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DAXX promotes centromeric stability independently of ATRX by preventing the accumulation of R-loop-induced DNA double-stranded breaks.
Pinto LM, Pailas A, Bondarchenko M, Sharma AB, Neumann K, Rizzo AJ, Jeanty C, Nicot N, Racca C, Graham MK, Naughton C, Liu Y, Chen CL, Meakin PJ, Gilbert N, Britton S, Meeker AK, Heaphy CM, Larminat F, Van Dyck E. Pinto LM, et al. Among authors: chen cl. Nucleic Acids Res. 2024 Feb 9;52(3):1136-1155. doi: 10.1093/nar/gkad1141. Nucleic Acids Res. 2024. PMID: 38038252 Free PMC article.
Cohesin-mediated loop anchors confine the locations of human replication origins.
Emerson DJ, Zhao PA, Cook AL, Barnett RJ, Klein KN, Saulebekova D, Ge C, Zhou L, Simandi Z, Minsk MK, Titus KR, Wang W, Gong W, Zhang D, Yang L, Venev SV, Gibcus JH, Yang H, Sasaki T, Kanemaki MT, Yue F, Dekker J, Chen CL, Gilbert DM, Phillips-Cremins JE. Emerson DJ, et al. Among authors: chen cl. Nature. 2022 Jun;606(7915):812-819. doi: 10.1038/s41586-022-04803-0. Epub 2022 Jun 8. Nature. 2022. PMID: 35676475 Free PMC article.
OKseqHMM: a genome-wide replication fork directionality analysis toolkit.
Liu Y, Wu X, d'Aubenton-Carafa Y, Thermes C, Chen CL. Liu Y, et al. Among authors: chen cl. Nucleic Acids Res. 2023 Feb 28;51(4):e22. doi: 10.1093/nar/gkac1239. Nucleic Acids Res. 2023. PMID: 36629249 Free PMC article.
To study the direction of replication fork movement and TRCs, we developed a bioinformatics toolkit called OKseqHMM (https://github.com/CL-CHEN-Lab/OK-Seq, https://doi.org/10.5281/zenodo.7428883). Then, we used OKseqHMM to analyse a large number of datasets obtained …
To study the direction of replication fork movement and TRCs, we developed a bioinformatics toolkit called OKseqHMM (https://github.com/C …
4,776 results