Marzouk AA - Search Results

1

Synthesis, antiproliferative evaluation and in silico studies of new quinazoline derivatives as VEGFR-2 inhibitors.

Abdelsalam Ouf AM, Marzouk AA, Shaykoon MSA, Celik I, Bakhotmah DA, Mansour AA, Alamoudi MK, Alfayomy AM, El-Zahabi MA. Abdelsalam Ouf AM, et al. Among authors: marzouk aa. Future Med Chem. 2025 Jun;17(12):1407-1422. doi: 10.1080/17568919.2025.2525073. Epub 2025 Jul 4. Future Med Chem. 2025. PMID: 40613215

2

Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies.

Alfayomy AM, Abdel-Aziz SA, Marzouk AA, Shaykoon MSA, Narumi A, Konno H, Abou-Seri SM, Ragab FAF. Alfayomy AM, et al. Among authors: marzouk aa. Bioorg Chem. 2021 Mar;108:104555. doi: 10.1016/j.bioorg.2020.104555. Epub 2020 Dec 15. Bioorg Chem. 2021. PMID: 33376011

3

Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment.

Marzouk AA, Taher ES, Shaykoon MSA, Lan P, Abd-Allah WH, Aboregela AM, El-Behairy MF. Marzouk AA, et al. Bioorg Chem. 2021 Jun;111:104883. doi: 10.1016/j.bioorg.2021.104883. Epub 2021 Mar 31. Bioorg Chem. 2021. PMID: 33865053

4

Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition.

Amin MM, Abuo-Rahma GEA, Shaykoon MSA, Marzouk AA, Abourehab MAS, Saraya RE, Badr M, Sayed AM, Beshr EAM. Amin MM, et al. Among authors: marzouk aa. Bioorg Chem. 2023 May;134:106444. doi: 10.1016/j.bioorg.2023.106444. Epub 2023 Feb 25. Bioorg Chem. 2023. PMID: 36893547

5

Daptomycin: A Novel Macrocyclic Antibiotic as a Chiral Selector in an Organic Polymer Monolithic Capillary for the Enantioselective Analysis of a Set of Pharmaceuticals.

Fouad A, Marzouk AA, Shaykoon MSA, Ibrahim SM, El-Adl SM, Ghanem A. Fouad A, et al. Among authors: marzouk aa. Molecules. 2021 Jun 9;26(12):3527. doi: 10.3390/molecules26123527. Molecules. 2021. PMID: 34207780 Free PMC article.

6

Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Fluorinated Candidates as PI3K Inhibitors: Targeting Fluorophilic Binding Sites.

Tantawy AH, El-Behairy MF, Abd-Allah WH, Jiang H, Wang MQ, Marzouk AA. Tantawy AH, et al. Among authors: marzouk aa. J Med Chem. 2021 Dec 9;64(23):17468-17485. doi: 10.1021/acs.jmedchem.1c01674. Epub 2021 Nov 18. J Med Chem. 2021. PMID: 34791873

7

Design and synthesis of new 1,6-dihydropyrimidin-2-thio derivatives targeting VEGFR-2: Molecular docking and antiproliferative evaluation.

Marzouk AA, Abdel-Aziz SA, Abdelrahman KS, Wanas AS, Gouda AM, Youssif BGM, Abdel-Aziz M. Marzouk AA, et al. Bioorg Chem. 2020 Sep;102:104090. doi: 10.1016/j.bioorg.2020.104090. Epub 2020 Jul 10. Bioorg Chem. 2020. PMID: 32683176

8

Novel guanidine derivatives targeting leukemia as selective Src/Abl dual inhibitors: Design, synthesis and anti-proliferative activity.

Moustafa AH, AboulMagd AM, Ali AM, Khodairy A, Marzouk AA, Nafady A, T M Nemr M. Moustafa AH, et al. Among authors: marzouk aa. Bioorg Chem. 2024 Jun;147:107410. doi: 10.1016/j.bioorg.2024.107410. Epub 2024 Apr 27. Bioorg Chem. 2024. PMID: 38688197

9

Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity.

Nemr MTM, Sonousi A, Marzouk AA. Nemr MTM, et al. Among authors: marzouk aa. Bioorg Chem. 2020 Dec;105:104446. doi: 10.1016/j.bioorg.2020.104446. Epub 2020 Nov 1. Bioorg Chem. 2020. PMID: 33171405

10

Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives.

Shaykoon MS, Marzouk AA, Soltan OM, Wanas AS, Radwan MM, Gouda AM, Youssif BGM, Abdel-Aziz M. Shaykoon MS, et al. Among authors: marzouk aa. Bioorg Chem. 2020 Jul;100:103933. doi: 10.1016/j.bioorg.2020.103933. Epub 2020 May 15. Bioorg Chem. 2020. PMID: 32446119

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