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Page 1
Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury.
Guo Z, Valenzuela Ripoll C, Picataggi A, Rawnsley DR, Ozcan M, Chirinos JA, Chendamarai E, Girardi A, Riehl T, Evie H, Diab A, Kovacs A, Hyrc K, Ma X, Asnani A, Shewale SV, Scherrer-Crosbie M, Cowart LA, Parks JS, Zhao L, Gordon D, Ramirez-Valle F, Margulies KB, Cappola TP, Desai AA, Pedersen LN, Bergom C, Stitziel NO, Rettig MP, DiPersio JF, Hajny S, Christoffersen C, Diwan A, Javaheri A. Guo Z, et al. Among authors: javaheri a. JACC Basic Transl Sci. 2023 Jan 4;8(3):340-355. doi: 10.1016/j.jacbts.2022.09.010. eCollection 2023 Mar. JACC Basic Transl Sci. 2023. PMID: 37034289 Free PMC article.
Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor-Biased Ligand in Adults With COVID-19: Two Randomized Clinical Trials.
Self WH, Shotwell MS, Gibbs KW, de Wit M, Files DC, Harkins M, Hudock KM, Merck LH, Moskowitz A, Apodaca KD, Barksdale A, Safdar B, Javaheri A, Sturek JM, Schrager H, Iovine N, Tiffany B, Douglas IS, Levitt J, Busse LW, Ginde AA, Brown SM, Hager DN, Boyle K, Duggal A, Khan A, Lanspa M, Chen P, Puskarich M, Vonderhaar D, Venkateshaiah L, Gentile N, Rosenberg Y, Troendle J, Bistran-Hall AJ, DeClercq J, Lavieri R, Joly MM, Orr M, Pulley J, Rice TW, Schildcrout JS, Semler MW, Wang L, Bernard GR, Collins SP; ACTIV-4 Host Tissue Investigators. Self WH, et al. Among authors: javaheri a. JAMA. 2023 Apr 11;329(14):1170-1182. doi: 10.1001/jama.2023.3546. JAMA. 2023. PMID: 37039791 Free PMC article.
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk.
Zhang X, Kapoor D, Jeong SJ, Fappi A, Stitham J, Shabrish V, Sergin I, Yousif E, Rodriguez-Velez A, Yeh YS, Park A, Yurdagul A Jr, Rom O, Epelman S, Schilling JD, Sardiello M, Diwan A, Cho J, Stitziel NO, Javaheri A, Lodhi IJ, Mittendorfer B, Razani B. Zhang X, et al. Among authors: javaheri a. Nat Metab. 2024 Feb;6(2):359-377. doi: 10.1038/s42255-024-00984-2. Epub 2024 Feb 19. Nat Metab. 2024. PMID: 38409323 Free PMC article.
Phosphorylation of CRYAB induces a condensatopathy to worsen post-myocardial infarction left ventricular remodeling.
Islam M, Rawnsley DR, Ma X, Navid W, Zhao C, Guan X, Foroughi L, Murphy JT, Navid H, Weinheimer CJ, Kovacs A, Nigro J, Diwan A, Chang RP, Kumari M, Young ME, Razani B, Margulies KB, Abdellatif M, Sedej S, Javaheri A, Covey DF, Mani K, Diwan A. Islam M, et al. Among authors: javaheri a. J Clin Invest. 2025 Feb 11;135(7):e163730. doi: 10.1172/JCI163730. J Clin Invest. 2025. PMID: 39932799 Free PMC article.
Identification of lysosomal lipolysis as an essential noncanonical mediator of adipocyte fasting and cold-induced lipolysis.
Yeh YS, Evans TD, Iwase M, Jeong SJ, Zhang X, Liu Z, Park A, Ghasemian A, Dianati B, Javaheri A, Kratky D, Kawarasaki S, Goto T, Zhang H, Dutta P, Schopfer FJ, Straub AC, Cho J, Lodhi IJ, Razani B. Yeh YS, et al. Among authors: javaheri a. J Clin Invest. 2025 Mar 17;135(6):e185340. doi: 10.1172/JCI185340. J Clin Invest. 2025. PMID: 40091840 Free PMC article.
Peroxisomal metabolism of branched fatty acids regulates energy homeostasis.
Liu X, He A, Lu D, Hu D, Tan M, Abere A, Goodarzi P, Ahmad B, Kleiboeker B, Finck BN, Zayed M, Funai K, Brestoff JR, Javaheri A, Weisensee P, Mittendorfer B, Hsu FF, Van Veldhoven PP, Razani B, Semenkovich CF, Lodhi IJ. Liu X, et al. Among authors: javaheri a. Nature. 2025 Oct;646(8087):1223-1231. doi: 10.1038/s41586-025-09517-7. Epub 2025 Sep 17. Nature. 2025. PMID: 40963015 Free PMC article.
Induction of TFEB promotes Kupffer cell survival and reduces lipid accumulation in MASLD.
Chan MM, Daemen S, Beatty W, Byrnes K, Cho K, Ferguson D, Feldstein N, Park C, Guo Z, Park AC, Fu CF, Florczak KL, He L, Yang BQ, Javaheri A, Patti GJ, Finck BN, Razani B, Schilling JD. Chan MM, et al. Among authors: javaheri a. Hepatol Commun. 2025 Nov 24;9(12):e0853. doi: 10.1097/HC9.0000000000000853. eCollection 2025 Dec 1. Hepatol Commun. 2025. PMID: 41665896 Free PMC article.
Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity.
Ozcan M, Guo Z, Valenzuela Ripoll C, Diab A, Picataggi A, Rawnsley D, Lotfinaghsh A, Bergom C, Szymanski J, Hwang D, Asnani A, Kosiborod M, Zheng J, Hayashi RJ, Woodard PK, Kovacs A, Margulies KB, Schilling J, Razani B, Diwan A, Javaheri A. Ozcan M, et al. Among authors: javaheri a. Cell Metab. 2023 Jun 6;35(6):928-942.e4. doi: 10.1016/j.cmet.2023.02.006. Epub 2023 Mar 2. Cell Metab. 2023. PMID: 36868222 Free PMC article. Clinical Trial.
164 results