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161 results

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Page 1
Impact of Human Epidermal Growth Factor Receptor 2 in Patients With Metastatic Colorectal Cancer Treated With Chemotherapy Plus Bevacizumab or Anti-EGFRs: Exploratory Analysis of Eight Randomized Trials.
Germani MM, Borelli B, Hashimoto T, Nakamura Y, Oldani S, Battaglin F, Bergamo F, Salvatore L, Stahler A, Antoniotti C, Shitara K, Venook A, Oki E, Muro K, Ugolini C, Soeda J, Lonardi S, Pietrantonio F, Lenz HJ, Modest DP, Yoshino T, Cremolini C. Germani MM, et al. Among authors: modest dp. J Clin Oncol. 2025 Sep 4:JCO2501003. doi: 10.1200/JCO-25-01003. Online ahead of print. J Clin Oncol. 2025. PMID: 40906970
Heart Failure Therapy in Patients with Advanced Cancer Receiving Specialized Palliative Care (EMPATICC trial).
Anker MS, Mahabadi AA, Totzeck M, Tewes M, Shahzeb Khan M, Mincu RI, Hendgen-Cotta UB, Michel L, Mathew B, Drescher O, Schuler M, Keller U, Rieger K, Ahn J, Bullinger L, Modest DP, Denecke C, Kretzler L, Ramer LV, Krug D, Landmesser U, Lehmann L, Frey N, Bercker S, Laufs U, Böhm M, Mahfoud F, Merkely B, Diek M, Butler J, Veiser A, Heise T, Hellmich M, Placzek M, Friede T, Anker SD, Rassaf T. Anker MS, et al. Among authors: modest dp. Eur Heart J. 2025 Aug 30:ehaf705. doi: 10.1093/eurheartj/ehaf705. Online ahead of print. Eur Heart J. 2025. PMID: 40884070
Primary tumor sidedness and negative hyperselection to modulate anti-EGFR-based maintenance strategies in patients with RAS wild-type metastatic colorectal cancer: individual patient data pooled analysis of two randomized clinical trials.
Ballhausen A, Morano F, Stahler A, Lonardi S, Kind AJ, Cremolini C, Swoboda S, Randon G, Horst D, Prisciandaro M, Alig AHS, Pircher CC, Jarosch A, Andena P, Kurreck A, Chiaramonte AA, Stintzing S, Pietrantonio F, Modest DP, Raimondi A. Ballhausen A, et al. Among authors: modest dp. Br J Cancer. 2025 Aug 28. doi: 10.1038/s41416-025-03164-5. Online ahead of print. Br J Cancer. 2025. PMID: 40877636
Randomized investigation of heart failure therapy in patients with advanced cancer at risk of cardiac wasting: Rationale and design of the EMPATICC trial.
Anker MS, Mahabadi AA, Totzeck M, Tewes M, Mincu R, Khan MS, Butler J, Keller U, Ahn J, Bullinger L, Modest DP, Landmesser U, Lehmann LH, Bercker S, Laufs U, Böhm M, Merkely B, Diek M, Heise T, Hellmich M, Placzek M, Friede T, Anker SD, Rassaf T. Anker MS, et al. Among authors: modest dp. Eur J Heart Fail. 2025 Aug 26. doi: 10.1002/ejhf.3799. Online ahead of print. Eur J Heart Fail. 2025. PMID: 40857084
Risk of disease progression in the first-line therapy of metastatic colorectal cancer to guide disease re-assessments - analysis of eleven trials by AIO and GONO.
Germani MM, Heinemann V, Rossini D, Fischer von Weikersthal L, Pietrantonio F, Heinrich K, Stahler A, Lonardi S, Kaiser F, Decker T, Salvatore L, Weiss L, Morano F, Fuchs M, Bergamo F, Antoniotti C, Masi G, Stintzing S, Frumento P, Cremolini C, Modest DP. Germani MM, et al. Among authors: modest dp. Ann Oncol. 2025 Aug 19:S0923-7534(25)00921-4. doi: 10.1016/j.annonc.2025.08.001. Online ahead of print. Ann Oncol. 2025. PMID: 40840710 Free article.
Health-related quality of life in patients with KRASG12C-mutated chemorefractory metastatic colorectal cancer treated with sotorasib plus panitumumab or standard of care (CodeBreaK 300): results from a phase 3, randomised clinical trial.
Modest DP, Fakih M, Salvatore L, Esaki T, Lopez-Bravo DP, Taieb J, Karamouzis M, Ruiz-Garcia E, Kim TW, Kuboki Y, Meriggi F, Cunningham D, Yeh KH, Cremolini C, Tran Q, Chan E, Chao J, Majer IM, Pietrantonio F. Modest DP, et al. Lancet Oncol. 2025 Sep;26(9):1240-1251. doi: 10.1016/S1470-2045(25)00352-3. Epub 2025 Aug 11. Lancet Oncol. 2025. PMID: 40812325 Free article. Clinical Trial.
Clinical and echocardiographic phenotype of cardiac wasting in patients with advanced cancer.
Anker MS, Khan MS, Nikolski A, Porthun J, Arshad MS, Hadzibegovic S, Lena A, Kretzler L, Hella JL, Witkowski M, Rieger K, Ahn J, Modest DP, Keller U, Bullinger L, Totzeck M, Mahabadi AA, Rassaf T, Buchmann N, Attanasio P, Zeller T, Karakas M, Tocchetti CG, Wilkenshoff U, Cleland JGF, von Haehling S, Butler J, Landmesser U. Anker MS, et al. Among authors: modest dp. Eur J Heart Fail. 2025 Aug 6. doi: 10.1002/ejhf.3744. Online ahead of print. Eur J Heart Fail. 2025. PMID: 40767389
Spatial tumor immune microenvironment as a prognostic and predictive biomarker in anti-EGFR-based maintenance for RAS wt metastatic CRC - the PanaMa (AIO KRK0212) trial.
Ballhausen A, Swoboda S, Horst D, Fruehauf S, Graeven U, Müller L, Trarbach T, Fischer von Weikersthal L, Goekkurt E, Heinemann V, Kasper S, Kurreck A, Alig AHS, Reinacher-Schick AC, Bullinger L, Stahler A, Stintzing S, Jarosch A, Modest DP. Ballhausen A, et al. Among authors: modest dp. Clin Cancer Res. 2025 Jul 30. doi: 10.1158/1078-0432.CCR-25-0879. Online ahead of print. Clin Cancer Res. 2025. PMID: 40736443
FOLFIRINOX or FOLFOX for locally advanced or metastatic small bowel adenocarcinoma: PRODIGE 86 - FFCD-GONO - ENGIC 02 - FOLFIRINOX SBA phase II randomized trial.
Aparicio T, Turpin A, Zaanan A, de la Fouchardière C, Le Malicot K, Lonardi S, Modest DP, Wilson R, Cremolini C, Ballhausen A, Graham J, Kurreck A, Guarssifi M, Svrcek M, Laurent-Puig P, Manfredi S. Aparicio T, et al. Among authors: modest dp. Dig Liver Dis. 2025 Oct;57(10):2001-2005. doi: 10.1016/j.dld.2025.07.018. Epub 2025 Jul 28. Dig Liver Dis. 2025. PMID: 40730749 Free article.
Impact of trifluridine/tipiracil plus bevacizumab on tumor shrinkage and depth of response in refractory metastatic colorectal cancer: analysis of the SUNLIGHT trial.
Taieb J, Modest DP, Fakih M, Ciardiello F, Van Cutsem E, Elez E, Gravalos C, Bragagnoli AC, Barboux V, Roby L, Amellal N, Prager GW. Taieb J, et al. Among authors: modest dp. Eur J Cancer. 2025 Sep 9;227:115644. doi: 10.1016/j.ejca.2025.115644. Epub 2025 Jul 12. Eur J Cancer. 2025. PMID: 40694985 Free article. Clinical Trial.
161 results