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Fecal metabolite profiling identifies critically ill patients with increased 30-day mortality.
de Porto AP, Dylla NP, Stutz M, Lin H, Khalid M, Mullowney MW, Little J, Rose A, Moran D, McMillin M, Burgo V, Smith R, Woodson C, Metcalfe C, Ramaswamy R, Lehmann C, Odenwald M, Bandealy N, Zhao J, Kim M, Adler E, Sundararajan A, Sidebottom A, Kress JP, Wolfe KS, Pamer EG, Patel BK. de Porto AP, et al. Among authors: sidebottom a. Sci Adv. 2025 Jun 6;11(23):eadt1466. doi: 10.1126/sciadv.adt1466. Epub 2025 Jun 4. Sci Adv. 2025. PMID: 40465720 Free PMC article.
Immunomodulatory fecal metabolites are associated with mortality in COVID-19 patients with respiratory failure.
Stutz MR, Dylla NP, Pearson SD, Lecompte-Osorio P, Nayak R, Khalid M, Adler E, Boissiere J, Lin H, Leiter W, Little J, Rose A, Moran D, Mullowney MW, Wolfe KS, Lehmann C, Odenwald M, De La Cruz M, Giurcanu M, Pohlman AS, Hall JB, Chaubard JL, Sundararajan A, Sidebottom A, Kress JP, Pamer EG, Patel BK. Stutz MR, et al. Among authors: sidebottom a. Nat Commun. 2022 Nov 3;13(1):6615. doi: 10.1038/s41467-022-34260-2. Nat Commun. 2022. PMID: 36329015 Free PMC article.
Microbially-catalyzed conjugation of GABA and tyramine to bile acids.
Mullowney MW, Fiebig A, Schnizlein MK, McMillin M, Rose AR, Koval J, Rubin D, Dalal S, Sogin ML, Chang EB, Sidebottom AM, Crosson S. Mullowney MW, et al. Among authors: sidebottom am. bioRxiv [Preprint]. 2023 Dec 13:2023.09.25.559407. doi: 10.1101/2023.09.25.559407. bioRxiv. 2023. Update in: J Bacteriol. 2024 Jan 25;206(1):e0042623. doi: 10.1128/jb.00426-23. PMID: 37808758 Free PMC article. Updated. Preprint.
Bifidobacteria metabolize lactulose to optimize gut metabolites and prevent systemic infection in patients with liver disease.
Odenwald MA, Lin H, Lehmann C, Dylla NP, Cole CG, Mostad JD, Pappas TE, Ramaswamy R, Moran A, Hutchison AL, Stutz MR, Dela Cruz M, Adler E, Boissiere J, Khalid M, Cantoral J, Haro F, Oliveira RA, Waligurski E, Cotter TG, Light SH, Beavis KG, Sundararajan A, Sidebottom AM, Reddy KG, Paul S, Pillai A, Te HS, Rinella ME, Charlton MR, Pamer EG, Aronsohn AI. Odenwald MA, et al. Among authors: sidebottom am. Nat Microbiol. 2023 Nov;8(11):2033-2049. doi: 10.1038/s41564-023-01493-w. Epub 2023 Oct 16. Nat Microbiol. 2023. PMID: 37845315 Free PMC article.
Fecal metabolite profiling identifies liver transplant recipients at risk for postoperative infection.
Lehmann CJ, Dylla NP, Odenwald M, Nayak R, Khalid M, Boissiere J, Cantoral J, Adler E, Stutz MR, Dela Cruz M, Moran A, Lin H, Ramaswamy R, Sundararajan A, Sidebottom AM, Little J, Pamer EG, Aronsohn A, Fung J, Baker TB, Kacha A. Lehmann CJ, et al. Among authors: sidebottom am. Cell Host Microbe. 2024 Jan 10;32(1):117-130.e4. doi: 10.1016/j.chom.2023.11.016. Epub 2023 Dec 15. Cell Host Microbe. 2024. PMID: 38103544 Free article.
An evolution-based framework for describing human gut bacteria.
Doran BA, Chen RY, Giba H, Behera V, Barat B, Sundararajan A, Lin H, Sidebottom A, Pamer EG, Raman AS. Doran BA, et al. Among authors: sidebottom a. bioRxiv [Preprint]. 2023 Dec 5:2023.12.04.569969. doi: 10.1101/2023.12.04.569969. bioRxiv. 2023. PMID: 38105970 Free PMC article. Preprint.
Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis.
Zhang JY, Xiao J, Xie B, Barba H, Boachie-Mensah M, Shah RN, Nadeem U, Spedale M, Dylla N, Lin H, Sidebottom AM, D'Souza M, Theriault B, Sulakhe D, Chang EB, Skondra D. Zhang JY, et al. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):21. doi: 10.1167/iovs.64.15.21. Invest Ophthalmol Vis Sci. 2023. PMID: 38108689 Free PMC article.
Microbially catalyzed conjugation of GABA and tyramine to bile acids.
Mullowney MW, Fiebig A, Schnizlein MK, McMillin M, Rose AR, Koval J, Rubin D, Dalal S, Sogin ML, Chang EB, Sidebottom AM, Crosson S. Mullowney MW, et al. Among authors: sidebottom am. J Bacteriol. 2024 Jan 25;206(1):e0042623. doi: 10.1128/jb.00426-23. Epub 2024 Jan 4. J Bacteriol. 2024. PMID: 38174933 Free PMC article.
Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration.
Little AS, Younker IT, Schechter MS, Bernardino PN, Méheust R, Stemczynski J, Scorza K, Mullowney MW, Sharan D, Waligurski E, Smith R, Ramaswamy R, Leiter W, Moran D, McMillin M, Odenwald MA, Iavarone AT, Sidebottom AM, Sundararajan A, Pamer EG, Eren AM, Light SH. Little AS, et al. Among authors: sidebottom am. Nat Microbiol. 2024 Jan;9(1):55-69. doi: 10.1038/s41564-023-01560-2. Epub 2024 Jan 4. Nat Microbiol. 2024. PMID: 38177297 Free PMC article.
230 results