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Page 1
Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury.
Guo Z, Valenzuela Ripoll C, Picataggi A, Rawnsley DR, Ozcan M, Chirinos JA, Chendamarai E, Girardi A, Riehl T, Evie H, Diab A, Kovacs A, Hyrc K, Ma X, Asnani A, Shewale SV, Scherrer-Crosbie M, Cowart LA, Parks JS, Zhao L, Gordon D, Ramirez-Valle F, Margulies KB, Cappola TP, Desai AA, Pedersen LN, Bergom C, Stitziel NO, Rettig MP, DiPersio JF, Hajny S, Christoffersen C, Diwan A, Javaheri A. Guo Z, et al. Among authors: javaheri a. JACC Basic Transl Sci. 2023 Jan 4;8(3):340-355. doi: 10.1016/j.jacbts.2022.09.010. eCollection 2023 Mar. JACC Basic Transl Sci. 2023. PMID: 37034289 Free PMC article.
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk.
Zhang X, Kapoor D, Jeong SJ, Fappi A, Stitham J, Shabrish V, Sergin I, Yousif E, Rodriguez-Velez A, Yeh YS, Park A, Yurdagul A Jr, Rom O, Epelman S, Schilling JD, Sardiello M, Diwan A, Cho J, Stitziel NO, Javaheri A, Lodhi IJ, Mittendorfer B, Razani B. Zhang X, et al. Among authors: javaheri a. Nat Metab. 2024 Feb;6(2):359-377. doi: 10.1038/s42255-024-00984-2. Epub 2024 Feb 19. Nat Metab. 2024. PMID: 38409323 Free PMC article.
Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling.
Islam M, Rawnsley DR, Ma X, Navid W, Zhao C, Guan X, Foroughi L, Murphy JT, Navid H, Weinheimer CJ, Kovacs A, Nigro J, Diwan A, Chang RP, Kumari M, Young ME, Razani B, Margulies KB, Abdellatif M, Sedej S, Javaheri A, Covey DF, Mani K, Diwan A. Islam M, et al. Among authors: javaheri a. J Clin Invest. 2025 Feb 11;135(7):e163730. doi: 10.1172/JCI163730. J Clin Invest. 2025. PMID: 39932799 Free PMC article.
Identification of lysosomal lipolysis as an essential noncanonical mediator of adipocyte fasting and cold-induced lipolysis.
Yeh YS, Evans TD, Iwase M, Jeong SJ, Zhang X, Liu Z, Park A, Ghasemian A, Dianati B, Javaheri A, Kratky D, Kawarasaki S, Goto T, Zhang H, Dutta P, Schopfer FJ, Straub AC, Cho J, Lodhi IJ, Razani B. Yeh YS, et al. Among authors: javaheri a. J Clin Invest. 2025 Mar 17;135(6):e185340. doi: 10.1172/JCI185340. J Clin Invest. 2025. PMID: 40091840 Free PMC article.
Peroxisomal metabolism of branched fatty acids regulates energy homeostasis.
Liu X, He A, Lu D, Hu D, Tan M, Abere A, Goodarzi P, Ahmad B, Kleiboeker B, Finck BN, Zayed M, Funai K, Brestoff JR, Javaheri A, Weisensee P, Mittendorfer B, Hsu FF, Van Veldhoven PP, Razani B, Semenkovich CF, Lodhi IJ. Liu X, et al. Among authors: javaheri a. Nature. 2025 Oct;646(8087):1223-1231. doi: 10.1038/s41586-025-09517-7. Epub 2025 Sep 17. Nature. 2025. PMID: 40963015 Free PMC article.
Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity.
Ozcan M, Guo Z, Valenzuela Ripoll C, Diab A, Picataggi A, Rawnsley D, Lotfinaghsh A, Bergom C, Szymanski J, Hwang D, Asnani A, Kosiborod M, Zheng J, Hayashi RJ, Woodard PK, Kovacs A, Margulies KB, Schilling J, Razani B, Diwan A, Javaheri A. Ozcan M, et al. Among authors: javaheri a. Cell Metab. 2023 Jun 6;35(6):928-942.e4. doi: 10.1016/j.cmet.2023.02.006. Epub 2023 Mar 2. Cell Metab. 2023. PMID: 36868222 Free PMC article. Clinical Trial.
Editorial: Lipids, lipoproteins and COVID-19.
Ozcan M, Zhu X, Zhang H, Javaheri A. Ozcan M, et al. Among authors: javaheri a. Front Cardiovasc Med. 2023 Nov 1;10:1293249. doi: 10.3389/fcvm.2023.1293249. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 38028441 Free PMC article. No abstract available.
Sodium-Glucose Cotransporter Inhibition Preserves Apolipoprotein M During Acute Inflammation in Mice and Humans.
Valenzuela Ripoll C, Lotfinaghsh A, Guo Z, Kumari T, Miyata KN, Sargazi A, Ozcan M, Diab A, Ataran A, Hajirezaei H, Rashidi O, Yu W, Cho Y, Kovacs A, Weinheimer C, Nigro J, Cases O, Kozyraki R, Oscarsson J, Esterline R, Levi M, Berger JH, Schilling JD, Apte RS, Sardiello M, Peikert A, Kosiborod M, Adamo L, Lowenstein C, Christoffersen C, Cho J, Javaheri A. Valenzuela Ripoll C, et al. Among authors: javaheri a. JACC Adv. 2025 Jun;4(6 Pt 2):101839. doi: 10.1016/j.jacadv.2025.101839. JACC Adv. 2025. PMID: 40579057 Free PMC article.
157 results