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Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood-brain barrier model.
Mészáros M, Phan THM, Vigh JP, Porkoláb G, Kocsis A, Szecskó A, Páli EK, Cser NM, Polgár TF, Kecskeméti G, Walter FR, Schwamborn JC, Janáky T, Jan JS, Veszelka S, Deli MA. Mészáros M, et al. Among authors: jan js. Fluids Barriers CNS. 2025 Feb 19;22(1):18. doi: 10.1186/s12987-025-00623-2. Fluids Barriers CNS. 2025. PMID: 39972353 Free PMC article.
A Triple Combination of Targeting Ligands Increases the Penetration of Nanoparticles across a Blood-Brain Barrier Culture Model.
Veszelka S, Mészáros M, Porkoláb G, Szecskó A, Kondor N, Ferenc G, Polgár TF, Katona G, Kóta Z, Kelemen L, Páli T, Vigh JP, Walter FR, Bolognin S, Schwamborn JC, Jan JS, Deli MA. Veszelka S, et al. Among authors: jan js. Pharmaceutics. 2021 Dec 30;14(1):86. doi: 10.3390/pharmaceutics14010086. Pharmaceutics. 2021. PMID: 35056983 Free PMC article.
Targeting Human Endothelial Cells with Glutathione and Alanine Increases the Crossing of a Polypeptide Nanocarrier through a Blood-Brain Barrier Model and Entry to Human Brain Organoids.
Mészáros M, Phan THM, Vigh JP, Porkoláb G, Kocsis A, Páli EK, Polgár TF, Walter FR, Bolognin S, Schwamborn JC, Jan JS, Deli MA, Veszelka S. Mészáros M, et al. Among authors: jan js. Cells. 2023 Feb 3;12(3):503. doi: 10.3390/cells12030503. Cells. 2023. PMID: 36766845 Free PMC article.
Synergistic induction of blood-brain barrier properties.
Porkoláb G, Mészáros M, Szecskó A, Vigh JP, Walter FR, Figueiredo R, Kálomista I, Hoyk Z, Vizsnyiczai G, Gróf I, Jan JS, Gosselet F, Pirity MK, Vastag M, Hudson N, Campbell M, Veszelka S, Deli MA. Porkoláb G, et al. Among authors: jan js. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2316006121. doi: 10.1073/pnas.2316006121. Epub 2024 May 15. Proc Natl Acad Sci U S A. 2024. PMID: 38748577 Free PMC article.
116 results