Sibiriline, a novel dual inhibitor of necroptosis and ferroptosis, prevents RIPK1 kinase activity and (phospho)lipid peroxidation as a potential therapeutic strategy.
Delehouzé C, Mallais M, Comte A, Lucas R, Baratte B, Bélal S, Autret A, Py N, Steinschneider R, Adoux L, Saintpierre B, Letourneur F, Robert T, Cougoule C, Bomfim C, Planès R, Péricat D, Bulinski JC, Dimanche-Boitrel MT, Goekjian P, Meunier E, Rousselot M, Pratt DA, Bach S.
Delehouzé C, et al. Among authors: py n.
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Cell Death Discov. 2025.
PMID: 41315180
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