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Page 1
Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment.
Green WD, Gomez A, Plotkin AL, Pratt BM, Merritt EF, Mullins GN, Kren NP, Modliszewski JL, Zhabotynsky V, Woodcock MG, Green JM, Cannon G, Pipkin ME, Dotti G, Thaxton JE, Pylayeva-Gupta Y, Baldwin AS, Morris JP 4th, Stanley N, Milner JJ. Green WD, et al. Among authors: modliszewski jl. Immunity. 2025 Jul 8;58(7):1725-1741.e9. doi: 10.1016/j.immuni.2025.04.030. Epub 2025 May 26. Immunity. 2025. PMID: 40425012
Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4.
Alicea Pauneto CDM, Riesenberg BP, Gandy EJ, Kennedy AS, Clutton GT, Hem JW, Hurst KE, Hunt EG, Green JM, Miller BC, Angus SP, Johnson GL, Esther RJ, Guerriero JL, Gao P, Soto-Pantoja DR, Ferris RL, Modliszewski JL, Coleman MF, Chung HK, Milner JJ, Moschos SJ, Wiseman RL, Thaxton JE. Alicea Pauneto CDM, et al. Among authors: modliszewski jl. Immunity. 2025 Oct 14;58(10):2489-2504.e8. doi: 10.1016/j.immuni.2025.09.003. Epub 2025 Sep 25. Immunity. 2025. PMID: 41005293 Free article.
Multi-Omics Atlas-Assisted Discovery of Transcription Factors for Selective T Cell State Programming.
Chung HK, Liu C, Battu A, Jambor AN, Pratt BM, Xie F, Riesenberg BP, Casillas E, Sun M, Landoni E, Li Y, Ye Q, Joo D, Green J, Syed Z, Brown NJ, Smith M, Ma S, Tan S, Chick B, Tripple V, Wang ZA, Wang J, Mcdonald B, He P, Yang Q, Chen T, Varanasi SK, LaPorte M, Mann TH, Chen D, Hoffmann F, Ho J, Modliszewski J, Williams A, Liu Y, Wang Z, Liu J, Gao Y, Hu Z, Cho UH, Liu L, Wang Y, Hargreaves DC, Dotti G, Savoldo B, Thaxton JE, Milner JJ, Kaech SM, Wang W. Chung HK, et al. bioRxiv [Preprint]. 2025 Aug 15:2023.01.03.522354. doi: 10.1101/2023.01.03.522354. bioRxiv. 2025. PMID: 36711632 Free PMC article. Preprint.
Correction: An FGFR-p53 developmental signaling axis drives salivary cancer progression.
Musicant AM, Billington JMR, Damrauer JS, Modliszewski JL, Landau LJB, Tsai YH, Mehta JH, Powers J, Betancourt R, Sekhri R, Padilla RJ, Hernandez-Prera JC, Hayes DN, Hackman TG, Gokcumen O, Knox SM, Amelio AL. Musicant AM, et al. Among authors: modliszewski jl. Oncogene. 2025 Aug;44(32):2924. doi: 10.1038/s41388-025-03478-x. Oncogene. 2025. PMID: 40542202 No abstract available.
An FGFR-p53 developmental signaling axis drives salivary cancer progression.
Musicant AM, Billington JMR, Damrauer JS, Modliszewski JL, Landau LJB, Tsai YH, Mehta JH, Powers J, Betancourt R, Sekhri R, Padilla RJ, Hernandez-Prera JC, Hayes DN, Hackman TG, Gokcumen O, Knox SM, Amelio AL. Musicant AM, et al. Among authors: modliszewski jl. Oncogene. 2025 Aug;44(32):2876-2892. doi: 10.1038/s41388-025-03444-7. Epub 2025 Jun 2. Oncogene. 2025. PMID: 40456865
Tumor suppressors in Sox2-mediated lung cancers promote distinct cell-intrinsic and immunologic remodeling.
Sengottuvel N, Whately KM, Modliszewski JL, Sellers RS, Green WD, Gong W, Woods AT, Livingston EW, Fagan-Solis KD, Cannon G, Edatt L, Yuan H, Chack AC, Sanchez Y, Zhou K, Dawoud A, Green JM, Godfrey V, Milner JJ, Gupta GP, Pecot CV. Sengottuvel N, et al. Among authors: modliszewski jl. JCI Insight. 2025 May 6;10(12):e171364. doi: 10.1172/jci.insight.171364. eCollection 2025 Jun 23. JCI Insight. 2025. PMID: 40327401 Free PMC article.
Enhancing radiotherapy response via intratumoral injection of a TLR9 agonist in autochthonous murine sarcomas.
Su C, Kent CL, Pierpoint M, Floyd W, Luo L, Williams NT, Ma Y, Peng B, Lazarides AL, Subramanian A, Himes JE, Perez VM, Hernansaiz-Ballesteros RD, Roche KE, Modliszewski JL, Selitsky SR, Shinohara ML, Wisdom AJ, Moding EJ, Mowery YM, Kirsch DG. Su C, et al. Among authors: modliszewski jl. JCI Insight. 2024 Jun 13;9(14):e178767. doi: 10.1172/jci.insight.178767. JCI Insight. 2024. PMID: 39133651 Free PMC article.
Enhancing radiotherapy response via intratumoral injection of the TLR9 agonist CpG to stimulate CD8 T cells in an autochthonous mouse model of sarcoma.
Su C, Kent CL, Pierpoint M, Floyd W, Luo L, Wiliams NT, Ma Y, Peng B, Lazarides AL, Subramanian A, Himes JE, Perez VM, Hernansaiz-Ballesteros RD, Roche KE, Modliszewski JL, Selitsky SR, Mari Shinohara, Wisdom AJ, Moding EJ, Mowery YM, Kirsch DG. Su C, et al. Among authors: modliszewski jl. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.573968. doi: 10.1101/2024.01.03.573968. bioRxiv. 2024. Update in: JCI Insight. 2024 Jun 13;9(14):e178767. doi: 10.1172/jci.insight.178767. PMID: 38260522 Free PMC article. Updated. Preprint.
Temporary Knockdown of p53 During Focal Limb Irradiation Increases the Development of Sarcomas.
Daniel AR, Su C, Williams NT, Li Z, Huang J, Lopez O, Luo L, Ma Y, Campos LDS, Selitsky SR, Modliszewski JL, Liu S, Hernansaiz-Ballesteros R, Mowery YM, Cardona DM, Lee CL, Kirsch DG. Daniel AR, et al. Among authors: modliszewski jl. Cancer Res Commun. 2023 Dec 5;3(12):2455-2467. doi: 10.1158/2767-9764.CRC-23-0104. Cancer Res Commun. 2023. PMID: 37982576 Free PMC article.
34 results