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Page 1
Is highly purified cannabidiol a treatment opportunity for drug-resistant epilepsy in subjects with typical Rett syndrome and CDKL5 deficiency disorder?
Vignoli A, Prato G, Alfei E, Bagnasco I, Danieli A, Celario M, Favaro J, Matricardi S, Operto FF, Orsini A, Bernasconi DP, Pietrafusa N, Ricci E, Manfredini L, Balletto G, Bonanni P, Canevini MP, De Giorgis V, Nobili L, Sartori S, Savini MN, Viganò I, Specchio N. Vignoli A, et al. Among authors: operto ff. Epilepsia Open. 2025 Aug;10(4):1111-1119. doi: 10.1002/epi4.70078. Epub 2025 Jun 21. Epilepsia Open. 2025. PMID: 40543048 Free PMC article.
Expanding the therapeutic role of highly purified cannabidiol in monogenic epilepsies: A multicenter real-world study.
Cerulli Irelli E, Mazzeo A, Caraballo RH, Perulli M, Moloney PB, Peña-Ceballos J, Rubino M, Mieszczanek KM, Santangelo A, Licchetta L, De Giorgis V, Reyes Valenzuela G, Casellato S, Cesaroni E, Operto FF, Domínguez-Carral J, Ramírez-Camacho A, Ferretti A, Santangelo G, Aledo-Serrano A, Rüegger A, Mancardi MM, Prato G, Riva A, Bergonzini L, Cordelli DM, Bonanni P, Bisulli F, Di Gennaro G, Matricardi S, Striano P, Delanty N, Marini C, Battaglia D, Di Bonaventura C, Ramantani G, Gardella E; GENE‐CBD Study Group; Orsini A, Coppola A. Cerulli Irelli E, et al. Among authors: operto ff. Epilepsia. 2025 Jul;66(7):2253-2267. doi: 10.1111/epi.18378. Epub 2025 Mar 24. Epilepsia. 2025. PMID: 40126049 Free PMC article.
Gain of function SCN1A disease-causing variants: Expanding the phenotypic spectrum and functional studies guiding the choice of effective antiseizure medication.
Matricardi S, Cestèle S, Trivisano M, Kassabian B, Leroudier N, Vittorini R, Nosadini M, Cesaroni E, Siliquini S, Marinaccio C, Longaretti F, Podestà B, Operto FF, Luisi C, Sartori S, Boniver C, Specchio N, Vigevano F, Marini C, Mantegazza M. Matricardi S, et al. Among authors: operto ff. Epilepsia. 2023 May;64(5):1331-1347. doi: 10.1111/epi.17509. Epub 2023 Jan 26. Epilepsia. 2023. PMID: 36636894 Review.
Long-term effectiveness of add-on perampanel in patients with Lennox-Gastaut syndrome: A multicenter retrospective study.
Matricardi S, Cesaroni E, Bonanni P, Foschi N, D Aniello A, Di Gennaro G, Striano P, Cappanera S, Siliquini S, Freri E, Ragona F, Granata T, Deleo F, Villani F, Russo A, Messana T, Siri L, Bagnasco I, Vignoli A, Operto FF, Orsini A, Bonuccelli A, Papa A, Peruzzi C, Liguori C, Verrotti A, Chiarelli F, Marini C, Lattanzi S. Matricardi S, et al. Among authors: operto ff. Epilepsia. 2023 Jun;64(6):e98-e104. doi: 10.1111/epi.17601. Epub 2023 Apr 10. Epilepsia. 2023. PMID: 37000415 Free article.
Real-world use of adjunctive perampanel for focal-onset seizures in Italy: A mirroring clinical practice study of perampanel in adults and adolescents (AMPA).
D'Aniello A, Giallonardo AT, Tinuper P, Mecarelli O, Aguglia U, Assenza G, Gambardella A, Canevini MP, Scifo R, Meletti S, De Giorgis V, Bonanni E, Michelucci R, Cerminara C, Romeo A, Vigevano F, Operto FF, Tramacere L, Di Gennaro G; Alfonso Iudice on behalf of the AMPA Study group; Ngo LY, Patten A, Gentile AL, Pecori A, Goldman S. D'Aniello A, et al. Among authors: operto ff. Epilepsia Open. 2025 Aug;10(4):1074-1085. doi: 10.1002/epi4.70068. Epub 2025 Jun 4. Epilepsia Open. 2025. PMID: 40468531 Free article.
Adjunctive cenobamate in people with focal onset seizures: Insights from the Italian Expanded Access Program.
Roberti R, Assenza G, Bisulli F, Boero G, Canafoglia L, Chiesa V, Di Bonaventura C, Di Gennaro G, Elia M, Ferlazzo E, Giordano A, La Neve A, Liguori C, Meletti S, Operto FF, Pietrafusa N, Puligheddu M, Pulitano P, Rosati E, Sammarra I, Tartara E, Vatti G, Villani F; CNB EAP Italy Study Group; Russo E, Lattanzi S. Roberti R, et al. Among authors: operto ff. Epilepsia. 2024 Oct;65(10):2909-2922. doi: 10.1111/epi.18091. Epub 2024 Aug 14. Epilepsia. 2024. PMID: 39140704
Effectiveness of perampanel as only concomitant antiseizure medication for highly active epilepsy: insight from a real-world, multicenter retrospective study.
Pascarella A, Pasquale M, Abelardo D, Gasparini S, Marsico O, Cutellè R, Cianci V, Iudice A, Bisulli F, Bonanni P, Caggia E, D'Aniello A, Di Bonaventura C, DiFrancesco JC, Domina E, Dono F, Gambardella A, Marini C, Marrelli A, Matricardi S, Morano A, Paladin F, Renna R, Piccioli M, Striano P, Ascoli M, La Neve A, Le Piane E, Orsini A, Torino C, Beretta S, Aguglia U, Ferlazzo E; PEROC Study Group. Pascarella A, et al. J Neurol. 2025 Jun 7;272(7):449. doi: 10.1007/s00415-025-13184-z. J Neurol. 2025. PMID: 40483297
Epilepsy, electroclinical features, and long-term outcomes in Pitt-Hopkins syndrome due to pathogenic variants in the TCF4 gene.
Matricardi S, Bonanni P, Iapadre G, Elia M, Cesaroni E, Danieli A, Negrin S, Zagaroli L, Operto FF, Carotenuto M, Pisani F, Turco EC, Orsini A, Bonuccelli A, Savasta S, Concolino D, Di Cara G, Striano P, Verrotti A. Matricardi S, et al. Among authors: operto ff. Eur J Neurol. 2022 Jan;29(1):19-25. doi: 10.1111/ene.15104. Epub 2021 Oct 7. Eur J Neurol. 2022. PMID: 34519126
141 results