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Sequential decreases in basolateral amygdala response to threat predict failure to recover from PTSD.
Roeckner AR, Lin ER, Hinrichs R, Harnett NG, Lebois LAM, van Rooij SJH, Ely TD, Jovanovic T, Murty VP, Bruce SE, House SL, Beaudoin FL, An X, Neylan TC, Clifford GD, Linnstaedt SD, Germine LT, Rauch SL, Haran JP, Storrow AB, Lewandowski C, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Swor RA, Hudak LA, Pascual JL, Seamon MJ, Datner EM, Pearson C, Peak DA, Merchant RC, Domeier RM, Rathlev NK, O'Neil BJ, Sergot P, Sanchez LD, Joormann J, Sheridan JF, Harte SE, Koenen KC, Kessler RC, McLean SA, Ressler KJ, Stevens JS. Roeckner AR, et al. Among authors: stevens js. Neuropsychopharmacology. 2025 Sep;50(10):1573-1582. doi: 10.1038/s41386-025-02115-1. Epub 2025 May 3. Neuropsychopharmacology. 2025. PMID: 40319171 Free article.
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
Andero R, Brothers SP, Jovanovic T, Chen YT, Salah-Uddin H, Cameron M, Bannister TD, Almli L, Stevens JS, Bradley B, Binder EB, Wahlestedt C, Ressler KJ. Andero R, et al. Among authors: stevens js. Sci Transl Med. 2013 Jun 5;5(188):188ra73. doi: 10.1126/scitranslmed.3005656. Sci Transl Med. 2013. PMID: 23740899 Free PMC article.
A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces.
Almli LM, Stevens JS, Smith AK, Kilaru V, Meng Q, Flory J, Abu-Amara D, Hammamieh R, Yang R, Mercer KB, Binder EB, Bradley B, Hamilton S, Jett M, Yehuda R, Marmar CR, Ressler KJ. Almli LM, et al. Among authors: stevens js. Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):327-36. doi: 10.1002/ajmg.b.32315. Epub 2015 May 18. Am J Med Genet B Neuropsychiatr Genet. 2015. PMID: 25988933 Free PMC article.
DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.
Wingo AP, Almli LM, Stevens JS, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, Bradley B, Binder EB, Jin P, Gibson G, Ressler KJ. Wingo AP, et al. Among authors: stevens js. Nat Commun. 2015 Dec 3;6:10106. doi: 10.1038/ncomms10106. Nat Commun. 2015. PMID: 26632874 Free PMC article.
271 results