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Page 1
Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial.
Huppert LA, Wolf D, Yau C, Brown-Swigart L, Hirst GL, Isaacs C, Pusztai L, Pohlmann PR, DeMichele A, Shatsky R, Yee D, Thomas A, Nanda R, Perlmutter J, Heditsian D, Hylton N, Symmans F, Van't Veer LJ, Esserman L, Rugo HS. Huppert LA, et al. Among authors: perlmutter j. Ann Oncol. 2025 Feb;36(2):172-184. doi: 10.1016/j.annonc.2024.10.018. Epub 2024 Oct 28. Ann Oncol. 2025. PMID: 39477071 Free PMC article. Clinical Trial.
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.
Gallagher RI, Wulfkuhle J, Wolf DM, Brown-Swigart L, Yau C, O'Grady N, Basu A, Lu R, Campbell MJ, Magbanua MJ, Coppé JP; I-SPY 2 Investigators; Asare SM, Sit L, Matthews JB, Perlmutter J, Hylton N, Liu MC, Symmans WF, Rugo HS, Isaacs C, DeMichele AM, Yee D, Pohlmann PR, Hirst GL, Esserman LJ, van 't Veer LJ, Petricoin EF. Gallagher RI, et al. Among authors: perlmutter j. Cell Rep Med. 2023 Dec 19;4(12):101312. doi: 10.1016/j.xcrm.2023.101312. Epub 2023 Dec 11. Cell Rep Med. 2023. PMID: 38086377 Free PMC article.
Outcomes and clinicopathologic characteristics associated with disseminated tumor cells in bone marrow after neoadjuvant chemotherapy in high-risk early stage breast cancer: the I-SPY SURMOUNT study.
Magbanua MJM, van 't Veer L, Clark AS, Chien AJ, Boughey JC, Han HS, Wallace A, Beckwith H, Liu MC, Yau C, Wileyto EP, Ordonez A, Solanki TI, Hsiao F, Lee JC, Basu A, Brown Swigart L, Perlmutter J, Delson AL, Bayne L, Deluca S, Yee SS, Carpenter EL, Esserman LJ, Park JW, Chodosh LA, DeMichele A. Magbanua MJM, et al. Among authors: perlmutter j. Breast Cancer Res Treat. 2023 Apr;198(2):383-390. doi: 10.1007/s10549-022-06803-0. Epub 2023 Jan 23. Breast Cancer Res Treat. 2023. PMID: 36689092 Free PMC article.
Cholinergic dysfunction in occupational manganese exposure.
Hutson TN, Nielsen SS, Senini N, O'Donnell J, Flores HP, Hershey T, Perlmutter JS, Soda AK, Moerlein SM, Tu Z, Kasper M, Sheppard L, Racette BA, Criswell SR. Hutson TN, et al. Among authors: perlmutter js. Neurotoxicology. 2025 Sep 3;111:103313. doi: 10.1016/j.neuro.2025.103313. Online ahead of print. Neurotoxicology. 2025. PMID: 40912474 Free article.
Impact of Time to Surgery Post Neoadjuvant Chemotherapy on Breast Cancer Outcomes: A Retrospective Study of Patients Enrolled in the I-SPY 2 Clinical Trial.
Van Hassel J, Dimitroff K, Yau C, Mukhtar R, Boughey JC, Ladores V, Howard-McNatt MM, Jaskowiak N, Perlmutter J, DeMichele A, Yee D, Hylton N, Symmans WF, Veer LV, Rugo H, Esserman LJ, Shatsky R, Isaacs C, Kuerer H, Wallace AM, Prionas N, Tseng J, Reyna CR, Taunk N, Kesmodel S, Lee MC, Fox J, Piltin MA, Tchou J, Arciero CA, Postlewait LM, Sauder C, Rao R. Van Hassel J, et al. Among authors: perlmutter j. Ann Surg Oncol. 2025 Aug 23. doi: 10.1245/s10434-025-17933-2. Online ahead of print. Ann Surg Oncol. 2025. PMID: 40849380
Pilot Study of [11C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer.
Hsieh CJ, Saturnino Guarino D, Young AJ, Siderowf AD, Nasrallah I, Schmitz A, Garcia C, Kim HY, Schubert EK, Lee H, Perlmutter JS, Mach RH. Hsieh CJ, et al. Among authors: perlmutter js. Cells. 2025 Jul 26;14(15):1157. doi: 10.3390/cells14151157. Cells. 2025. PMID: 40801590 Free PMC article.
Using expert-cited features to detect leg dystonia in cerebral palsy.
Bajpai R, Rust A, Lott E, Kim S, Gandham S, Chintalapati K, Blackburn J, Gelineau-Morel R, Kruer MC, Mingbunjerdsuk D, O'Malley J, Tochen L, Waugh JL, Wu S, Feyma T, Perlmutter JS, Aravamuthan BR. Bajpai R, et al. Among authors: perlmutter js. medRxiv [Preprint]. 2025 Jul 18:2024.10.15.24315574. doi: 10.1101/2024.10.15.24315574. medRxiv. 2025. PMID: 40791730 Free PMC article. Preprint.
690 results