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Automated integration of multi-slice spatial transcriptomics data in 2D and 3D using VR-Omics.
Bienroth D, Charitakis N, Wong D, Zhang YC, Jaeger-Honz S, Ding J, Watt KI, Stolper J, Chambers-Smith H, MacGregor D, Christiansen B, Vivien C, Piers AT, Waylen LN, Hoffmann LB, Tang J, La HM, Du MRM, Mohenska M, Polo JM, Grimmond S, Scott E, Rossello FJ, Porrello ER, Klein K, Nim HT, Elliott DA, Schreiber F, Ramialison M. Bienroth D, et al. Among authors: nim ht. Genome Biol. 2025 Jul 2;26(1):182. doi: 10.1186/s13059-025-03630-6. Genome Biol. 2025. PMID: 40598307 Free PMC article.
Nkx2.7 is a conserved regulator of craniofacial development.
Ford C, de Sena-Tomás C, Wun TTR, Aleman AG, Rangaswamy U, Leyhr J, Nuñez MI, Gao CZ, Nim HT, See M, Coppola U, Waxman JS, Ramialison M, Haitina T, Smeeton J, Sanges R, Targoff KL. Ford C, et al. Among authors: nim ht. Nat Commun. 2025 Apr 23;16(1):3802. doi: 10.1038/s41467-025-58821-3. Nat Commun. 2025. PMID: 40268889 Free PMC article.
Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites.
Bezawork-Geleta A, Devereux CJ, Keenan SN, Lou J, Cho E, Nie S, De Souza DP, Narayana VK, Siddall NA, Rodrigues CHM, Portelli S, Zheng T, Nim HT, Ramialison M, Hime GR, Dodd GT, Hinde E, Ascher DB, Stroud DA, Watt MJ. Bezawork-Geleta A, et al. Among authors: nim ht. Nat Commun. 2025 Mar 3;16(1):2135. doi: 10.1038/s41467-025-57405-5. Nat Commun. 2025. PMID: 40032835 Free PMC article.
Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells.
Ng ES, Sarila G, Li JY, Edirisinghe HS, Saxena R, Sun S, Bruveris FF, Labonne T, Sleebs N, Maytum A, Yow RY, Inguanti C, Motazedian A, Calvanese V, Capellera-Garcia S, Ma F, Nim HT, Ramialison M, Bonifer C, Mikkola HKA, Stanley EG, Elefanty AG. Ng ES, et al. Among authors: nim ht. Nat Biotechnol. 2025 Aug;43(8):1274-1287. doi: 10.1038/s41587-024-02360-7. Epub 2024 Sep 2. Nat Biotechnol. 2025. PMID: 39223325 Free PMC article.
Unraveling the evolutionary origin of the complex Nuclear Receptor Element (cNRE), a cis-regulatory module required for preferential expression in the atrial chamber.
Nunes Santos L, Sousa Costa ÂM, Nikolov M, Carvalho JE, Coelho Sampaio A, Stockdale FE, Wang GF, Andrade Castillo H, Bortoletto Grizante M, Dudczig S, Vasconcelos M, Rosenthal N, Jusuf PR, Nim HT, de Oliveira P, Guimarães de Freitas Matos T, Nikovits W Jr, Tambones IL, Figueira ACM, Schubert M, Ramialison M, Xavier-Neto J. Nunes Santos L, et al. Among authors: nim ht. Commun Biol. 2024 Apr 4;7(1):371. doi: 10.1038/s42003-024-05972-6. Commun Biol. 2024. PMID: 38575811 Free PMC article.
Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment.
Rudraraju R, Gartner MJ, Neil JA, Stout ES, Chen J, Needham EJ, See M, Mackenzie-Kludas C, Yang Lee LY, Wang M, Pointer H, Karavendzas K, Abu-Bonsrah D, Drew D, Yang Sun YB, Tan JP, Sun G, Salavaty A, Charitakis N, Nim HT, Currie PD, Tham WH, Porrello E, Polo JM, Humphrey SJ, Ramialison M, Elliott DA, Subbarao K. Rudraraju R, et al. Among authors: nim ht. Stem Cell Reports. 2023 Jun 13;18(6):1308-1324. doi: 10.1016/j.stemcr.2023.05.007. Stem Cell Reports. 2023. PMID: 37315523 Free PMC article.
Parallel use of pluripotent human stem cell lung and heart models provide new insights for treatment of SARS-CoV-2.
Rudraraju R, Gartner MJ, Neil JA, Stout ES, Chen J, Needham EJ, See M, Mackenzie-Kludas C, Yang Lee LY, Wang M, Pointer H, Karavendzas K, Abu-Bonsrah D, Drew D, Sun YBY, Tan JP, Sun G, Salavaty A, Charitakis N, Nim HT, Currie PD, Tham WH, Porrello E, Polo J, Humphrey SJ, Ramialison M, Elliott DA, Subbarao K. Rudraraju R, et al. Among authors: nim ht. bioRxiv [Preprint]. 2022 Sep 21:2022.09.20.508614. doi: 10.1101/2022.09.20.508614. bioRxiv. 2022. Update in: Stem Cell Reports. 2023 Jun 13;18(6):1308-1324. doi: 10.1016/j.stemcr.2023.05.007. PMID: 36172136 Free PMC article. Updated. Preprint.
37 results