Marshak-Rothstein A - Search Results

1

Endothelial Cell Expression of STING ^V154M Gain-of-Function Mutation Delays the Resolution of UVB-induced Skin Injury.

Chuprin J, Lopes CS, Gao KM, Chiang K, Afshari K, Haddadi N, Garber M, Koupenova M, Fitzgerald KA, Marshak-Rothstein A, Rashighi M. Chuprin J, et al. Among authors: marshak rothstein a. bioRxiv [Preprint]. 2025 Jul 18:2025.07.14.664621. doi: 10.1101/2025.07.14.664621. bioRxiv. 2025. PMID: 40791446 Free PMC article. Preprint.

2

Activation of Autoreactive Lymphocytes in the Lung by STING Gain-of-function Mutation Radioresistant Cells.

Gao KM, Nündel K, Chiang K, Yin X, Utz PJ, Fitzgerald K, Marshak-Rothstein A. Gao KM, et al. bioRxiv [Preprint]. 2023 Jul 28:2023.07.28.551002. doi: 10.1101/2023.07.28.551002. bioRxiv. 2023. Update in: JCI Insight. 2024 Jul 18;9(16):e174331. doi: 10.1172/jci.insight.174331. PMID: 37546720 Free PMC article. Updated. Preprint.

3

Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs.

Gao KM, Chiang K, Korkmaz FT, Janardhan HP, Trivedi CM, Quinton LJ, Gingras S, Fitzgerald KA, Marshak-Rothstein A. Gao KM, et al. bioRxiv [Preprint]. 2023 Jul 27:2023.07.27.550897. doi: 10.1101/2023.07.27.550897. bioRxiv. 2023. Update in: Cell Rep. 2024 Apr 23;43(4):114114. doi: 10.1016/j.celrep.2024.114114. PMID: 37547024 Free PMC article. Updated. Preprint.

4

IFNγ initiates TLR9-dependent autoimmune hepatitis in DNase II deficient mice.

Hao K, Gao KM, Strauss M, Subramanian S, Marshak-Rothstein A. Hao K, et al. Among authors: marshak rothstein a. bioRxiv [Preprint]. 2024 Jul 16:2024.07.10.602775. doi: 10.1101/2024.07.10.602775. bioRxiv. 2024. PMID: 39071327 Free PMC article. Preprint.

5

Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice.

Gao KM, Motwani M, Tedder T, Marshak-Rothstein A, Fitzgerald KA. Gao KM, et al. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2202327119. doi: 10.1073/pnas.2202327119. Epub 2022 Jun 13. Proc Natl Acad Sci U S A. 2022. PMID: 35696583 Free PMC article.

6

Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models.

Motwani M, Pawaria S, Bernier J, Moses S, Henry K, Fang T, Burkly L, Marshak-Rothstein A, Fitzgerald KA. Motwani M, et al. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7941-7950. doi: 10.1073/pnas.1818281116. Epub 2019 Apr 3. Proc Natl Acad Sci U S A. 2019. PMID: 30944222 Free PMC article.

7

cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE.

Motwani M, McGowan J, Antonovitch J, Gao KM, Jiang Z, Sharma S, Baltus GA, Nickerson KM, Marshak-Rothstein A, Fitzgerald KA. Motwani M, et al. Front Immunol. 2021 Mar 29;12:605930. doi: 10.3389/fimmu.2021.605930. eCollection 2021. Front Immunol. 2021. PMID: 33854495 Free PMC article.

8

STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice.

Baum R, Sharma S, Organ JM, Jakobs C, Hornung V, Burr DB, Marshak-Rothstein A, Fitzgerald KA, Gravallese EM. Baum R, et al. Arthritis Rheumatol. 2017 Feb;69(2):460-471. doi: 10.1002/art.39863. Arthritis Rheumatol. 2017. PMID: 27740718 Free PMC article.

9

Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.

Baum R, Nündel K, Pawaria S, Sharma S, Busto P, Fitzgerald KA, Gravallese EM, Marshak-Rothstein A. Baum R, et al. J Immunol. 2016 Feb 1;196(3):1348-54. doi: 10.4049/jimmunol.1502130. Epub 2016 Jan 4. J Immunol. 2016. PMID: 26729810 Free PMC article.

10

Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.

Baum R, Sharma S, Carpenter S, Li QZ, Busto P, Fitzgerald KA, Marshak-Rothstein A, Gravallese EM. Baum R, et al. J Immunol. 2015 Feb 1;194(3):873-7. doi: 10.4049/jimmunol.1402573. Epub 2014 Dec 29. J Immunol. 2015. PMID: 25548216 Free PMC article.

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