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Page 1
mRNA-based influenza vaccine expands breadth of B cell response in humans.
Matz HC, Yu TG, Zhou JQ, Peyton L, Madsen A, Han F, Schmitz AJ, Horvath SC, Dixit K, Keplinger HK, Strnad BS, Hoegger MJ, Middleton WD, Klebert MK, Lin NH, Nachbagauer R, Paris R, Turner JS, Presti RM, Lee J, Ellebedy AH. Matz HC, et al. Among authors: turner js. bioRxiv [Preprint]. 2024 Oct 13:2024.10.10.617255. doi: 10.1101/2024.10.10.617255. bioRxiv. 2024. PMID: 39416092 Free PMC article. Preprint.
The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies and targets both the NTD and the RBD.
Amanat F, Thapa M, Lei T, Sayed Ahmed SM, Adelsberg DC, Carreno JM, Strohmeier S, Schmitz AJ, Zafar S, Zhou JQ, Rijnink W, Alshammary H, Borcherding N, Reiche AG, Srivastava K, Sordillo EM, van Bakel H; Personalized Virology Initiative; Turner JS, Bajic G, Simon V, Ellebedy AH, Krammer F. Amanat F, et al. Among authors: turner js. medRxiv [Preprint]. 2021 May 1:2021.03.07.21253098. doi: 10.1101/2021.03.07.21253098. medRxiv. 2021. PMID: 33758878 Free PMC article. Preprint.
A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants.
Schmitz AJ, Turner JS, Liu Z, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Alsoussi WB, Case JB, Lei T, Thapa M, Amanat F, O'Halloran JA, Shi PY, Presti RM, Krammer F, Bajic G, Whelan SPJ, Diamond MS, Boon ACM, Ellebedy AH. Schmitz AJ, et al. Among authors: turner js. bioRxiv [Preprint]. 2021 Mar 24:2021.03.24.436864. doi: 10.1101/2021.03.24.436864. bioRxiv. 2021. Update in: Immunity. 2021 Sep 14;54(9):2159-2166.e6. doi: 10.1016/j.immuni.2021.08.013. PMID: 33791696 Free PMC article. Updated. Preprint.
Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination.
Kim W, Zhou JQ, Sturtz AJ, Horvath SC, Schmitz AJ, Lei T, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, Middleton WD, Teefey SA, Pusic I, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Kim W, et al. Among authors: turner js. bioRxiv [Preprint]. 2021 Nov 2:2021.10.31.466651. doi: 10.1101/2021.10.31.466651. bioRxiv. 2021. Update in: Nature. 2022 Apr;604(7904):141-145. doi: 10.1038/s41586-022-04527-1. PMID: 34751268 Free PMC article. Updated. Preprint.
SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Alsoussi WB, Malladi SK, Zhou JQ, Liu Z, Ying B, Kim W, Schmitz AJ, Lei T, Horvath SC, Sturtz AJ, McIntire KM, Evavold B, Han F, Scheaffer SM, Fox IF, Parra-Rodriguez L, Nachbagauer R, Nestorova B, Chalkias S, Farnsworth CW, Klebert MK, Pusic I, Strnad BS, Middleton WD, Teefey SA, Whelan SPJ, Diamond MS, Paris R, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Alsoussi WB, et al. Among authors: turner js. bioRxiv [Preprint]. 2022 Sep 22:2022.09.22.509040. doi: 10.1101/2022.09.22.509040. bioRxiv. 2022. Update in: Nature. 2023 May;617(7961):592-598. doi: 10.1038/s41586-023-06025-4. PMID: 36172127 Free PMC article. Updated. Preprint.
SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response in primary antibody deficiency patients.
Lin FJ, Doss AMA, Davis-Adams HG, Adams LJ, Hanson CH, VanBlargan LA, Liang CY, Chen RE, Monroy JM, Wedner HJ, Kulczycki A, Mantia TL, O'Shaughnessy CC, Raju S, Zhao FR, Rizzi E, Rigell CJ, Dy TB, Kau AL, Ren Z, Turner JS, O'Halloran JA, Presti RM, Fremont DH, Kendall PL, Ellebedy AH, Mudd PA, Diamond MS, Zimmerman O, Laidlaw BJ. Lin FJ, et al. Among authors: turner js. Front Immunol. 2022 Dec 22;13:1033770. doi: 10.3389/fimmu.2022.1033770. eCollection 2022. Front Immunol. 2022. PMID: 36618402 Free PMC article.
Persons with HIV Develop Spike-Specific Lymph Node Germinal Center Responses following SARS-CoV-2 Vaccination.
Quinn M, Parra-Rodriguez L, Alsoussi WB, Ayres C, Klebert MK, Liu C, Suessen T, Scheaffer SM, Middleton WD, Teefey SA, Powderly WG, Diamond MS, Presti RM, Ellebedy AH, Turner JS, O'Halloran JA, Mudd PA. Quinn M, et al. Among authors: turner js. J Immunol. 2023 Apr 1;210(7):947-958. doi: 10.4049/jimmunol.2200920. J Immunol. 2023. PMID: 36779802 Free PMC article.
Spatiotemporal development of the human T follicular helper cell response to Influenza vaccination.
Schattgen SA, Turner JS, Ghonim MA, Crawford JC, Schmitz AJ, Kim H, Zhou JQ, Awad W, Kim W, McIntire KM, Haile A, Klebert MK, Suessen T, Middleton WD, Teefey SA, Presti RM, Ellebedy AH, Thomas PG. Schattgen SA, et al. Among authors: turner js. bioRxiv [Preprint]. 2023 Aug 31:2023.08.29.555186. doi: 10.1101/2023.08.29.555186. bioRxiv. 2023. Update in: Nat Immunol. 2024 Sep;25(9):1742-1753. doi: 10.1038/s41590-024-01926-6. PMID: 37693531 Free PMC article. Updated. Preprint.
Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.
Lei R, Kim W, Lv H, Mou Z, Scherm MJ, Schmitz AJ, Turner JS, Tan TJC, Wang Y, Ouyang WO, Liang W, Rivera-Cardona J, Teo C, Graham CS, Brooke CB, Presti RM, Mok CKP, Krammer F, Dai X, Ellebedy AH, Wu NC. Lei R, et al. Among authors: turner js. Immunity. 2023 Nov 14;56(11):2621-2634.e6. doi: 10.1016/j.immuni.2023.10.005. Immunity. 2023. PMID: 37967533 Free PMC article.
Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI.
Lopatto EDB, Santiago-Borges JM, Sanick DA, Malladi SK, Azimzadeh PN, Timm MW, Fox IF, Schmitz AJ, Turner JS, Ahmed SS, Ortinau L, Gualberto NC, Pinkner JS, Dodson KW, Ellebedy AH, Kau AL, Hultgren SJ. Lopatto EDB, et al. Among authors: turner js. bioRxiv [Preprint]. 2024 Dec 11:2024.12.10.627638. doi: 10.1101/2024.12.10.627638. bioRxiv. 2024. Update in: Sci Adv. 2025 Jun 20;11(25):eadw0698. doi: 10.1126/sciadv.adw0698. PMID: 39713358 Free PMC article. Updated. Preprint.
197 results