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Cleavable linkers in antibody-drug conjugates.
Bargh JD , Isidro-Llobet A , Parker JS , Spring DR . Bargh JD , et al. Among authors: spring dr. Chem Soc Rev. 2019 Aug 12;48(16):4361-4374. doi: 10.1039/c8cs00676h. Chem Soc Rev. 2019. PMID: 31294429 Review.
Site-selective modification strategies in antibody-drug conjugates.
Walsh SJ , Bargh JD , Dannheim FM , Hanby AR , Seki H , Counsell AJ , Ou X , Fowler E , Ashman N , Takada Y , Isidro-Llobet A , Parker JS , Carroll JS , Spring DR . Walsh SJ , et al. Among authors: spring dr. Chem Soc Rev. 2021 Jan 21;50(2):1305-1353. doi: 10.1039/d0cs00310g. Epub 2020 Dec 8. Chem Soc Rev. 2021. PMID: 33290462 Review.
A dual-enzyme cleavable linker for antibody-drug conjugates.
Bargh JD , Walsh SJ , Ashman N , Isidro-Llobet A , Carroll JS , Spring DR . Bargh JD , et al. Among authors: spring dr. Chem Commun (Camb). 2021 Apr 11;57(28):3457-3460. doi: 10.1039/d1cc00957e. Epub 2021 Mar 9. Chem Commun (Camb). 2021. PMID: 33687404
Non-internalising antibody-drug conjugates.
Ashman N, Bargh JD, Spring DR. Ashman N, et al. Among authors: spring dr. Chem Soc Rev. 2022 Nov 14;51(22):9182-9202. doi: 10.1039/d2cs00446a. Chem Soc Rev. 2022. PMID: 36322071 Review.
Peroxide-cleavable linkers for antibody-drug conjugates.
Ashman N, Bargh JD, Walsh SJ, Greenwood RD, Tiberghien A, Carroll JS, Spring DR. Ashman N, et al. Among authors: spring dr. Chem Commun (Camb). 2023 Feb 9;59(13):1841-1844. doi: 10.1039/d2cc06677g. Chem Commun (Camb). 2023. PMID: 36722863 Free PMC article.
Advances in the Release of Amide-Containing Molecules.
Wharton T, Spring DR. Wharton T, et al. Among authors: spring dr. Chemistry. 2025 Mar 17;31(16):e202404413. doi: 10.1002/chem.202404413. Epub 2025 Jan 28. Chemistry. 2025. PMID: 39836098 Free PMC article.
233 results