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Page 1
Tecovirimat for Clade I MPXV Infection in the Democratic Republic of Congo.
PALM007 Writing Group; Ali R, Alonga J, Biampata JL, Kombozi Basika M, Maljkovic Berry I, Bisento N, Blum E, Bonnett T, Cone K, Crozier I, Davey R, Dilu A, Dodd LE, Gulati I, Hruby D, Ibanda A, Isse F, Kasareka SS, Kayembe G, Kojan R, Luzolo EK, Lane HC, Lawanga L, Liesenborghs L, Shosongo Lunghe C, Lula Y, Lusakibanza M, Lutete GT, Mbala-Kingebeni P, Miranda A, Mukadi-Bamuleka D, Mukendi G, Lupola PM, Muyembe-Tamfum JJ, Ndungunu R, Nganga B, Ntamabyaliro N, Nussenblatt V, Omulepu I, Omalokoho Onosomba J, Proschan M, Rubenstein K, Saknite I, Schechner A, Shaw-Saliba K, Sivahera B, Smolskis M, Tillman A, Tkaczyk E, Tshimanga C, Tshiani Mbaya O, Tshomba A, Yemba Unda Tshomba F, Vallee D, Vogel S, Weyers S. PALM007 Writing Group, et al. Among authors: hruby d. N Engl J Med. 2025 Apr 17;392(15):1484-1496. doi: 10.1056/NEJMoa2412439. N Engl J Med. 2025. PMID: 40239067 Free PMC article. Clinical Trial.
Overview of the regulatory approval of tecovirimat intravenous formulation for treatment of smallpox: potential impact on smallpox outbreak response capabilities, and future tecovirimat development potential.
Russo AT, Grosenbach DW, Honeychurch KM, Long PG, Hruby DE. Russo AT, et al. Among authors: hruby de. Expert Rev Anti Infect Ther. 2023 Mar;21(3):235-242. doi: 10.1080/14787210.2023.2170350. Epub 2023 Feb 2. Expert Rev Anti Infect Ther. 2023. PMID: 36728515 Free PMC article.
Emerging pharmacological strategies for treating and preventing mpox.
Grosenbach DW, Russo AT, Blum ED, Hruby DE. Grosenbach DW, et al. Among authors: hruby de. Expert Rev Clin Pharmacol. 2023 Jul-Dec;16(9):843-854. doi: 10.1080/17512433.2023.2249820. Epub 2023 Aug 22. Expert Rev Clin Pharmacol. 2023. PMID: 37592723 Review.
Tecovirimat is effective against human monkeypox virus in vitro at nanomolar concentrations.
Frenois-Veyrat G, Gallardo F, Gorgé O, Marcheteau E, Ferraris O, Baidaliuk A, Favier AL, Enfroy C, Holy X, Lourenco J, Khoury R, Nolent F, Grosenbach DW, Hruby DE, Ferrier A, Iseni F, Simon-Loriere E, Tournier JN. Frenois-Veyrat G, et al. Among authors: hruby de. Nat Microbiol. 2022 Dec;7(12):1951-1955. doi: 10.1038/s41564-022-01269-8. Epub 2022 Nov 7. Nat Microbiol. 2022. PMID: 36344621 Free PMC article.
Clinical features and management of human monkeypox: a retrospective observational study in the UK.
Adler H, Gould S, Hine P, Snell LB, Wong W, Houlihan CF, Osborne JC, Rampling T, Beadsworth MB, Duncan CJ, Dunning J, Fletcher TE, Hunter ER, Jacobs M, Khoo SH, Newsholme W, Porter D, Porter RJ, Ratcliffe L, Schmid ML, Semple MG, Tunbridge AJ, Wingfield T, Price NM; NHS England High Consequence Infectious Diseases (Airborne) Network. Adler H, et al. Lancet Infect Dis. 2022 Aug;22(8):1153-1162. doi: 10.1016/S1473-3099(22)00228-6. Epub 2022 May 24. Lancet Infect Dis. 2022. PMID: 35623380 Free PMC article.
230 results