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Page 1
Phosphatidylserine as a tumor target for CAR-T cell therapy.
Martín-Otal C, Sánchez-Moreno I, Gómez-Morón A, Castro C, Casares N, Navarro F, Gorraiz M, Justicia-Lirio P, Pareja F, Collantes M, Peñuelas I, Iñarrairaegui M, Sangro B, Vivas I, Larrayoz M, Rodriguez JR, Prosper F, Hervas-Stubbs S, Martin-Cofreces N, Lasarte JJ, Lozano T. Martín-Otal C, et al. Among authors: larrayoz m. J Immunother Cancer. 2025 Feb 23;13(2):e009468. doi: 10.1136/jitc-2024-009468. J Immunother Cancer. 2025. PMID: 39988346 Free PMC article.
Endogenous Retroelement Activation by Epigenetic Therapy Reverses the Warburg Effect and Elicits Mitochondrial-Mediated Cancer Cell Death.
Fresquet V, Garcia-Barchino MJ, Larrayoz M, Celay J, Vicente C, Fernandez-Galilea M, Larrayoz MJ, Calasanz MJ, Panizo C, Junza A, Han J, Prior C, Fortes P, Pio R, Oyarzabal J, Martinez-Baztan A, Paiva B, Moreno-Aliaga MJ, Odero MD, Agirre X, Yanes O, Prosper F, Martinez-Climent JA. Fresquet V, et al. Among authors: larrayoz m, larrayoz mj. Cancer Discov. 2021 May;11(5):1268-1285. doi: 10.1158/2159-8290.CD-20-1065. Epub 2020 Dec 18. Cancer Discov. 2021. PMID: 33355179
Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma.
Larrayoz M, Garcia-Barchino MJ, Celay J, Etxebeste A, Jimenez M, Perez C, Ordoñez R, Cobaleda C, Botta C, Fresquet V, Roa S, Goicoechea I, Maia C, Lasaga M, Chesi M, Bergsagel PL, Larrayoz MJ, Calasanz MJ, Campos-Sanchez E, Martinez-Cano J, Panizo C, Rodriguez-Otero P, Vicent S, Roncador G, Gonzalez P, Takahashi S, Katz SG, Walensky LD, Ruppert SM, Lasater EA, Amann M, Lozano T, Llopiz D, Sarobe P, Lasarte JJ, Planell N, Gomez-Cabrero D, Kudryashova O, Kurilovich A, Revuelta MV, Cerchietti L, Agirre X, San Miguel J, Paiva B, Prosper F, Martinez-Climent JA. Larrayoz M, et al. Among authors: larrayoz mj. Nat Med. 2023 Mar;29(3):632-645. doi: 10.1038/s41591-022-02178-3. Epub 2023 Mar 16. Nat Med. 2023. PMID: 36928817 Free PMC article.
Metabolization of microbial postbiotic pentanoate drives anti-cancer CAR T cells.
Staudt S, Nikolka F, Perl M, Franz J, Leblay N, Yuan XK, Larrayoz M, Lozano T, Warmuth L, Fante MA, Skorpskaite A, Fei T, Bromberg M, San Martin-Uriz P, Rodriguez-Madoz JR, Ziegler-Martin K, Adil-Gholam N, Benz P, Tran Huu P, Freitag F, Riester Z, Stein-Thoeringer C, Schmitt M, Kleigrewe K, Weber J, Mangold K, Ho P, Einsele H, Prosper F, Ellmeier W, Busch D, Visekruna A, Slingerland J, Shouval R, Hiller K, Lasarte JJ, Martinez-Climent JA, Pausch P, Neri P, van den Brink M, Poeck H, Hudecek M, Luu M. Staudt S, et al. Among authors: larrayoz m. bioRxiv [Preprint]. 2025 Feb 4:2024.08.19.608538. doi: 10.1101/2024.08.19.608538. bioRxiv. 2025. PMID: 39314273 Free PMC article. Preprint.
Reprogramming glutamine metabolism enhances BCMA-CART cell fitness and therapeutic efficacy in multiple myeloma.
Navarro F, Lozano T, Fuentes-García A, Sánchez-Moreno I, Larrayoz M, Justicia P, Perucha B, Martinez-Tabar M, Martinez-Turrillas R, Casares N, Martín-Otal C, Gorraiz M, Meermeier EW, Chesi M, Lake D, Bergsagel PL, Santamaría E, Calleja-Cervantes ME, San Martín-Úriz P, Jordana-Urriza L, Agirre X, Hervas-Stubbs S, Rodriguez-Madoz JR, Martínez-Climent JA, Prosper F, Lasarte JJ. Navarro F, et al. Among authors: larrayoz m. Blood. 2025 Sep 19:blood.2024027496. doi: 10.1182/blood.2024027496. Online ahead of print. Blood. 2025. PMID: 40971494
Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia.
García-Barchino MJ, Sarasquete ME, Panizo C, Morscio J, Martinez A, Alcoceba M, Fresquet V, Gonzalez-Farre B, Paiva B, Young KH, Robles EF, Roa S, Celay J, Larrayoz M, Rossi D, Gaidano G, Montes-Moreno S, Piris MA, Balanzategui A, Jimenez C, Rodriguez I, Calasanz MJ, Larrayoz MJ, Segura V, Garcia-Muñoz R, Rabasa MP, Yi S, Li J, Zhang M, Xu-Monette ZY, Puig-Moron N, Orfao A, Böttcher S, Hernandez-Rivas JM, Miguel JS, Prosper F, Tousseyn T, Sagaert X, Gonzalez M, Martinez-Climent JA. García-Barchino MJ, et al. Among authors: larrayoz m, larrayoz mj. J Pathol. 2018 May;245(1):61-73. doi: 10.1002/path.5060. Epub 2018 Mar 30. J Pathol. 2018. PMID: 29464716
Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma.
Valencia K, Sainz C, Bértolo C, de Biurrun G, Agorreta J, Azpilikueta A, Larrayoz M, Bosco G, Zandueta C, Redrado M, Redín E, Exposito F, Serrano D, Echepare M, Ajona D, Melero I, Pio R, Thomas R, Calvo A, Montuenga LM. Valencia K, et al. Among authors: larrayoz m. Dis Model Mech. 2022 Jan 1;15(1):dmm049137. doi: 10.1242/dmm.049137. Epub 2022 Jan 31. Dis Model Mech. 2022. PMID: 34870316 Free PMC article.
Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma.
Rodriguez S, Celay J, Goicoechea I, Jimenez C, Botta C, Garcia-Barchino MJ, Garces JJ, Larrayoz M, Santos S, Alignani D, Vilas-Zornoza A, Perez C, Garate S, Sarvide S, Lopez A, Reinhardt HC, Carrasco YR, Sanchez-Garcia I, Larrayoz MJ, Calasanz MJ, Panizo C, Prosper F, Lamo-Espinosa JM, Motta M, Tucci A, Sacco A, Gentile M, Duarte S, Vitoria H, Geraldes C, Paiva A, Puig N, Garcia-Sanz R, Roccaro AM, Fuerte G, San Miguel JF, Martinez-Climent JA, Paiva B. Rodriguez S, et al. Among authors: larrayoz m, larrayoz mj. Sci Adv. 2022 Jan 21;8(3):eabl4644. doi: 10.1126/sciadv.abl4644. Epub 2022 Jan 19. Sci Adv. 2022. PMID: 35044826 Free PMC article.
Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
Pajares MJ, Agorreta J, Larrayoz M, Vesin A, Ezponda T, Zudaire I, Torre W, Lozano MD, Brambilla E, Brambilla C, Wistuba II, Behrens C, Timsit JF, Pio R, Field JK, Montuenga LM. Pajares MJ, et al. Among authors: larrayoz m. J Clin Oncol. 2012 Apr 1;30(10):1129-36. doi: 10.1200/JCO.2011.37.4231. Epub 2012 Feb 21. J Clin Oncol. 2012. PMID: 22355056 Free PMC article.
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