hackeng WM, Giles RH, de Leng WWJ, Jutte PC, Suurmeijer AJH, van Nesselrooij BPM, Brosens LAA. Dreijerink KMA, et al. Among authors: hackeng wm. Fam Cancer. 2020 Jan;19(1):41-45. doi: 10.1007/s10689-019-00149-1. Fam Cancer. 2020. PMID: 31673890 Free PMC article.
Genomic characterization of malignant progression in neoplastic pancreatic cysts.
Noë M, Niknafs N, Fischer CG, Hackeng WM, Beleva Guthrie V, Hosoda W, Debeljak M, Papp E, Adleff V, White JR, Luchini C, Pea A, Scarpa A, Butturini G, Zamboni G, Castelli P, Hong SM, Yachida S, Hiraoka N, Gill AJ, Samra JS, Offerhaus GJA, Hoorens A, Verheij J, Jansen C, Adsay NV, Jiang W, Winter J, Albores-Saavedra J, Terris B, Thompson ED, Roberts NJ, Hruban RH, Karchin R, Scharpf RB, Brosens LAA, Velculescu VE, Wood LD. Noë M, et al. Among authors: hackeng wm. Nat Commun. 2020 Aug 14;11(1):4085. doi: 10.1038/s41467-020-17917-8. Nat Commun. 2020. PMID: 32796935 Free PMC article.
The Management of Neuroendocrine Tumors of the Lung in MEN1: Results From the Dutch MEN1 Study Group.
van den Broek MFM, de Laat JM, van Leeuwaarde RS, van de Ven AC, de Herder WW, Dekkers OM, Drent ML, Kerstens MN, Bisschop PH, Havekes B, Hackeng WM, Brosens LAA, Vriens MR, Buikhuisen WA, Valk GD. van den Broek MFM, et al. Among authors: hackeng wm. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e1014-e1027. doi: 10.1210/clinem/dgaa800. J Clin Endocrinol Metab. 2021. PMID: 33135721
Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size.
Hackeng WM, Brosens LAA, Kim JY, O'Sullivan R, Sung YN, Liu TC, Cao D, Heayn M, Brosnan-Cashman J, An S, Morsink FHM, Heidsma CM, Valk GD, Vriens MR, Nieveen van Dijkum E, Offerhaus GJA, Dreijerink KMA, Zeh H, Zureikat AH, Hogg M, Lee K, Geller D, Marsh JW, Paniccia A, Ongchin M, Pingpank JF, Bahary N, Aijazi M, Brand R, Chennat J, Das R, Fasanella KE, Khalid A, McGrath K, Sarkaria S, Singh H, Slivka A, Nalesnik M, Han X, Nikiforova MN, Lawlor RT, Mafficini A, Rusev B, Corbo V, Luchini C, Bersani S, Pea A, Cingarlini S, Landoni L, Salvia R, Milione M, Milella M, Scarpa A, Hong SM, Heaphy CM, Singhi AD. Hackeng WM, et al. Gut. 2022 May;71(5):961-973. doi: 10.1136/gutjnl-2020-322595. Epub 2021 Apr 13. Gut. 2022. PMID: 33849943 Free PMC article.
29 results