Spring DR - Search Results

1

A platform for SpyCatcher conjugation to native antibodies.

Krajcovicova S, Wharton T, Driscoll CL, King TA, Howarth MR, Spring DR. Krajcovicova S, et al. Among authors: spring dr. Chem Sci. 2025 May 6;16(23):10602-10609. doi: 10.1039/d5sc02286j. eCollection 2025 Jun 11. Chem Sci. 2025. PMID: 40386161 Free PMC article.

2

Specific inhibition of CK2α from an anchor outside the active site.

Brear P, De Fusco C, Hadje Georgiou K, Francis-Newton NJ, Stubbs CJ, Sore HF, Venkitaraman AR, Abell C, Spring DR, Hyvönen M. Brear P, et al. Among authors: spring dr. Chem Sci. 2016 Nov 1;7(11):6839-6845. doi: 10.1039/c6sc02335e. Epub 2016 Jul 12. Chem Sci. 2016. PMID: 28451126 Free PMC article.

3

Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst.

Kwan TT, Boutureira O, Frye EC, Walsh SJ, Gupta MK, Wallace S, Wu Y, Zhang F, Sore HF, Galloway WRJD, Chin JW, Welch M, Bernardes GJL, Spring DR. Kwan TT, et al. Among authors: spring dr. Chem Sci. 2017 May 1;8(5):3871-3878. doi: 10.1039/c6sc05313k. Epub 2017 Mar 14. Chem Sci. 2017. PMID: 28966779 Free PMC article.

4

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR. Walsh SJ, et al. Among authors: spring dr. Chem Sci. 2018 Nov 9;10(3):694-700. doi: 10.1039/c8sc04645j. eCollection 2019 Jan 21. Chem Sci. 2018. PMID: 30774870 Free PMC article.

5

Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR. Walsh SJ, et al. Among authors: spring dr. Chem Sci. 2018 Dec 13;10(2):633-634. doi: 10.1039/c8sc90248h. eCollection 2019 Jan 14. Chem Sci. 2018. PMID: 30778404 Free PMC article.

6

Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein-protein interaction.

Iegre J, Brear P, Baker DJ, Tan YS, Atkinson EL, Sore HF, O' Donovan DH, Verma CS, Hyvönen M, Spring DR. Iegre J, et al. Among authors: spring dr. Chem Sci. 2019 Apr 12;10(19):5056-5063. doi: 10.1039/c9sc00798a. eCollection 2019 May 21. Chem Sci. 2019. PMID: 31183056 Free PMC article.

7

Strategies for the Diversity-Oriented Synthesis of Macrocycles.

Mortensen KT, Osberger TJ, King TA, Sore HF, Spring DR. Mortensen KT, et al. Among authors: spring dr. Chem Rev. 2019 Sep 11;119(17):10288-10317. doi: 10.1021/acs.chemrev.9b00084. Epub 2019 Jun 20. Chem Rev. 2019. PMID: 31244001 Review.

8

Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment-Based Drug Discovery.

King TA, Stewart HL, Mortensen KT, North AJP, Sore HF, Spring DR. King TA, et al. Among authors: spring dr. European J Org Chem. 2019 Sep 1;2019(31-32):5219-5229. doi: 10.1002/ejoc.201900847. Epub 2019 Jul 29. European J Org Chem. 2019. PMID: 31598091 Free PMC article.

9

An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds.

Stewart HL, Hanby AR, King TA, Bond AD, Moss TA, Sore HF, Spring DR. Stewart HL, et al. Among authors: spring dr. Chem Commun (Camb). 2020 Jun 23;56(50):6818-6821. doi: 10.1039/d0cc02728f. Chem Commun (Camb). 2020. PMID: 32432281

10

C(sp³)-H arylation to construct all-syn cyclobutane-based heterobicyclic systems: a novel fragment collection.

Osberger TJ, Kidd SL, King TA, Spring DR. Osberger TJ, et al. Among authors: spring dr. Chem Commun (Camb). 2020 Jul 7;56(54):7423-7426. doi: 10.1039/d0cc03237a. Chem Commun (Camb). 2020. PMID: 32490454

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