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Large-scale combination screens reveal small-molecule sensitization of antibiotic-resistant gram-negative ESKAPE pathogens.
Tse MW, Zhu M, Peters B, Hamami E, Chen J, Davis KP, Nitz S, Weller J, Warrier T, Hunt DK, Morales Y, Kawate T, Gaulin JL, Come JH, Hernandez-Bird J, Huo W, Neisewander I, Yu X, Aceves-Salvador JA, Kiessling LL, Hung DT, Mecsas J, Aldridge BB, Isberg RR, Blainey PC. Tse MW, et al. Among authors: mecsas j. Proc Natl Acad Sci U S A. 2025 Apr;122(13):e2402017122. doi: 10.1073/pnas.2402017122. Epub 2025 Mar 24. Proc Natl Acad Sci U S A. 2025. PMID: 40127266 Free PMC article.
Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens.
Tse MW, Zhu M, Peters B, Hamami E, Chen J, Davis KP, Nitz S, Weller J, Warrier T, Hunt DK, Morales Y, Kawate T, Gaulin JL, Come JH, Hernandez-Bird J, Huo W, Neisewander I, Kiessling LL, Hung DT, Mecsas J, Aldridge BB, Isberg RR, Blainey PC. Tse MW, et al. Among authors: mecsas j. bioRxiv [Preprint]. 2024 Mar 26:2024.03.26.586803. doi: 10.1101/2024.03.26.586803. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2025 Apr;122(13):e2402017122. doi: 10.1073/pnas.2402017122. PMID: 38585790 Free PMC article. Updated. Preprint.
Robust bioengineered 3D functional human intestinal epithelium.
Chen Y, Lin Y, Davis KM, Wang Q, Rnjak-Kovacina J, Li C, Isberg RR, Kumamoto CA, Mecsas J, Kaplan DL. Chen Y, et al. Among authors: mecsas j. Sci Rep. 2015 Sep 16;5:13708. doi: 10.1038/srep13708. Sci Rep. 2015. PMID: 26374193 Free PMC article.
78 results