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BLIMP1 negatively regulates IL-2 signaling in T cells.
Roy S, Ren M, Li P, Cui K, Cao Y, Fisk B, Markowitz TE, Redekar N, Sakamoto K, Nagao K, Oh J, Spolski R, Liao W, Dubois SP, Kelsall BL, Zhao K, Phelan JD, Leonard WJ. Roy S, et al. Among authors: ren m. Sci Adv. 2025 Jul 18;11(29):eadx8105. doi: 10.1126/sciadv.adx8105. Epub 2025 Jul 18. Sci Adv. 2025. PMID: 40680114 Free PMC article.
Transcription factor p73 regulates Th1 differentiation.
Ren M, Kazemian M, Zheng M, He J, Li P, Oh J, Liao W, Li J, Rajaseelan J, Kelsall BL, Peltz G, Leonard WJ. Ren M, et al. Nat Commun. 2020 Mar 19;11(1):1475. doi: 10.1038/s41467-020-15172-5. Nat Commun. 2020. PMID: 32193462 Free PMC article.
An engineered IL-2 partial agonist promotes CD8+ T cell stemness.
Mo F, Yu Z, Li P, Oh J, Spolski R, Zhao L, Glassman CR, Yamamoto TN, Chen Y, Golebiowski FM, Hermans D, Majri-Morrison S, Picton LK, Liao W, Ren M, Zhuang X, Mitra S, Lin JX, Gattinoni L, Powell JD, Restifo NP, Garcia KC, Leonard WJ. Mo F, et al. Among authors: ren m. Nature. 2021 Sep;597(7877):544-548. doi: 10.1038/s41586-021-03861-0. Epub 2021 Sep 15. Nature. 2021. PMID: 34526724 Free PMC article.
Distinct use of super-enhancer elements controls cell type-specific CD25 transcription and function.
Spolski R, Li P, Chandra V, Shin B, Goel S, Sakamoto K, Liu C, Oh J, Ren M, Enomoto Y, West EE, Christensen SM, Wan ECK, Ge M, Lin JX, Yan B, Kazemian M, Yu ZX, Nagao K, Vijayanand P, Rothenberg EV, Leonard WJ. Spolski R, et al. Among authors: ren m. Sci Immunol. 2023 Nov 3;8(89):eadi8217. doi: 10.1126/sciimmunol.adi8217. Epub 2023 Nov 3. Sci Immunol. 2023. PMID: 37922339 Free PMC article.
3,487 results