Child SA - Search Results

1

Developing the evidence-base to inform policy on inclusive research design.

Child SA, Mulligan C, Pavlov I, Bryan S, Li L, Knowles RL. Child SA, et al. R Soc Open Sci. 2025 Mar 19;12(3):241380. doi: 10.1098/rsos.241380. eCollection 2025 Mar. R Soc Open Sci. 2025. PMID: 40109939 Free PMC article.

2

Structural determination and characterisation of the CYP105Q4 cytochrome P450 enzyme from Mycobacterium marinum.

Mohamed H, Child SA, Doherty DZ, Bruning JB, Bell SG. Mohamed H, et al. Among authors: child sa. Arch Biochem Biophys. 2024 Apr;754:109950. doi: 10.1016/j.abb.2024.109950. Epub 2024 Feb 29. Arch Biochem Biophys. 2024. PMID: 38430969 Free article.

3

Selective carbon-hydrogen bond hydroxylation using an engineered cytochrome P450 peroxygenase.

Akter J, Stockdale TP, Child SA, Lee JHZ, De Voss JJ, Bell SG. Akter J, et al. Among authors: child sa. J Inorg Biochem. 2023 Jul;244:112209. doi: 10.1016/j.jinorgbio.2023.112209. Epub 2023 Apr 6. J Inorg Biochem. 2023. PMID: 37080140

4

A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis.

Mohamed H, Child SA, Bruning JB, Bell SG. Mohamed H, et al. Among authors: child sa. J Steroid Biochem Mol Biol. 2022 Jul;221:106097. doi: 10.1016/j.jsbmb.2022.106097. Epub 2022 Mar 25. J Steroid Biochem Mol Biol. 2022. PMID: 35346833

5

The Stereoselective Oxidation of para-Substituted Benzenes by a Cytochrome P450 Biocatalyst.

Chao RR, Lau IC, Coleman T, Churchman LR, Child SA, Lee JHZ, Bruning JB, De Voss JJ, Bell SG. Chao RR, et al. Among authors: child sa. Chemistry. 2021 Oct 21;27(59):14765-14777. doi: 10.1002/chem.202102757. Epub 2021 Sep 12. Chemistry. 2021. PMID: 34350662

6

Kinetic Evidence for an Induced Fit Mechanism in the Binding of the Substrate Camphor by Cytochrome P450_cam.

Guengerich FP, Child SA, Barckhausen IR, Goldfarb MH. Guengerich FP, et al. Among authors: child sa. ACS Catal. 2021 Jan 15;11(2):639-649. doi: 10.1021/acscatal.0c04455. Epub 2020 Dec 29. ACS Catal. 2021. PMID: 34327042 Free PMC article.

7

Characterization of human adrenal cytochrome P450 11B2 products of progesterone and androstenedione oxidation.

Glass SM, Reddish MJ, Child SA, Wilkey CJ, Stec DF, Guengerich FP. Glass SM, et al. Among authors: child sa. J Steroid Biochem Mol Biol. 2021 Apr;208:105787. doi: 10.1016/j.jsbmb.2020.105787. Epub 2020 Nov 12. J Steroid Biochem Mol Biol. 2021. PMID: 33189850 Free PMC article.

8

Functional interactions of adrenodoxin with several human mitochondrial cytochrome P450 enzymes.

Child SA, Reddish MJ, Glass SM, Goldfarb MH, Barckhausen IR, Guengerich FP. Child SA, et al. Arch Biochem Biophys. 2020 Nov 15;694:108596. doi: 10.1016/j.abb.2020.108596. Epub 2020 Sep 24. Arch Biochem Biophys. 2020. PMID: 32980349 Free PMC article.

9

A comparison of steroid and lipid binding cytochrome P450s from Mycobacterium marinum and Mycobacterium tuberculosis.

Child SA, Ghith A, Bruning JB, Bell SG. Child SA, et al. J Inorg Biochem. 2020 Aug;209:111116. doi: 10.1016/j.jinorgbio.2020.111116. Epub 2020 May 20. J Inorg Biochem. 2020. PMID: 32473484

10

Multistep Binding of the Non-Steroidal Inhibitors Orteronel and Seviteronel to Human Cytochrome P450 17A1 and Relevance to Inhibition of Enzyme Activity.

Child SA, Guengerich FP. Child SA, et al. J Med Chem. 2020 Jun 25;63(12):6513-6522. doi: 10.1021/acs.jmedchem.9b01849. Epub 2020 Apr 9. J Med Chem. 2020. PMID: 32223238 Free PMC article.

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