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Population pharmacokinetics of penicillin G: insights into increased clearance at low concentrations to guide development of improved long-acting formulations for syphilis and prevention of rheumatic fever.
Yoo O, Salman S, Hla TK, Osowicki J, Page-Sharp M, Marsh JA, Barr R, Azzopardi K, Morici M, Batty KT, Enkel SL, Kado J, Hatchuel L, Fulurija A, McCarthy JS, Snelling T, Steer AC, Carapetis J, Manning L. Yoo O, et al. Among authors: mccarthy js. Antimicrob Agents Chemother. 2025 Jul 2;69(7):e0026925. doi: 10.1128/aac.00269-25. Epub 2025 May 20. Antimicrob Agents Chemother. 2025. PMID: 40391929 Free PMC article. Clinical Trial.
Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study.
Osowicki J, Azzopardi KI, Baker C, Waddington CS, Pandey M, Schuster T, Grobler A, Cheng AC, Pollard AJ, McCarthy JS, Good MF, Walker MJ, Dale JB, Batzloff MR, Carapetis JR, Smeesters PR, Steer AC. Osowicki J, et al. Among authors: mccarthy js. Vaccine. 2019 Jun 6;37(26):3485-3494. doi: 10.1016/j.vaccine.2019.03.059. Epub 2019 May 14. Vaccine. 2019. PMID: 31101422
A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study.
Osowicki J, Azzopardi KI, Fabri L, Frost HR, Rivera-Hernandez T, Neeland MR, Whitcombe AL, Grobler A, Gutman SJ, Baker C, Wong JMF, Lickliter JD, Waddington CS, Pandey M, Schuster T, Cheng AC, Pollard AJ, McCarthy JS, Good MF, Dale JB, Batzloff M, Moreland NJ, Walker MJ, Carapetis JR, Smeesters PR, Steer AC. Osowicki J, et al. Among authors: mccarthy js. Lancet Microbe. 2021 Jul;2(7):e291-e299. doi: 10.1016/S2666-5247(20)30240-8. Epub 2021 Apr 15. Lancet Microbe. 2021. PMID: 35544165 Free article.
Ivermectin worthy of further investigation.
Steer AC, Kearns T, Andrews RM, McCarthy JS, Carapetis JR, Currie BJ. Steer AC, et al. Among authors: mccarthy js. Bull World Health Organ. 2009 Oct;87(10):A; author reply B. doi: 10.2471/blt.09.070540. Bull World Health Organ. 2009. PMID: 19876530 Free PMC article. No abstract available.
320 results