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Page 1
IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma.
Karakousi T, Cristaldi V, Lopes de Oliveira ML, Delclaux I, Besson NR, Geraldo LH, González-Robles TJ, McDonnough DR, Martinez-Krams D, da Silva G, Breazeale AP, Encarnacion-Rosado J, Pozniak J, Qiu S, Illa Bochaca I, Kaiza ME, Kim HM, Bruno TC, Reizis B, Moshiri AS, Kimmelman AC, Ruggles KV, Osman I, Marine JC, Chandel NS, Lund AW. Karakousi T, et al. Among authors: besson nr. Cancer Cell. 2026 Jan 22:S1535-6108(25)00553-7. doi: 10.1016/j.ccell.2025.12.019. Online ahead of print. Cancer Cell. 2026. PMID: 41576931
CRATER tumor niches facilitate CD8+ T cell engagement and correspond with immunotherapy success.
Ludin A, Stirtz GL, Tal A, Nirmal AJ, Pfaff KL, Manos M, Besson N, Eskndir N, Porter B, Jones SM, Faulkner HM, Gong Q, Liu S, Barrera I, Wu L, Pessoa Rodrigues C, Sahu A, Jerison E, Alessi JV, Ricciuti B, Richardson DS, Weiss JD, Moreau HM, Stanhope ME, Afeyan AB, Sefton J, McCall WD, Formato E, Yang S, Zhou Y, Hoytema van Konijnenburg DP, Cole HL, Cordova M, Deng L, Rajadhyaksha M, Quake SR, Awad MM, Chen F, Wucherpfennig KW, Sorger PK, Hodi FS, Rodig SJ, Murphy GF, Zon LI. Ludin A, et al. Among authors: besson n. Cell. 2025 Nov 26;188(24):6720-6736.e26. doi: 10.1016/j.cell.2025.09.021. Epub 2025 Oct 17. Cell. 2025. PMID: 41109214 Free PMC article.
A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma.
Zhao W, Nguyen TT, Bhagwat A, Kumar A, Giotti B, Kepecs B, Weirather JL, Mahadevan NR, Segerstolpe A, Dolasia K, Abdul-Ghafar J, Besson NR, Jones SM, Soong BY, Li C, Vigneau S, Slyper M, Wakiro I, Su MJ, Helvie K, Frangieh A, Jane-Valbuena J, Ashenberg O, Awad M, Rotem A, Bueno R, Rozenblatt-Rosen O, Pfaff K, Rodig S, Hata AN, Regev A, Johnson BE, Tsankov AM. Zhao W, et al. Among authors: besson nr. Nat Cancer. 2025 Nov;6(11):1857-1879. doi: 10.1038/s43018-025-01053-7. Epub 2025 Oct 7. Nat Cancer. 2025. PMID: 41057692 Free PMC article.
Cancer-specific innate and adaptive immune rewiring drives resistance to PD-1 blockade in classic Hodgkin lymphoma.
Paczkowska J, Tang M, Wright KT, Song L, Luu K, Shanmugam V, Welsh EL, Weirather JL, Besson N, Olszewski H, Porter BA, Pfaff KL, Redd RA, Cader FZ, Mandato E, Ouyang J, Calabretta E, Bai G, Lawton LN, Armand P, Rodig SJ, Liu XS, Shipp MA. Paczkowska J, et al. Among authors: besson n. Nat Commun. 2024 Dec 30;15(1):10740. doi: 10.1038/s41467-024-54512-7. Nat Commun. 2024. PMID: 39737927 Free PMC article.
Dual Immune Checkpoint Inhibition in Patients With Aggressive Thyroid Carcinoma: A Phase 2 Nonrandomized Clinical Trial.
Sehgal K, Pappa T, Shin KY, Schiantarelli J, Liu M, Ricker C, Besson NR, Jones SM, Welsh EL, Pfaff KL, Barletta JA, Park J, Reardon B, Doherty GM, Alexander EK, Rodig SJ, Barbie DA, O'Neill A, Van Allen E, Haddad RI, Lorch JH. Sehgal K, et al. Among authors: besson nr. JAMA Oncol. 2024 Dec 1;10(12):1663-1671. doi: 10.1001/jamaoncol.2024.4019. JAMA Oncol. 2024. PMID: 39446365 Free PMC article. Clinical Trial.
Craters on the melanoma surface facilitate tumor-immune interactions and demonstrate pathologic response to checkpoint blockade in humans.
Ludin A, Stirtz GL, Tal A, Nirmal AJ, Besson N, Jones SM, Pfaff KL, Manos M, Liu S, Barrera I, Gong Q, Rodrigues CP, Sahu A, Jerison E, Alessi JV, Ricciuti B, Richardson DS, Weiss JD, Moreau HM, Stanhope ME, Afeyan AB, Sefton J, McCall WD, Formato E, Yang S, Zhou Y, van Konijnenburg DPH, Cole HL, Cordova M, Deng L, Rajadhyaksha M, Quake SR, Awad MM, Chen F, Sorger PK, Hodi FS, Rodig SJ, Murphy GF, Zon LI. Ludin A, et al. Among authors: besson n. bioRxiv [Preprint]. 2024 Sep 19:2024.09.18.613595. doi: 10.1101/2024.09.18.613595. bioRxiv. 2024. Update in: Cell. 2025 Nov 26;188(24):6720-6736.e26. doi: 10.1016/j.cell.2025.09.021. PMID: 39345527 Free PMC article. Updated. Preprint.
Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors.
Hoffman SE, Dowrey TW, Villacorta Martin C, Bi K, Titchen B, Johri S, DelloStritto L, Patel M, Mackichan C, Inga S, Chen J, Grimaldi G, Napolitano S, Wakiro I, Wu J, Yeung J, Rotem A, Sicinska E, Shannon E, Clancy T, Wang J, Denning S, Brais L, Besson NR, Pfaff KL, Huang Y, Kao KZ, Rodig S, Hornick JL, Vigneau S, Park J, Kulke MH, Chan J, Van Allen EM, Murphy GJ. Hoffman SE, et al. Among authors: besson nr. Sci Adv. 2023 Sep 29;9(39):eadd9668. doi: 10.1126/sciadv.add9668. Epub 2023 Sep 27. Sci Adv. 2023. PMID: 37756410 Free PMC article.
A cellular and spatial atlas of TP53 -associated tissue remodeling in lung adenocarcinoma.
Zhao W, Kepecs B, Mahadevan NR, Segerstolpe A, Weirather JL, Besson NR, Giotti B, Soong BY, Li C, Vigneau S, Slyper M, Wakiro I, Jane-Valbuena J, Ashenberg O, Rotem A, Bueno R, Rozenblatt-Rosen O, Pfaff K, Rodig S, Hata AN, Regev A, Johnson BE, Tsankov AM. Zhao W, et al. Among authors: besson nr. bioRxiv [Preprint]. 2024 Feb 14:2023.06.28.546977. doi: 10.1101/2023.06.28.546977. bioRxiv. 2024. Update in: Nat Cancer. 2025 Nov;6(11):1857-1879. doi: 10.1038/s43018-025-01053-7. PMID: 37425718 Free PMC article. Updated. Preprint.
Search for Dark Matter Produced in Association with a Dark Higgs Boson Decaying into W^{±}W^{∓} or ZZ in Fully Hadronic Final States from sqrt[s]=13  TeV pp Collisions Recorded with the ATLAS Detector.
Aad G, Abbott B, Abbott DC, Abed Abud A, Abeling K, Abhayasinghe DK, Abidi SH, AbouZeid OS, Abraham NL, Abramowicz H, Abreu H, Abulaiti Y, Acharya BS, Achkar B, Adam L, Adam Bourdarios C, Adamczyk L, Adamek L, Adelman J, Adiguzel A, Adorni S, Adye T, Affolder AA, Afik Y, Agapopoulou C, Agaras MN, Aggarwal A, Agheorghiesei C, Aguilar-Saavedra JA, Ahmad A, Ahmadov F, Ahmed WS, Ai X, Aielli G, Akatsuka S, Akbiyik M, Åkesson TPA, Akilli E, Akimov AV, Al Khoury K, Alberghi GL, Albert J, Alconada Verzini MJ, Alderweireldt S, Aleksa M, Aleksandrov IN, Alexa C, Alexopoulos T, Alfonsi A, Alfonsi F, Alhroob M, Ali B, Ali S, Aliev M, Alimonti G, Allaire C, Allbrooke BMM, Allen BW, Allport PP, Aloisio A, Alonso F, Alpigiani C, Alunno Camelia E, Alvarez Estevez M, Alviggi MG, Amaral Coutinho Y, Ambler A, Ambroz L, Amelung C, Amidei D, Amor Dos Santos SP, Amoroso S, Amrouche CS, An F, Anastopoulos C, Andari N, Andeen T, Anders JK, Andrean SY, Andreazza A, Andrei V, Anelli CR, Angelidakis S, Angerami A, Anisenkov AV, Annovi A, Antel C, Anthony MT, Antipov E, Antonelli M, Antrim DJA, Anulli F, Aoki M, Aparisi Pozo JA, Aparo MA, Aperio Bella L, Aranzabal N, Araujo Ferraz V, Araujo Pereira R, Arcan… See abstract for full author list ➔ Aad G, et al. Among authors: besson n. Phys Rev Lett. 2021 Mar 26;126(12):121802. doi: 10.1103/PhysRevLett.126.121802. Phys Rev Lett. 2021. PMID: 33834820 Free article.
269 results