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Combination of the MTA-Cooperative PRMT5 Inhibitor BMS-986504 and KRAS Inhibitors Is an Effective Treatment Strategy for MTAP-Deleted KRAS-Mutant Pancreatic Cancer.
Drizyte-Miller K, Engstrom LD, Klomp JA, Stalnecker CA, Stamey AG, Taylor KE, Roach MK, Robb R, Waters LM, Calinisan A, Degan S, Chang WH, Helu XM, Nguyen D, Baldelli E, Pierobon M, Petricoin EF, Briere DM, Hallin J, Christensen JG, Bryant KL, Cox AD, Olson P, Der CJ. Drizyte-Miller K, et al. Among authors: robb r. Cancer Res. 2025 Sep 15;85(18):3540-3557. doi: 10.1158/0008-5472.CAN-25-1507. Cancer Res. 2025. PMID: 40694535 Free PMC article.
Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve Is a Therapeutic Strategy for Pancreatic Cancer.
DeLiberty JM, Roach MK, Stalnecker CA, Robb R, Schechter EG, Pieper NL, Taylor KE, Pita LM, Yang R, Bang S, Drizyte-Miller K, Ackermann SE, Nicewarner Peña SR, Baldelli E, Min SM, Drewry DH, Petricoin EF 3rd, Morris JP 4th, Der CJ, Cox AD, Bryant KL. DeLiberty JM, et al. Among authors: robb r. Cancer Res. 2025 Apr 15;85(8):1479-1495. doi: 10.1158/0008-5472.CAN-24-1757. Cancer Res. 2025. PMID: 39932818 Free PMC article.
Altered Gemcitabine and Nab-paclitaxel Scheduling Improves Therapeutic Efficacy Compared with Standard Concurrent Treatment in Preclinical Models of Pancreatic Cancer.
Wolfe AR, Robb R, Hegazi A, Abushahin L, Yang L, Shyu DL, Trevino JG, Cruz-Monserrate Z, Jacob JR, Palanichamy K, Chakravarti A, Williams TM. Wolfe AR, et al. Among authors: robb r. Clin Cancer Res. 2021 Jan 15;27(2):554-565. doi: 10.1158/1078-0432.CCR-20-1422. Epub 2020 Oct 21. Clin Cancer Res. 2021. PMID: 33087331 Free PMC article.
Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions.
Wolfe AR, Cui T, Baie S, Corrales-Guerrero S, Webb A, Castro-Aceituno V, Shyu DL, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Halloran M, Packard R, Robb R, Chen W, Denko N, Lisanti M, Thompson TC, Frank P, Williams TM. Wolfe AR, et al. Among authors: robb r. Sci Adv. 2024 Mar;10(9):eadj3551. doi: 10.1126/sciadv.adj3551. Epub 2024 Mar 1. Sci Adv. 2024. PMID: 38427741 Free PMC article.
Phase I Trial of Trametinib with Neoadjuvant Chemoradiation in Patients with Locally Advanced Rectal Cancer.
Wu C, Williams TM, Robb R, Webb A, Wei L, Chen W, Mikhail S, Ciombor KK, Cardin DB, Timmers C, Krishna SG, Arnold M, Harzman A, Abdel-Misih S, Roychowdhury S, Bekaii-Saab T, Wuthrick E. Wu C, et al. Among authors: robb r. Clin Cancer Res. 2020 Jul 1;26(13):3117-3125. doi: 10.1158/1078-0432.CCR-19-4193. Epub 2020 Apr 6. Clin Cancer Res. 2020. PMID: 32253228 Free PMC article. Clinical Trial.
447 results