Perlmutter JS - Search Results

1

Pilot Study of [¹¹C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer.

Hsieh CJ, Saturnino Guarino D, Young AJ, Siderowf AD, Nasrallah I, Schmitz A, Garcia C, Kim HY, Schubert EK, Lee H, Perlmutter JS, Mach RH. Hsieh CJ, et al. Among authors: perlmutter js. Cells. 2025 Jul 26;14(15):1157. doi: 10.3390/cells14151157. Cells. 2025. PMID: 40801590 Free PMC article.

2

Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer.

Qiu L, Jiang H, Cho K, Yu Y, Jones LA, Huang T, Perlmutter JS, Gropler RJ, Brier MR, Patti GJ, Benzinger TLS, Tu Z. Qiu L, et al. Among authors: perlmutter js. ACS Chem Neurosci. 2024 May 1;15(9):1882-1892. doi: 10.1021/acschemneuro.4c00077. Epub 2024 Apr 18. ACS Chem Neurosci. 2024. PMID: 38634759 Free PMC article.

3

Quantitative Analysis of S1PR1 Expression in the Postmortem Multiple Sclerosis Central Nervous System.

Jiang H, Zhou C, Qiu L, Gropler RJ, Brier MR, Wu GF, Cross AH, Perlmutter JS, Benzinger TLS, Tu Z. Jiang H, et al. Among authors: perlmutter js. ACS Chem Neurosci. 2023 Nov 15;14(22):4039-4050. doi: 10.1021/acschemneuro.3c00581. Epub 2023 Oct 26. ACS Chem Neurosci. 2023. PMID: 37882753 Free PMC article.

4

Synthesis and in vitro evaluation of novel compounds and discovery of a promising iodine-125 radioligand for purinergic P2X7 receptor (P2X7R).

Qiu L, Wang J, Tewari M, Rensing DT, Egan TM, Perlmutter JS, Tu Z. Qiu L, et al. Among authors: perlmutter js. Bioorg Med Chem. 2025 Feb 1;118:118054. doi: 10.1016/j.bmc.2024.118054. Epub 2024 Dec 22. Bioorg Med Chem. 2025. PMID: 39740572 Free PMC article.

5

Synthesis and in vivo biological characterization of six carbon-11 sigma-1 receptor radiotracers in rodent and nonhuman primate.

Soda AK, Huang T, Zhou W, Chen H, Jiang H, Jadhav SB, Xing Z, Yu Y, Tian L, Wong DF, Perlmutter JS, Ni R, Benzinger TLS, Tu Z. Soda AK, et al. Among authors: perlmutter js. Bioorg Med Chem. 2025 Aug 15;126:118218. doi: 10.1016/j.bmc.2025.118218. Epub 2025 Apr 28. Bioorg Med Chem. 2025. PMID: 40339216

6

Cell-free RNA signatures predict Alzheimer's disease.

Cisterna-García A, Beric A, Ali M, Pardo JA, Chen HH, Fernandez MV, Norton J, Gentsch J, Bergmann K, Budde J, Perlmutter JS, Morris JC, Cruchaga C, Botia JA, Ibanez L. Cisterna-García A, et al. Among authors: perlmutter js. iScience. 2023 Nov 23;26(12):108534. doi: 10.1016/j.isci.2023.108534. eCollection 2023 Dec 15. iScience. 2023. PMID: 38089583 Free PMC article.

7

Human striatal glia differentially contribute to AD- and PD-specific neurodegeneration.

Xu J, Farsad HL, Hou Y, Barclay K, Lopez BA, Yamada S, Saliu IO, Shi Y, Knight WC, Bateman RJ, Benzinger TLS, Yi JJ, Li Q, Wang T, Perlmutter JS, Morris JC, Zhao G. Xu J, et al. Among authors: perlmutter js. Nat Aging. 2023 Mar;3(3):346-365. doi: 10.1038/s43587-023-00363-8. Epub 2023 Feb 9. Nat Aging. 2023. PMID: 36993867 Free PMC article.

8

Diffusion Tensor Imaging Along the Perivascular Space (DTI-ALPS): Still Mountains to Climb.

Maiti B, Perlmutter JS. Maiti B, et al. Among authors: perlmutter js. Neurology. 2025 Oct 7;105(7):e214130. doi: 10.1212/WNL.0000000000214130. Epub 2025 Sep 16. Neurology. 2025. PMID: 40956988 No abstract available.

9

Cholinergic dysfunction in occupational manganese exposure.

Hutson TN, Nielsen SS, Senini N, O'Donnell J, Flores HP, Hershey T, Perlmutter JS, Soda AK, Moerlein SM, Tu Z, Kasper M, Sheppard L, Racette BA, Criswell SR. Hutson TN, et al. Among authors: perlmutter js. Neurotoxicology. 2025 Sep 3;111:103313. doi: 10.1016/j.neuro.2025.103313. Online ahead of print. Neurotoxicology. 2025. PMID: 40912474 Free article.

10

Automated production of radiotracer [¹⁸F]FZTA for imaging sphingosine-1-phosphate receptor 1 (S1PR1) in human.

Qiu L, Bognar C, Tangadanchu VKR, Moerlein SM, Gaehle GG, Gropler RJ, Perlmutter JS, Benzinger TLS, Tu Z. Qiu L, et al. Among authors: perlmutter js. Appl Radiat Isot. 2025 Aug 25;226:112136. doi: 10.1016/j.apradiso.2025.112136. Online ahead of print. Appl Radiat Isot. 2025. PMID: 40884909

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