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De novo design of peptide binders to conformationally diverse targets with contrastive language modeling.
Bhat S, Palepu K, Hong L, Mao J, Ye T, Iyer R, Zhao L, Chen T, Vincoff S, Watson R, Wang TZ, Srijay D, Kavirayuni VS, Kholina K, Goel S, Vure P, Deshpande AJ, Soderling SH, DeLisa MP, Chatterjee P. Bhat S, et al. Among authors: soderling sh. Sci Adv. 2025 Jan 24;11(4):eadr8638. doi: 10.1126/sciadv.adr8638. Epub 2025 Jan 22. Sci Adv. 2025. PMID: 39841846 Free PMC article.
PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation.
Wang S, Baumert R, Séjourné G, Bindu DS, Dimond K, Sakers K, Vazquez L, Moore JL, Tan CX, Takano T, Rodriguez MP, Brose N, Bradley L, Lessing R, Soderling SH, La Spada AR, Eroglu C. Wang S, et al. Among authors: soderling sh. bioRxiv [Preprint]. 2025 Apr 25:2023.04.09.536178. doi: 10.1101/2023.04.09.536178. bioRxiv. 2025. PMID: 39253496 Free PMC article. Preprint.
De Novo Design of Peptide Binders to Conformationally Diverse Targets with Contrastive Language Modeling.
Bhat S, Palepu K, Hong L, Mao J, Ye T, Iyer R, Zhao L, Chen T, Vincoff S, Watson R, Wang T, Srijay D, Kavirayuni VS, Kholina K, Goel S, Vure P, Desphande AJ, Soderling SH, DeLisa MP, Chatterjee P. Bhat S, et al. Among authors: soderling sh. bioRxiv [Preprint]. 2024 Jul 22:2023.06.26.546591. doi: 10.1101/2023.06.26.546591. bioRxiv. 2024. Update in: Sci Adv. 2025 Jan 24;11(4):eadr8638. doi: 10.1126/sciadv.adr8638. PMID: 39091799 Free PMC article. Updated. Preprint.
62 results