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Page 1
Distinct Sarcoma Microenvironments Predict Benefit from Addition of Pembrolizumab to Preoperative Radiotherapy and Surgery in SU2C-SARC032.
Testa S, Himes JE, Subramanian A, Nouth SCL, Ballman KV, Heise RS, Pierpoint M, Nemat-Gorgani N, Sears TJ, Binkley MS, Kalbasi A, Corcoran DL, Hong AM, Brigman BE, Riedel RF, van de Rijn M, Mowery YM, Weinhold KJ, Kirsch DG, Moding EJ. Testa S, et al. Among authors: moding ej. medRxiv [Preprint]. 2025 Nov 4:2025.11.01.25339299. doi: 10.1101/2025.11.01.25339299. medRxiv. 2025. PMID: 41282894 Free PMC article. Preprint.
IL-9 as a naturally orthogonal cytokine with optimal JAK/STAT signaling for engineered T cell therapy.
Jiang H, Limsuwannarot S, Kulhanek KR, Pal A, Labiad O, Rysavy LW, Wong A, Su L, Cavender S, Soro J, Testa S, Ogana H, Waghray D, Tao P, Jude KM, Seet CS, Crooks GM, Moding EJ, Garcia KC, Kalbasi A. Jiang H, et al. Among authors: moding ej. Immunity. 2025 Nov 21:S1074-7613(25)00478-9. doi: 10.1016/j.immuni.2025.10.024. Online ahead of print. Immunity. 2025. PMID: 41274289 Free PMC article.
High throughput mutational characterization of the GPCR ligand C5a using yeast display and deep sequencing.
Xu Y, Thakkar K, Guan L, Miao Y, Mehibel M, Lee RB, Marciano D, Viswanathan V, Wang Z, Wang J, Ji L, Cao H, Petrakian CF, Valenzuela J, LaGory E, Jia X, Moon EJ, Martinez R, Wu F, Frock RL, Moding EJ, Le QT, Rankin EB, Zhang C, Huang P, Olcina MM, Giaccia AJ, Graves EE. Xu Y, et al. Among authors: moding ej. Structure. 2025 Oct 27:S0969-2126(25)00389-2. doi: 10.1016/j.str.2025.10.002. Online ahead of print. Structure. 2025. PMID: 41151574
Future Directions and Priorities for Cellular Therapy in Sarcoma: A Report from the Strategic Advances in Sarcoma Science Cell Therapy Breakout.
Oliva-Ramirez J, Milewski D, Banks L, Bailey KM, Moding EJ, Lake J, Chen A, Daley JD, Resch EE, Kaplan RN, Ladle BH, Zhang L, Chou MM, Nguyen R, Dagalakis U, Al Akoum N, Sorensen PH, Fletcher JA, DeMatteo R, Llosa NJ, Pollack SM. Oliva-Ramirez J, et al. Among authors: moding ej. Cancers (Basel). 2025 Sep 19;17(18):3068. doi: 10.3390/cancers17183068. Cancers (Basel). 2025. PMID: 41008910 Free PMC article. Review.
Distinct cell state ecosystems for nodular lymphocyte-predominant Hodgkin lymphoma.
Subramanian A, Su S, Flerlage J, Alig S, Younes S, Marks LJ, Pinnix C, Vega F, Steiner R, Kumar P, Mocikova H, Sykorova A, Prochazka V, Milito C, Allen P, Paulino D, Ramsay A, Flerlage T, Palese M, West R, Zhu C, Noordenbos T, Schroers-Martin J, Zhao S, Park NJ, Kalbasi A, Moding EJ, Newman AM, Advani RH, Hoppe RT, Diehn M, Natkunam Y, Alizadeh AA, Binkley MS. Subramanian A, et al. Among authors: moding ej. Nat Commun. 2025 Sep 26;16(1):8473. doi: 10.1038/s41467-025-63339-9. Nat Commun. 2025. PMID: 41006203 Free PMC article.
Tegavivint triggers TECR-dependent nonapoptotic cancer cell death.
Leak L, Wang Z, Joseph AJ, Johnson B, Chan AA, Decosto CM, Magtanong L, Ko PJ, Lee WC, Ritho J, Manukian S, Millner A, Chitkara S, Salinas JJ, Skouta R, Rees MG, Ronan MM, Roth JA, Myers CL, Moffat J, Boone C, Bensinger SJ, Nathanson DA, Atilla-Gokcumen GE, Moding EJ, Dixon SJ. Leak L, et al. Among authors: moding ej. Nat Chem Biol. 2025 Dec;21(12):1873-1884. doi: 10.1038/s41589-025-01913-4. Epub 2025 May 26. Nat Chem Biol. 2025. PMID: 40419770
Integrating ctDNA Analysis and Radiomics for Dynamic Risk Assessment in Localized Lung Cancer.
Moding EJ, Shahrokh Esfahani M, Jin C, Hui AB, Nabet BY, Liu Y, Chabon JJ, Binkley MS, Kurtz DM, Hamilton EG, Chaudhuri AA, Liu CL, Li Z, Bonilla RF, Jiang AL, Lau BC, Lopez P, He J, Qiao Y, Xu T, Yao L, Gandhi S, Liao Z, Das M, Ramchandran KJ, Padda SK, Neal JW, Wakelee HA, Gensheimer MF, Loo BW Jr, Li R, Lin SH, Alizadeh AA, Diehn M. Moding EJ, et al. Cancer Discov. 2025 Aug 4;15(8):1609-1629. doi: 10.1158/2159-8290.CD-24-1704. Cancer Discov. 2025. PMID: 40299851
62 results