Gygi SP - Search Results

1

Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease.

Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: gygi sp. Nat Cell Biol. 2025 Apr;27(4):619-632. doi: 10.1038/s41556-025-01623-y. Epub 2025 Mar 26. Nat Cell Biol. 2025. PMID: 40140603 Free PMC article.

2

A proteomics approach to understanding protein ubiquitination.

Peng J, Schwartz D, Elias JE, Thoreen CC, Cheng D, Marsischky G, Roelofs J, Finley D, Gygi SP. Peng J, et al. Among authors: gygi sp. Nat Biotechnol. 2003 Aug;21(8):921-6. doi: 10.1038/nbt849. Epub 2003 Jul 20. Nat Biotechnol. 2003. PMID: 12872131

3

The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle.

Schmidt M, Haas W, Crosas B, Santamaria PG, Gygi SP, Walz T, Finley D. Schmidt M, et al. Among authors: gygi sp. Nat Struct Mol Biol. 2005 Apr;12(4):294-303. doi: 10.1038/nsmb914. Epub 2005 Mar 20. Nat Struct Mol Biol. 2005. PMID: 15778719

4

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.

Kirkpatrick DS, Hathaway NA, Hanna J, Elsasser S, Rush J, Finley D, King RW, Gygi SP. Kirkpatrick DS, et al. Among authors: gygi sp. Nat Cell Biol. 2006 Jul;8(7):700-10. doi: 10.1038/ncb1436. Epub 2006 Jun 25. Nat Cell Biol. 2006. PMID: 16799550

5

Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

Hanna J, Hathaway NA, Tone Y, Crosas B, Elsasser S, Kirkpatrick DS, Leggett DS, Gygi SP, King RW, Finley D. Hanna J, et al. Among authors: gygi sp. Cell. 2006 Oct 6;127(1):99-111. doi: 10.1016/j.cell.2006.07.038. Cell. 2006. PMID: 17018280 Free article.

6

Ubiquitin chains are remodeled at the proteasome by opposing ubiquitin ligase and deubiquitinating activities.

Crosas B, Hanna J, Kirkpatrick DS, Zhang DP, Tone Y, Hathaway NA, Buecker C, Leggett DS, Schmidt M, King RW, Gygi SP, Finley D. Crosas B, et al. Among authors: gygi sp. Cell. 2006 Dec 29;127(7):1401-13. doi: 10.1016/j.cell.2006.09.051. Cell. 2006. PMID: 17190603 Free article.

7

Phosphoproteome analysis of fission yeast.

Wilson-Grady JT, Villén J, Gygi SP. Wilson-Grady JT, et al. Among authors: gygi sp. J Proteome Res. 2008 Mar;7(3):1088-97. doi: 10.1021/pr7006335. Epub 2008 Feb 8. J Proteome Res. 2008. PMID: 18257517

8

Chaperone-mediated pathway of proteasome regulatory particle assembly.

Roelofs J, Park S, Haas W, Tian G, McAllister FE, Huo Y, Lee BH, Zhang F, Shi Y, Gygi SP, Finley D. Roelofs J, et al. Among authors: gygi sp. Nature. 2009 Jun 11;459(7248):861-5. doi: 10.1038/nature08063. Nature. 2009. PMID: 19412159 Free PMC article.

9

Hexameric assembly of the proteasomal ATPases is templated through their C termini.

Park S, Roelofs J, Kim W, Robert J, Schmidt M, Gygi SP, Finley D. Park S, et al. Among authors: gygi sp. Nature. 2009 Jun 11;459(7248):866-70. doi: 10.1038/nature08065. Nature. 2009. PMID: 19412160 Free PMC article.

10

Enhancement of proteasome activity by a small-molecule inhibitor of USP14.

Lee BH, Lee MJ, Park S, Oh DC, Elsasser S, Chen PC, Gartner C, Dimova N, Hanna J, Gygi SP, Wilson SM, King RW, Finley D. Lee BH, et al. Among authors: gygi sp. Nature. 2010 Sep 9;467(7312):179-84. doi: 10.1038/nature09299. Nature. 2010. PMID: 20829789 Free PMC article.

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